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Validity and Reliability of the Self-Care of Chronic Illness Inventory in Patients Living With Inflammatory Bowel Disease

Publication Year: 2025 Source: J Clin Nurs PMID: 40033448 DOI: 10.1111/jocn.17712

AIM: To test the psychometric properties of the Self-Care of Chronic Illness Inventory (SC-CII) in patients living with inflammatory bowel disease (IBD). DESIGN: A cross-sectional, multicenter study. METHODS: A total of 452 IBD patients were recruited from nine centres across Italy. Participants completed the SC-CII, the Self-Care Self-Efficacy Scale (SCSES), …

The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae in the inflamed gut

Publication Year: 2025 Source: Virulence PMID: 40033924 DOI: 10.1080/21505594.2025.2474185

The mammalian intestine is a major site of colonization and a starting point of severe infections by Klebsiella pneumoniae. Inflammatory bowel disease (IBD) is an inflammatory disorder of the gut, and host-derived nitrate in IBD confers a luminal growth advantage upon Escherichia coli and Salmonella typhimurium through nitrate respiration in …

Alterations in ether phospholipids metabolism activate the conserved UPR-Xbp1- PDIA3/ERp60 signaling to maintain intestinal homeostasis

Publication Year: 2025 Source: iScience PMID: 40034858

Intestinal epithelium regeneration and homeostasis must be tightly regulated. Alteration of epithelial homeostasis is a major contributing factor to diseases such as colorectal cancer and inflammatory bowel diseases. Many pathways involved in epithelial regeneration have been identified, but more regulators remain undiscovered. Metabolism has emerged as an overlooked regulator of …

Adipose-Derived Mesenchymal Stem Cell Exosomes Encapsulating siIL1R2 Facilitate the Repair of DSS-Induced Intestinal Mucosal Injury

Publication Year: 2025 Source: Immunol Invest PMID: 40035289

BACKGROUND: Interleukin-1 receptor 2 (IL1R2) and C-C motif chemokine receptor 2 (CCR2) as critical mediators of immune modulation and inflammation. This study aims to evaluate their functions in dextran sulfate sodium (DSS)-induced intestinal injury. METHODS: A DSS-induced intestinal injury model was established in C57BL/6 mice. Pharmacological inhibitors targeting IL1R2 or …

Clinical nutrition in gastrointestinal diseases: an up-to-date clinical practice guideline

Publication Year: 2025 Source: Pol Arch Intern Med PMID: 40035369

This paper presents updated recommendations on clinical nutrition in gastrointestinal diseases, developed by the Clinical Nutrition and Metabolism Section of the Polish Society of Gastroenterology. Their aim is to provide clinicians with comprehensive and up-to-date data on the diagnosis and management of malnutrition in various gastrointestinal conditions, including inflammatory bowel …

Editorial: Can We Modify the Development and Disease Course of Inflammatory Bowel Disease by Diet?

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 40035404

No Abstract

Editorial: Can We Modify the Development and Disease Course of Inflammatory Bowel Disease by Diet? Author's Reply

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 40035417

No Abstract

Increasing Rate of Hospitalization for Inflammatory Bowel Disease Is an Age-Related Effect: A Canadian Population Study

Publication Year: 2025 Source: Am J Gastroenterol PMID: 40035436 DOI: 10.14309/ajg.0000000000003385

INTRODUCTION: To understand trends in the risk of all-cause hospitalization for individuals with inflammatory bowel disease, we explored age, period, and cohort effects in Canada. METHODS: Repeated cross-sectional survey data from the 2005-2014 Canadian Community Health Survey linked to the Discharge Abstract Database to capture the all-cause hospitalization within 3 …

Synbiotic yacon juice fermented by Lactiplantibacillus plantarum QS7T attenuates dextran sodium sulfate-induced ulcerative colitis in mice

Publication Year: 2025 Source: J Food Sci PMID: 40035703

Ulcerative colitis (UC) is a prevalent inflammatory bowel disease associated with abnormal immune responses to commensal bacteria. The study investigated the effects of synbiotic yacon juice fermented by Lactiplantibacillus plantarum QS7T (FYJ) on ameliorating UC and modulating gut microbiota in a dextran sodium sulfate (DSS)-induced colitis mouse model. FYJ intervention …

Chrysin ameliorates dextran sulfate-induced ulcerative colitis in mice by modulating inflammation and gut microbiota

Publication Year: 2025 Source: Int J Colorectal Dis PMID: 40035853 DOI: 10.1007/s00384-025-04843-8

BACKGROUND: Inflammatory bowel disease (IBD) encompasses chronic inflammation of the colon and rectum, posing significant health challenges. Previous studies have shown potential therapeutic effects of natural compounds on IBD. Chrysin, a naturally occurring flavonoid, has been suggested to modulate inflammatory pathways and gut microbiota, but its comprehensive impact on ulcerative …

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