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IBD Matchmaking: Rational Combination Therapy

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39025253 DOI: 10.1016/j.cgh.2024.05.051

A growing number of patients with Crohn's disease and ulcerative colitis have disease that is refractory to multiple advanced therapies, have undergone multiple surgeries, and require further treatment options. For this reason, there has been increasing use of multiple simultaneous advanced targeted therapies. Although the knowledge on combined advanced targeted …

Mucosal Healing With Vedolizumab in Patients With Chronic Pouchitis: EARNEST, a Randomized, Double-Blind, Placebo-Controlled Trial

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39025255

No Abstract

Filgotinib induction-study baseline characteristics of patients with ulcerative colitis who achieve sustained corticosteroid-free remission: post hoc analysis of the phase 2b/3 SELECTION study

Publication Year: 2025 Source: Intest Res PMID: 39026439 DOI: 10.5217/ir.2024.00007

BACKGROUND/AIMS: Obtaining and maintaining corticosteroid-free remission are important goals of treatment for ulcerative colitis (UC). Characteristics associated with achieving corticosteroid-free remission were assessed in filgotinib-treated patients in SELECTION, a 58-week, phase 2b/3 trial in moderately to severely active UC. METHODS: This post hoc analysis used data from filgotinib-treated patients receiving …

Volumetric measurement of terminal ileal Crohn's disease by magnetic resonance enterography: a feasibility study

Publication Year: 2025 Source: Eur Radiol PMID: 39028375

No Abstract

High Healthcare Costs in Childhood Inflammatory Bowel Disease: Development of a Prediction Model Using Linked Clinical and Health Administrative Data

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39028498 DOI: 10.1093/ibd/izae148

BACKGROUND: The incidence of pediatric-onset inflammatory bowel disease (IBD) and the costs of caring for individuals with IBD are both increasing. We calculated the direct healthcare costs of pediatric IBD in the first year after diagnosis and developed a model to predict children who would have high costs (top 25th …

Diagnostic and Therapeutic Challenges in Severe Peristomal Pyoderma Gangrenosum

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39028852

No Abstract

Evaluation of the sensitivity and specificity of sigmoidoscopy in comparison to colonoscopy regarding the detection of intestinal inflammatory activity in the follow-up of patients with ulcerative colitis

Publication Year: 2025 Source: Gastroenterol Hepatol PMID: 39029790

No Abstract

Single-Center Mid-term Experience with E-Liac Branched Device from Artivion®

Publication Year: 2025 Source: Ann Vasc Surg PMID: 39029895 DOI: 10.1016/j.avsg.2024.05.042

BACKGROUND: The use of iliac branch device (IBD) is increasing due to the less invasive character and accumulated experience of physicians in this endovascular technique. Clinical data regarding the E-liac stent graft from Artivion(R), however, are scarce. This study shows the mid-term outcomes of the E-liac stent graft from a …

Cannabinoids for Inflammatory Bowel Disease: A Scoping Review

Publication Year: 2025 Source: Cannabis Cannabinoid Res PMID: 39029906 DOI: 10.1089/can.2024.0061

Purpose: Inflammatory bowel disease (IBD) has two main variants, ulcerative colitis (UC) and Crohn's disease (CD), which are characterized by a cycle of remission and relapse. The aim of this scoping review is to understand the landscape of unprescribed and prescribed cannabis use among patients with IBD and investigate objective …

Comparative outcomes of endoscopic mucosal resection for laterally spreading lesions in inflammatory bowel disease

Publication Year: 2025 Source: Endoscopy PMID: 39029912 DOI: 10.1055/a-2369-7980

BACKGROUND: The role of endoscopic mucosal resection (EMR) for laterally spreading lesions (LSLs) in inflammatory bowel disease (IBD) remains controversial despite its effectiveness in the general population. We aimed to characterize outcomes of EMR for IBD-associated LSLs compared with controls without IBD. METHODS: We performed a retrospective observational cohort study …

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