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Primary care diagnostic pathways for lower gastrointestinal symptoms
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39674229
No Abstract
Pentosan polysulfate sodium maculopathy: Final analysis of a prospective cohort, updated review, and association with inflammatory bowel disease
Publication Year: 2025 Source: Surv Ophthalmol PMID: 39674406 DOI: 10.1016/j.survophthal.2024.12.002
Pentosan polysulfate sodium (PPS) maculopathy is a recently described condition of macular toxicity. We report the prevalence (15 %), the clinical characteristics, and the multimodal imaging (MMI) features of PPS maculopathy based on a final prospective analysis of a cohort of 154 subjects and highlight the association with inflammatory bowel …
Transcriptomics and metabolomics reveal the alleviation effect of pectic polysaccharide on dextran sodium sulfate-induced colitis mice
Publication Year: 2025 Source: Int J Biol Macromol PMID: 39674473
No Abstract
Early-life gut inflammation drives sex-dependent shifts in the microbiome-endocrine-brain axis
Publication Year: 2025 Source: Brain Behav Immun PMID: 39674560 DOI: 10.1016/j.bbi.2024.12.003
Despite recent advances in understanding the connection between the gut microbiota and the adult brain, significant knowledge gaps remain regarding how gut inflammation affects brain development. We hypothesized that gut inflammation during early life would negatively affect neurodevelopment by disrupting microbiota communication to the brain. We therefore developed a novel …
Author's reply: "Are early-life exposures associated with inflammatory bowel disease? A critique of a recent nested case-control study"
Publication Year: 2025 Source: Dig Liver Dis PMID: 39674775
No Abstract
TTC7A missense variants in intestinal disease can be classified by molecular and cellular phenotypes
Publication Year: 2025 Source: Hum Mol Genet PMID: 39675053 DOI: 10.1093/hmg/ddae185
Biallelic mutations in tetratricopeptide repeat domain 7A (TTC7A) give rise to intestinal and immune disorders. However, our understanding of the genotype-phenotype relationship is limited, because TTC7A variants are mostly compound heterozygous and the disease phenotypes are highly diverse. This study aims to clarify how different TTC7A variants impact the severity …
Patterns of bacterial viability governing noncanonical inflammasome activation
Publication Year: 2025 Source: Curr Opin Immunol PMID: 39675154
No Abstract
Polyphenols-rich Portulaca oleracea L. (purslane) alleviates ulcerative colitis through restiring the intestinal barrier, gut microbiota and metabolites
Publication Year: 2025 Source: Food Chem PMID: 39675274
No Abstract
The role of macrophage polarization in ulcerative colitis and its treatment
Publication Year: 2025 Source: Microb Pathog PMID: 39675441
No Abstract
Diagnosis and management of sclerosing cholangitis and inflammatory bowel disease in children: A survey by SIGENP
Publication Year: 2025 Source: Dig Liver Dis PMID: 39676009
No Abstract
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