Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Potential of Glycyrrhiza in the prevention of colitis-associated colon cancer
Publication Year: 2025 Source: Fitoterapia PMID: 39842555
ETHNOPHARMACOLOGICAL RELEVANCE: Glycyrrhiza, a legume native to the Mediterranean region, has a long history of ethnomedicinal use in China. Due to its antiviral, antibacterial, anti-inflammatory, antioxidant, antitumor, anti-ulcer, and hepatoprotective properties, Glycyrrhiza is widely utilized in the treatment of gastrointestinal disorders. THE AIM OF THE REVIEW: The specific mechanisms of …
TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice
Publication Year: 2025 Source: Mucosal Immunol PMID: 39842611 DOI: 10.1016/j.mucimm.2025.01.003
Intestinal immune homeostasis relies on intestinal epithelial cells (IECs), which provide an efficient barrier, and warrant a state of tolerance between the microbiome and the mucosal immune system. Thus, proper epithelial microbial sensing and handling of microbes is key to preventing excessive immunity, such as seen in patients with inflammatory …
Postoperative outcomes of a pelvic pouch procedure: Lessons learned over 40 years among 5070 patients
Publication Year: 2025 Source: J Gastrointest Surg PMID: 39842768 DOI: 10.1016/j.gassur.2024.101938
BACKGROUND: This study aimed to report the experience over 40 years and outcomes of 5070 patients who underwent a pelvic pouch procedure. METHODS: A retrospective analysis of a prospectively maintained ileal pouch-anal anastomosis (IPAA) database (1983-2022) was performed. Patients were stratified based on the following diagnoses: ulcerative colitis (UC), indeterminate …
Chronic enteropathy associated with SLCO2A1 from North India: a rare monogenic condition mimicking Crohn's disease
Publication Year: 2025 Source: BMJ Case Rep PMID: 39842898
Multiple chronic ulcers of the small intestine are primarily attributed to Crohn's disease. Other differential diagnoses include rare monogenic disorders caused by mutations in PLA2G4A and SLCO2A1, the latter responsible for chronic enteropathy associated with SLCO2A1 (CEAS), a condition mainly reported in Asian patients. We present the case of a …
Functional chitosan/HP-β-CD hydrogel for targeted co-delivery of Rhubarb-derived nanovesicles and kaempferol for alleviating ulcerative colitis
Publication Year: 2025 Source: Carbohydr Polym PMID: 39843107
No Abstract
CD45-PET is a robust, non-invasive tool for imaging inflammation
Publication Year: 2025 Source: Nature PMID: 39843738
Imaging inflammation holds immense potential for advancing the diagnosis, treatment and prognosis of many conditions(1-3). The lack of a specific and sensitive positron emission tomography (PET) probe to detect inflammation is a critical challenge. To bridge this gap, we present CD45-PET imaging, which detects inflammation with exceptional sensitivity and clarity …
Key Themes in the Care of Inflammatory Bowel Diseases Among Immigrant Populations: A Systematic Review
Publication Year: 2025 Source: Dig Dis Sci PMID: 39843786 DOI: 10.1007/s10620-024-08801-2
BACKGROUND: The care of inflammatory bowel disease (IBD) requires special attention among immigrants due to different disease incidence, phenotype, and risk profiles. We aimed to highlight key themes among existing literature to inform equitable care in all immigrants living with IBD. METHODS: A systematic literature search was conducted in MEDLINE, …
Maternal Smoking Around Birth Is a Risk Factor for Gastrointestinal Diseases in Offspring: A Mendelian Randomization Study
Publication Year: 2025 Source: Dig Dis Sci PMID: 39843788 DOI: 10.1007/s10620-025-08854-x
BACKGROUND: The effect of maternal smoking around birth (MSAB) on gastrointestinal (GI) diseases in the offspring is still not fully understood. AIM: We conducted a rigorous Mendelian randomization (MR) study to examine the association between MSAB and 24 GI diseases in offspring. METHODS: Single nucleotide polymorphisms (SNPs) associated with MSAB …
Delays in Initiating Biologic Therapy in Patients with Inflammatory Bowel Disease-Perception and Reality
Publication Year: 2025 Source: Dig Dis Sci PMID: 39843791 DOI: 10.1007/s10620-025-08855-w
No Abstract
Protective effect of low-dose lactulose in dextran sulfate sodium induced ulcerative colitis model of rats
Publication Year: 2025 Source: Sci Rep PMID: 39843913
Although low-dose lactulose has shown a good theoretical foundation for the treatment of ulcerative colitis (UC) in previous studies, the exact effects and mechanism remain unclear. The rats were randomly distributed into 5 groups, i.e., normal drinking water was provided for an initial 14 days in blank control group, 4% …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide