Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Young Adult Patients With Paediatric-Onset Inflammatory Bowel Disease Have a Higher Educational Level and a Higher Employment Rate Than the General Population
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39945233
BACKGROUND & AIMS: There are few published data on the impact of paediatric-onset inflammatory bowel diseases on education and employment. The objective of the present cross-sectional study was to assess the educational level and occupational status of adult patients with paediatric-onset inflammatory bowel diseases from the EPIMAD Registry. METHODS: The …
Serum Biomarkers of Extracellular Matrix Remodeling in Ulcerative Colitis-One Step Closer to Fibrosis Biomarkers in Inflammatory Bowel Disease
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39945303
No Abstract
Real-world prevalence of potential drug-drug interactions associated with oral advanced therapies indicated for ulcerative colitis
Publication Year: 2025 Source: Curr Med Res Opin PMID: 39945336
OBJECTIVE: To describe potential drug-drug interactions (DDIs) with oral advanced therapies among patients with ulcerative colitis (UC) and characterize clinical assessments before ozanimod initiation. METHODS: Adults with UC were selected from the Merative MarketScan Commercial Database (01 January 2018-31 January 2023); the index date was the most recent UC diagnosis. …
Inflammatory Bowel Disease, Periconceptional Disease Activity, and Risk of Major Congenital Anomalies: A Nationwide Cohort Study
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39945675 DOI: 10.14309/ajg.0000000000003306
INTRODUCTION: It is uncertain whether the risk of major congenital anomalies (mCAs) is increased in children of women with inflammatory bowel disease (IBD). METHODS: We aimed to determine the risk of mCAs in a Swedish nationwide cohort of 13,131 singleton live births from 1997 to 2020 to women with IBD …
Perioperative enhanced recovery program implementation improves clinical outcomes in patients with ulcerative colitis after total proctocolectomy with ileal pouch-anal anastomosis
Publication Year: 2025 Source: Int J Colorectal Dis PMID: 39945848
BACKGROUND: Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is widely regarded as a definitive surgical option for managing ulcerative colitis (UC). Enhanced recovery programs (ERP) have shown potential in better outcomes following surgery; however, their perioperative benefits in UC patients undergoing IPAA remain insufficiently investigated. METHODS: This study included UC …
Prevalence, Clinical Features, and Extraintestinal Manifestations in Patients with Familial Inflammatory Bowel Diseases
Publication Year: 2025 Source: Dig Dis Sci PMID: 39946067 DOI: 10.1007/s10620-025-08868-5
BACKGROUND: A positive family history is considered the strongest recognizable risk factor for developing inflammatory bowel diseases (IBD) and is present in 8-12% of cases. AIMS: To determine the prevalence of familial IBD and also to compare the clinical characteristics and extraintestinal manifestations between familial and sporadic cases. METHODS: We …
Effect of Anti-TNF Monoclonal Antibody on Enteric Neurons and Enteric Glial Cells in Experimental Colitis
Publication Year: 2025 Source: Dig Dis Sci PMID: 39946069 DOI: 10.1007/s10620-025-08872-9
BACKGROUND: Inflammatory bowel diseases (IBD) affect both enteric neurons and enteric glia, with tumor necrosis factor-alpha (TNF-alpha) playing a role as an inflammatory mediator. AIMS: Analyze the effects of the anti-TNF monoclonal antibody on the myenteric plexus in an experimental model of colitis. METHODS: C57BL/6 mice received 3% dextran sodium …
Switching to Subcutaneous Infliximab Maintenance Therapy Is Effective in Patients with Inflammatory Bowel Disease
Publication Year: 2025 Source: Dig Dis Sci PMID: 39946070 DOI: 10.1007/s10620-025-08876-5
BACKGROUND: Recent studies suggest that subcutaneous infliximab is effective and safe for treating patients with inflammatory bowel disease. Real-world studies with larger cohorts are needed to confirm the efficacy of subcutaneous treatment. AIMS: The aim was to assess real-world treatment persistence, clinical outcomes, infliximab concentrations, and treatment safety after switching …
Mitochondrial Dysfunction: Unraveling the Elusive Biology Behind Anti-TNF Response During Ulcerative Colitis
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39946175
BACKGROUND: Recent studies hint at mitochondrial genes influencing UC patient response to anti-TNF treatment. We evaluated this hypothesis by following a targeted strategy to identify gene expression that captures the relationship between mitochondrial dysregulation and response to treatment. Our objective was to initially examine this relationship in colon samples and …
Role of declined electrogenic Na(+)/HCO(3)(-) cotransporter NBCe1 in mucus barrier impairment and colonic inflammation
Publication Year: 2025 Source: Int Immunopharmacol PMID: 39946770 DOI: 10.1016/j.intimp.2025.114282
BACKGROUND: Electrogenic Na(+)/HCO(3)(-) co-transporter 1 (NBCe1) plays a pivotal role in epithelial bicarbonate transport involved in the maintenance of the intestinal mucus barrier. However, the specific role of NBCe1 in colitis remains unknown. METHODS: NBCe1 was identified by bioinformatics analysis methods including GO/KEGG/GSEA, protein-protein interaction (PPI) network analysis, immune infiltration …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide