Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Difference in the Prognostic Benefit Between Extended and Segmental Colectomy for Patients With Neoplasia Associated With Ulcerative Colitis: A Nationwide Multicenter Study
Publication Year: 2025 Source: Dis Colon Rectum PMID: 40152336
BACKGROUND: Extended colectomy is considered a standard treatment for neoplasia associated with ulcerative colitis, but there is limited supporting evidence, particularly from large-scale studies. OBJECTIVE: This study aimed to assess the prognostic benefits of extended colectomy in patients with neoplasia associated with ulcerative colitis using a nationwide database. DESIGN: Multicenter …
Therapeutic Drug Monitoring of Thiopurines in Patients With Inflammatory Bowel Disease: Observations From Daily Practice
Publication Year: 2025 Source: Ther Drug Monit PMID: 40152645 DOI: 10.1097/FTD.0000000000001327
BACKGROUND: Patients with inflammatory bowel disease (IBD) to be treated with thiopurines should undergo preemptive genotyping for reduced-function thiopurine methyltransferase (TPMT) polymorphisms. Therapeutic drug monitoring (TDM) is recommended in cases of toxicity or a lack of efficacy. The relationship between TPMT genotype and 6-thioguanine nucleotide (6-TGN) and 6-methylmercaptopurine (6-MMP) concentrations …
Ηidradenitis suppurativa associated with autoimmunity in children and adolescents; a case-based review
Publication Year: 2025 Source: Rheumatol Int PMID: 40153074
Hidradenitis suppurativa (HS) is an uncommon chronic inflammatory disease in children, characterized by painful abscesses and lesions. It has been associated with various autoimmune conditions, including inflammatory bowel diseases (IBDs) and rheumatologic disorders. We present a 13-year-old female with Hurley stage III HS, who developed macrophage activation syndrome (MAS). Clinical …
Hepatic Encephalopathy: Current Thoughts on Pathophysiology and Management
Publication Year: 2025 Source: Curr Neurol Neurosci Rep PMID: 40153081
PURPOSE OF REVIEW: This review highlights the causes, types and clinical staging of hepatic encephalopathy (HE). Current concepts on the probable pathogenetic mechanisms and currently practiced therapeutic options are discussed. RECENT FINDINGS: HE may be covert and overt. Also known as minimal HE. Covert HE, where there are behavioral abnormalities …
Gene expression profile in ulcerative colitis patients: FOXO4, ALDOB, SLC26A3, SOD2 genes as potential biomarkers
Publication Year: 2025 Source: Genes Genomics PMID: 40153227 DOI: 10.1007/s13258-025-01625-y
BACKGROUND: Ulcerative colitis (UC) is a complex, chronic inflammatory disease that primarily impacts the colon mucosa. One of the key pathological contributors to the development and progression of inflammatory bowel disease (IBD) is oxidative stress, which results in reactive oxygen species (ROS)-induced mucosal damage. This stress leads to dysfunction of …
Questioning the diagnosis of familial Mediterranean fever based solely on MEFV mutation: a critical review of overlapping features with inflammatory bowel disease
Publication Year: 2025 Source: Clin Exp Rheumatol PMID: 40153317
No Abstract
Integrated analysis and single-cell sequencing of mitochondrial metabolism related gene molecular subtype and diagnostic model in ulcerative colitis
Publication Year: 2025 Source: PLoS One PMID: 40153427
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that seriously affects the life expectancy of patients. Although increasingly sophisticated combinations of drugs can alleviate symptoms, 10-20% of patients still do not respond well. Therefore, it is necessary to further explore the pathogenesis and potential biomarkers of UC. Many clues …
Mendelian randomization study of circulating leukocytes counts reveals causal associations with inflammatory bowel disease
Publication Year: 2025 Source: Medicine (Baltimore) PMID: 40153772 DOI: 10.1097/MD.0000000000041969
Inflammatory bowel disease (IBD) is a chronic recurrent IBD, whose cause involves the interaction between genetic and environmental factors. Although there is a recognized link between immune response and IBD, the causal relationship between circulating immune cell counts and IBD remains controversial. This study aimed to elucidate the causal relationship …
The Efficacy of Traditional Chinese Medicine for Crohn's Disease Treatment: A Systematic Review and Meta-Analysis
Publication Year: 2025 Source: J Gastrointestin Liver Dis PMID: 40153809
BACKGROUND AND AIMS: Crohn's disease (CD) is an inflammatory bowel disease with limited treatment options for patients with mild to moderately active disease. There is a lack of consensus for using traditional Chinese medicine (TCM) for symptom relief. This review aimed to assess the efficacy of TCM compared to placebo …
Colitis Trouble up High: A Case of Gastroduodenal Ulcerative Colitis and Literature Review
Publication Year: 2025 Source: J Gastrointestin Liver Dis PMID: 40153811
BACKGROUND AND AIMS: The presence of backwash ileitis, post-colectomy pre-pouch ileitis, or pouchitis has been widely described in the presentation of ulcerative colitis [UC]. However, over the years, a few cases of upper gastrointestinal [UGI] inflammation in patients with UC have been reported, most commonly post-colectomy. The aim of this …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide