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The Pathogenesis of Inflammatory Bowel Diseases
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015812 DOI: 10.1016/j.suc.2024.10.008
Inflammatory bowel diseases (IBDs) are relapsing, remitting inflammatory diseases of the intestinal tract. Familial aggregation and genome-wide association studies revealed susceptibility variants that point toward a combination of innate immune and adaptive immune dysregulation that in concert with environmental factors, such as our microbiome, can initiate and perpetuate inflammation. Innate …
Diagnosis and Differentiation of Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015813
No Abstract
The Essential Role of Imaging in the Diagnosis, Characterization, and Treatment of Patients with Crohn's Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015814
Imaging is essential in assessing patients with Crohn's disease, and it provides important and complementary information to the clinical and endoscopic findings. Patients can be accurately phenotyped and complications identified.
Operative Management of Small and Large Bowel Crohn's Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015815
The majority of patients with Crohn's disease, despite an ever-increasing number of advanced therapies, require abdominal surgery during their lifetime. In this review article, the authors provide a comprehensive overview of abdominal surgery for Crohn's disease, with an evidence-based focus on surgery for upper gastrointestinal Crohn's disease, bowel-preserving surgery with …
Operative Management of Perianal Crohn's Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015816
No Abstract
Surgical Management of Ulcerative Colitis
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015817
No Abstract
Emerging Technologies in Inflammatory Bowel Disease: A Minireview on Future Treatment Modalities
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015818 DOI: 10.1016/j.suc.2024.09.004
Inflammatory bowel disease (IBD) can present as either Crohn's disease or ulcerative colitis. Both phenotypes are inflammatory conditions of the gastrointestinal tract. Despite scientific advances, the overall incidence and morbidity of IBD continues to increase worldwide. Fortunately, we continue to develop novel therapies, in hopes of providing safer, more effective …
Surveillance and Management of Dysplasia and Malignancy in Inflammatory Bowel Disease
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015819
The paradigm for surveilling and managing inflammatory bowel disease-associated colorectal dysplasia has changed as high-definition colonoscopy and chromoendoscopy have significantly improved the visualization of dysplasia, and endoscopic mucosal resection has made more lesions endoscopically resectable. However, these patients are at high risk of recurrent dysplasia and cancer and require intensive …
Operative Management of Inflammatory Bowel Disease in Children
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015820 DOI: 10.1016/j.suc.2024.10.001
Inflammatory bowel disease (IBD) encompasses a spectrum of chronic, idiopathic, and progressive inflammatory conditions of the gastrointestinal tract, with Crohn's disease and ulcerative colitis comprising the majority. Both conditions have distinct pathophysiological and clinical characteristics but share common immune-mediated mechanisms. Specific facets of IBD and its management in the pediatric …
Management of J-pouch Complications
Publication Year: 2025 Source: Surg Clin North Am PMID: 40015821
No Abstract
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