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Primary Sclerosing Cholangitis and Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015822 DOI: 10.1016/j.suc.2024.11.001
Primary sclerosing cholangitis (PSC) is a rare pathology seen in patients with inflammatory bowel disease (IBD), especially ulcerative colitis. PSC increases patients' morbidity and requires the attention of a multidisciplinary team as those patients require frequent colonoscopies and biopsies due to the elevated risk of malignancy, biliary screening and management …
Diagnosis and Treatment of Extraintestinal Manifestations of Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015823 DOI: 10.1016/j.suc.2024.10.003
Inflammatory bowel disease (IBD) is a debilitating disorder that can manifest in many ways and affect multiple organ systems outside the gastrointestinal tract. Extraintestinal manifestations (EIMs) are common in both ulcerative colitis and Crohn's disease and include dermatologic, musculoskeletal, ophthalmologic, and hepatobiliary systems. This study reviews details the most common …
Surgical Management of Pregnant Patients with Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015824 DOI: 10.1016/j.suc.2024.10.004
Pelvic surgery for inflammatory bowel disease (IBD) can reduce fertility. Pregnant women with IBD have higher rates of pregnancy loss and adverse outcomes. Awareness of these factors and adequate multidisciplinary monitoring throughout these high-risk pregnancies is important. Surgeons may need to manage stoma complications, assist in cesarean delivery, or even …
The Fate of the Rectum in Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015825 DOI: 10.1016/j.suc.2024.10.005
For many patients with inflammatory bowel disease (IBD) proctocolitis, proctectomy offers symptom and disease control, albeit at the expense of a potentially morbid proctectomy. There are select situations, however, where definitively leaving an IBD rectum in situ, either in or out of intestinal continuity, may be a suitable alternative to …
Medical Management of Ulcerative Colitis and Crohn's Disease-Strategies for Inducing and Maintaining Remission
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015826
Medical management of ulcerative colitis (UC) and crohn's sisease (CD) is complex. While there is significant overlap in medical therapies used for UC and CD, there remain few distinct differences in their management. The overall goals of therapy are to achieve disease remission, prevent complications, decrease the need for surgical …
Modern Management of Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015828
No Abstract
Comparative Effects of Probiotics and Paraprobiotics Derived from Lactiplantibacillus plantarum, Latilactobacillus sakei, and Limosilactobacillus reuteri in a DSS-Induced Ulcerative Colitis Mouse Model
Publication Year: 2025 Source: J Microbiol Biotechnol PMID: 40016142
Live biotherapeutic products, represented by probiotics with disease-mitigating or therapeutic effects, face significant limitations in achieving stable colonization in the gut through oral administration. However, paraprobiotics, which consist of dead or inactivated microbial cells derived from probiotics, can provide comparable health benefits while overcoming the limitations associated with live biotherapeutic …
Patient and Health Care Professional Perspectives on the Burden and Daily Life Impact of Ulcerative Colitis and Crohn's Disease: Results from the Japanese CONFIDE Study
Publication Year: 2025 Source: Adv Ther PMID: 40016440
INTRODUCTION: The global Communicating Needs and Features of Inflammatory Bowel Disease Experiences (CONFIDE) study aimed to evaluate the impact of ulcerative colitis (UC)- and Crohn's disease (CD)-related symptoms on patients' lives and elucidate communication gaps between patients and health care professionals (HCPs). We report the findings from the study in …
Comparing Long-Term Infliximab Persistence Following a Switch to a Biosimilar in Patients With Inflammatory Bowel Disease: No Cause for Concern
Publication Year: 2025 Source: J Gastroenterol Hepatol PMID: 40016953 DOI: 10.1111/jgh.16916
No Abstract
Pediatric Crohn Disease Presenting as Isolated Acute Upper-GI Bleed: A Case Report
Publication Year: 2025 Source: Am J Case Rep PMID: 40017015 DOI: 10.12659/AJCR.946099
BACKGROUND The incidence of Crohn's disease (CD) has increased worldwide. Although common presenting symptoms of CD in children include abdominal pain, diarrhea, and rectal bleeding, it can also present atypically and can have extraintestinal manifestations. Isolated upper-gastrointestinal bleed as the only manifestation of CD with ileocolonic involvement is rare. CASE …
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