Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Fecal calprotectin from ileostomy output in patients with Crohn's disease
Publication Year: 2025 Source: BMC Gastroenterol PMID: 39948457
BACKGROUND: Fecal calprotectin (FC) is a reliable biomarker widely used for assessing disease activity and postoperative monitoring in patients with Crohn's disease (CD); however, its efficacy in patients with an ileostomy is poorly understood. Our study evaluated whether FC from the ileostomy output can be used to predict postoperative small …
IgG-seq identifies immune-reactive enteric bacteria in Crohn's disease with spondyloarthritis
Publication Year: 2025 Source: Gut Microbes PMID: 39949039
Joint inflammation is the most common extraintestinal manifestation of Crohn's disease (CD). Although alterations in the enteric microbiota are described in CD with spondyloarthritis (CD-SpA), it is not known whether distinct taxa serve as markers for clinical subtypes of axial (AxSpA) or peripheral SpA (pSpA) in CD. Moreover, it is …
B-cell Acute Lymphoblastic Leukemia in a Patient With Crohn's Disease After Anti-TNF-Alpha Treatment
Publication Year: 2025 Source: Cureus PMID: 39949431 DOI: 10.7759/cureus.77400
This case report details a patient with Crohn's disease (CD) who developed acute lymphoblastic leukemia (ALL) 16 years after their initial diagnosis. Various immunosuppressive therapies used in the treatment included azathioprine, infliximab and, for a short period, vedolizumab and steroids for CD and hyper-CVAD chemotherapy for leukemia. The association between …
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway
Publication Year: 2025 Source: Front Immunol PMID: 39949764 DOI: 10.3389/fimmu.2025.1537651
INTRODUCTION: Ulcerative colitis (UC) is a global gastrointestinal disease, which is mainly caused by both dysfunctional epithelial barrier and inflammation response. Iron is a critical fundamental element for both the maintenance of homeostasis and the mediation of inflammation in many tissues. However, the role and mechanism of iron in the …
Locus of Control in Patients with Mild-to-Moderate Ulcerative Colitis: A Comparative Study
Publication Year: 2025 Source: Ann Neurosci PMID: 39949797
BACKGROUND: Ulcerative colitis (UC) is a chronic condition characterised by inflammation of the large intestine, causing an impact on a patient's psychological well-being. Earlier research has demonstrated the important role of locus of control (LOC) in facing the challenges brought out by many gastrointestinal system diseases. PURPOSE: The aim of …
Microplastic effects on mouse colon in normal and colitis conditions: A literature review
Publication Year: 2025 Source: PeerJ PMID: 39950042
BACKGROUND: Taking into account the global spread of microplastic (MP) pollution, the problem of the MP impact on human health is relevant. MP enters the organism predominantly with water and food, and is mostly detected in the large intestine. Therefore, the connection between MP pollution and the increase in colitis …
Do Bowel Disorders Affect Holmium Laser Enucleation of Prostate Outcomes? A Retrospective Cohort Study
Publication Year: 2025 Source: Ther Adv Urol PMID: 39950067 DOI: 10.1177/17562872251317918
OBJECTIVES: To review outcomes for patients with irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD) who undergo holmium laser enucleation of prostate (HoLEP) for bothersome urinary symptoms related to benign prostatic hyperplasia (BPH). METHODS: We performed a retrospective review of patients who had undergone HoLEP by a single surgeon …
Geographic and Temporal Patterns in Biologic Prescriptions for Inflammatory Bowel Diseases in the Public Healthcare System in Brazil: An Ecological Study
Publication Year: 2025 Source: Pharmacoepidemiol Drug Saf PMID: 39950239 DOI: 10.1002/pds.70114
PURPOSE: To analyze the geographic and temporal patterns of biologic prescriptions for inflammatory bowel disease (IBD) in Brazil's public national unified health system (SUS). METHODS: This ecological study used data from patients with IBD in the SUS Outpatient Information System between 2008 and 2022. Prais-Winsten regression was used to estimate …
[MR Imaging of ano-perineal fistulas]
Publication Year: 2025 Source: Rev Med Liege PMID: 39950529
The frequency of occurrence of ano-perineal fistulas, especially in the context of inflammatory bowel diseases, makes them a subject of growing interest, mainly because of the discomfort and medico-social impact they induce in patients who carry them. Their treatment depends on their extent and potential for evolution. MRI appears as …
Successful Use of Anakinra in a Patient with IL-10R Beta Deficiency: A Case Report
Publication Year: 2025 Source: Pediatr Allergy Immunol Pulmonol PMID: 39950990 DOI: 10.1089/ped.2024.0116
Background: Interleukin-10 (IL-10) is a crucial anti-inflammatory cytokine essential for maintaining immune homeostasis, particularly in the gastrointestinal system. Defects in the IL-10 signaling pathway, including mutations in interlaukin-10 receptor (IL-10R) beta, have been implicated in early-onset inflammatory bowel disease (IBD), often resistant to conventional treatments. Case Presentation: We report a …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide