Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Gut microbiota in Crohn's disease pathogenesis
Publication Year: 2025 Source: World J Gastroenterol PMID: 39958442 DOI: 10.3748/wjg.v31.i6.101266
Inflammatory bowel diseases (IBDs) are classified into two distinct types based on the area and severity of inflammation: Crohn's disease (CD) and ulcerative colitis. In CD, gut bacteria can infiltrate mesenteric fat, causing expansion known as creeping fat, which may limit bacterial spread and inflammation but can promote fibrosis. The …
Evaluating large language models as patient education tools for inflammatory bowel disease: A comparative study
Publication Year: 2025 Source: World J Gastroenterol PMID: 39958450 DOI: 10.3748/wjg.v31.i6.102090
BACKGROUND: Inflammatory bowel disease (IBD) is a global health burden that affects millions of individuals worldwide, necessitating extensive patient education. Large language models (LLMs) hold promise for addressing patient information needs. However, LLM use to deliver accurate and comprehensible IBD-related medical information has yet to be thoroughly investigated. AIM: To …
Patient and physician factors contributing to delays in inflammatory bowel diseases: Enhancing timely diagnosis
Publication Year: 2025 Source: World J Gastroenterol PMID: 39958451
In this article, we comment on the article by Bluthner et al. The article provides a comprehensive analysis of the factors contributing to the late detection of Crohn's disease and ulcerative colitis within a German cohort. It highlights the consequences on patient outcomes, particularly disease progression and the increased risk …
Examining the relationship between secondhand smoke and non-malignant digestive system diseases: Mendelian randomization evidence
Publication Year: 2025 Source: Tob Induc Dis PMID: 39958618
INTRODUCTION: Secondhand smoke (SHS) may exacerbate the global disease burden, particularly in workplace settings. Observational studies have implicated SHS as a risk factor for various non-malignant digestive system diseases (NMDSD), yet establishing a causal relationship remains challenging. Therefore, we conducted a Mendelian randomization (MR) study to explore whether workplace exposure …
Unifying terminology, reporting, and bowel preparation standards in colon capsule endoscopy: Nyborg Consensus
Publication Year: 2025 Source: Endosc Int Open PMID: 39958652
BACKGROUND AND STUDY AIMS: Colon capsule endoscopy (CCE) is becoming increasingly popular in Europe. However, development of quality assurance and standardized terminology has not kept pace with clinical integration of this technology. As a result, there are significant variations in reporting standards, highlighting the need for a standardized terminology and …
Pregnancy-onset inflammatory bowel disease: A case report
Publication Year: 2025 Source: Obstet Med PMID: 39959005
Pregnancy-onset inflammatory bowel disease (POIBD) is a rare diagnosis that has been associated with diagnostic delay and increased risk of hospitalization compared with inflammatory bowel disease diagnosed outside of pregnancy. There is a paucity of data on the clinical presentation and risk factors associated with maternal and fetal outcomes of …
Therapeutic Drug Monitoring for Dose Optimization of Infliximab in Patients With Inflammatory Bowel Disease: An Analysis of Canadian Real-World Data
Publication Year: 2025 Source: Can J Gastroenterol Hepatol PMID: 39959029
Background: Although it is generally believed that infliximab dose optimization in patients with inflammatory bowel disease with low serum infliximab concentration at trough results in increased treatment persistence, empirical data to support this notion are lacking. This study evaluated the association of infliximab therapeutic drug monitoring (TDM) and TDM-associated dose …
Artificial intelligence use for precision medicine in inflammatory bowel disease: a systematic review
Publication Year: 2025 Source: Am J Transl Res PMID: 39959235 DOI: 10.62347/XILL3707
INTRODUCTION: Inflammatory Bowel Disease (IBD), encompassing Crohn's disease and ulcerative colitis, presents significant clinical challenges due to its heterogeneous nature and complex etiology. Recent advancements in biomedical research have enhanced our understanding of IBD's genetic, microbial, and biochemical aspects. However, persistent issues in clinical management, including treatment non-response, surgical interventions, …
Clinical Characteristics and Outcomes of Small Bowel Neoplasms in Crohn's Disease: A Case-Control Study
Publication Year: 2025 Source: Crohns Colitis 360 PMID: 39959612 DOI: 10.1093/crocol/otaf001
BACKGROUND: Patients with Crohn's disease (CD) who have ileal or any small bowel (SB) involvement are at increased risk of developing SB cancer. Due to the rarity of this complication of CD, we aimed to describe the clinical features, presentation, and of small bowel neoplasms (SBN) in patients with CD. …
Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow
Publication Year: 2025 Source: J Inflamm Res PMID: 39959638 DOI: 10.2147/JIR.S503621
BACKGROUND: Inflammatory bowel disease (IBD) comprises a group of autoimmune disorders characterized by chronicity and resistance to cure, with an unknown etiology. Recent studies on the brain-gut axis suggest that the central nervous system (CNS), particularly the hypothalamic-pituitary axis (HPA), may play a crucial role in modulating the immune system …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide