Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
A Comprehensive Review of Geriatric Syndromes and Assessment in Older Adults With Inflammatory Bowel Diseases
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40081635 DOI: 10.1016/j.cgh.2024.09.042
OBJECTIVE & AIMS: Older patients with inflammatory bowel disease (IBD) constitute an increasingly prevalent population. There is growing recognition of the prevalence and impact of geriatric syndromes on patients with IBD. We aimed to critically review available data on geriatric syndromes in patients with IBD. METHODS: An electronic systematic bibliographic …
Intestinal Ultrasound Findings and Their Prognostic Value in Early Crohn's Disease: A Copenhagen IBD Cohort Study
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 40081637
BACKGROUND & AIMS: We characterize the sonographic features of Crohn's disease at diagnosis and evaluate the prognostic value of intestinal ultrasound during the early stage of disease. METHODS: A prospective, population-based cohort of patients with newly diagnosed Crohn's disease were followed with intestinal ultrasound in conjunction with symptomatic, biochemical, and …
Metabolic responses to surgical stress
Publication Year: 2025 Source: Clin Nutr ESPEN PMID: 40081803
No Abstract
Racial differences in primary sclerosing cholangitis: A retrospective cohort study leveraging a new ICD-10 code
Publication Year: 2025 Source: Ann Hepatol PMID: 40081809 DOI: 10.1016/j.aohep.2025.101901
INTRODUCTION AND OBJECTIVES: There are limited data examining racial disparities in PSC-related clinical features and events. We aimed to leverage a new PSC ICD-10 code to characterize racial differences in a nationwide contemporary cohort of patients with PSC. PATIENTS AND METHODS: We used de-identified clinical/administrative data from the Vizient(R) Clinical …
Gut microbiome predictors of advanced therapy response in Crohn's disease: protocol for the OPTIMIST prospective, longitudinal, observational pilot study in Canada
Publication Year: 2025 Source: BMJ Open PMID: 40082000 DOI: 10.1136/bmjopen-2024-094280
INTRODUCTION: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis, is characterised by chronic and relapsing inflammation of the gastrointestinal tract, leading to significant morbidity and reduced quality of life. The global rise in IBD incidence is driven by a complex interplay of genetic, environmental, dietary and microbiome-related …
IL23p19 therapies for moderately-to-severely active ulcerative colitis
Publication Year: 2025 Source: Expert Opin Biol Ther PMID: 40082083
INTRODUCTION: Ulcerative colitis (UC) is a chronic, relapsing and remitting, inflammatory bowel disease. Monoclonal antibodies targeting interleukin (IL)-23p19 have been developed to treat chronic inflammatory diseases mediated by aberrant IL23/Th17 responses, including psoriasis, psoriatic arthritis, and Crohn's disease. More recently, these agents have been evaluated for the treatment of moderately-to-severely …
Promising protective treatment potential of endophytic bacterium Rhizobium aegyptiacum for ulcerative colitis in rats
Publication Year: 2025 Source: J Zhejiang Univ Sci B PMID: 40082206
Ulcerative colitis (UC) is an inflammatory condition of the intestine, resulting from an increase in oxidative stress and pro-inflammatory mediators. In this study, the extract of endophytic bacterium Rhizobium aegyptiacum was prepared for the first time using liquid chromatography-mass spectrometry (LC-MS). In addition, also for the first time, the protective …
Research Progress in Effects of Vermiform Appendix on the Occurrence and Development of Diseases Related to Gut-Brain Axis
Publication Year: 2025 Source: Zhongguo Yi Xue Ke Xue Yuan Xue Bao PMID: 40082232
The gut-brain axis is a bidirectional communication pathway connecting the central nervous system and gastrointestinal tract,playing a key role in the occurrence and development of diseases related to this axis.The vermiform appendix,as a part of the gut that is connected to the cecum,has a unique anatomical location,a rich microbiome,and abundant …
Primary sclerosing cholangitis
Publication Year: 2025 Source: Nat Rev Dis Primers PMID: 40082445
Primary sclerosing cholangitis (PSC) is a chronic biliary inflammation associated with periductular fibrosis of the intrahepatic and extrahepatic bile ducts leading to strictures, bacterial cholangitis, decompensated liver disease and need for liver transplantation. This rare focal liver disease affects all races and ages, with a predominance of young males. There …
Gut commensals-derived succinate impels colonic inflammation in ulcerative colitis
Publication Year: 2025 Source: NPJ Biofilms Microbiomes PMID: 40082467 DOI: 10.1038/s41522-025-00672-3
Gut microbiota-derived metabolites play a crucial role in modulating the inflammatory response in inflammatory bowel disease (IBD). In this study, we identify gut microbiota-derived succinate as a driver of inflammation in ulcerative colitis (UC) by activating succinate-responsive, colitogenic helper T (Th) cells that secrete interleukin (IL)-9. We demonstrate that colitis …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide