Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Correlation Of Fut2 And Fut3 Gene Polymorphisms With Inflammatory Bowel Disease In Guangxi Zhuang Population
Publication Year: 2025 Source: Int J Gen Med PMID: 40046452 DOI: 10.2147/IJGM.S505711
OBJECTIVE: This study aimed to investigate the association between the polymorphisms of the FUT2 gene (rs1047781, rs601338) and the FUT3 gene (rs3745635, rs28362459) with susceptibility to inflammatory bowel disease (IBD) in the Zhuang population of Guangxi. METHODS: Intestinal mucosal tissues were collected from 113 Zhuang patients (41 with Crohn's disease …
Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease
Publication Year: 2025 Source: ACG Case Rep J PMID: 40046648
No Abstract
Fibrinogen-to-albumin ratio: a new biomarker to identify inflammatory bowel disease in active stage
Publication Year: 2025 Source: Front Med (Lausanne) PMID: 40046919 DOI: 10.3389/fmed.2025.1460975
INTRODUCTION: The objective of our study was to externally validate the value of the fibrinogen-to-albumin ratio (FAR), a new biomarker used to identify active inflammatory bowel disease (IBD). MATERIALS AND METHODS: A total of 245 ulcerative colitis (UC) and 543 Crohn's disease (CD) patients were included in our study. Multivariate …
Intestinal luminal anion transporters and their interplay with gut microbiome and inflammation
Publication Year: 2025 Source: Am J Physiol Cell Physiol PMID: 40047092 DOI: 10.1152/ajpcell.00026.2025
The intestine, as a critical interface between the external environment and the internal body, plays a central role in nutrient absorption, immune regulation, and maintaining homeostasis. The intestinal epithelium, composed of specialized epithelial cells, harbors apical anion transporters that primarily mediate the transport of chloride and bicarbonate ions, essential for …
Key roles of milk-derived extracellular vesicles in intestinal tract, with special emphasis on microRNAs in extracellular vesicles
Publication Year: 2025 Source: Crit Rev Food Sci Nutr PMID: 40047253
Studies have indicated that milk extracellular vesicles (EVs) are resistant to both the enzymatic activity of digestive enzymes and the acidic conditions common in the gastrointestinal tract. Thus, the intestinal tract efficiently absorbs and uses these EVs. There is mounting evidence in recent years that microRNAs (miRNAs) found in EVs …
Tea Extracellular Vesicle-Derived MicroRNAs Contribute to Alleviate Intestinal Inflammation by Reprogramming Macrophages
Publication Year: 2025 Source: J Agric Food Chem PMID: 40047388 DOI: 10.1021/acs.jafc.5c01990
The clinical use of conventional medications for inflammatory bowel disease (IBD) is often limited by significant side effects. The extracellular vesicles derived from plant-based diets have shown promise in mitigating disease. Here, we discovered that natural extracellular vesicles from tea (TEVs) can achieve an appropriate transition from proinflammatory (M1) to …
Safety of Advanced Combination Treatment With Selective JAK1 Inhibitors and Biological Therapies in Inflammatory Bowel Diseases: A Real World Experience
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 40047405
This multicenter retrospective study examines 18 patients with difficult-to-treat inflammatory bowel diseases who received advanced combination treatment (ACT) with selective JAK1 inhibitors and biologics, totaling 11.8 patient-years of exposure. Treatment was discontinued in three patients due to adverse events. At 3 months, 77.8% achieved steroid-free clinical remission. The infection incidence …
Phenethyl isothiocyanate ameliorates liver injuries secondary to inflammatory bowel disease
Publication Year: 2025 Source: Food Funct PMID: 40047466 DOI: 10.1039/d4fo04931d
Inflammatory bowel disease (IBD) is often accompanied by secondary liver injury which further evolves into various hepatobiliary disorders. The pathogenesis of secondary liver injury involves many different mechanisms including inflammation, pyroptosis, oxidative stress, and heat shock response. Here, we tested the effect of administration of phenethyl isothiocyanate (PEITC) on secondary …
Probiotic Delivery for Editing of the Gut Microbiota to Mitigate Colitis and Maintain Hepatic Homeostasis Via Gut-Liver Axis
Publication Year: 2025 Source: ACS Nano PMID: 40047584 DOI: 10.1021/acsnano.5c00325
Inflammatory bowel disease (IBD) compromises the intestinal barrier and disrupts gut microbiota, impacting liver function via the gut-liver axis, which in turn influences the intestinal microbiota through lipid metabolites exacerbating IBD. This study introduced a probiotic-based treatment using Lactobacillus acidophilus encapsulated in tungsten ion-loaded mesoporous polydopamine (LA@WMPDA) to ameliorate colitis …
Mirikizumab in the Treatment of Ulcerative Colitis: Initial Real-World Data in a Population from a Large Tertiary Center
Publication Year: 2025 Source: Dig Dis Sci PMID: 40048134
BACKGROUND: Mirikizumab, an anti-p19IL-23 monoclonal antibody, has shown efficacy and safety in treating moderately to severely active ulcerative colitis (UC) in clinical trials. We assessed the effectiveness and safety of mirikizumab for the treatment of UC in a real-world setting. METHODS: We conducted a prospective observational study of adult patients …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide