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Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway
Publication Year: 2025 Source: Front Pharmacol PMID: 39845801
No Abstract
Ischemic colitis presenting as a colonic mass: a case report and diagnostic challenges
Publication Year: 2025 Source: Front Med (Lausanne) PMID: 39845835 DOI: 10.3389/fmed.2024.1503190
Ischemic colitis (IC) is a multifaceted condition that often manifests with nonspecific symptoms such as abdominal pain and bloody diarrhea, particularly in older adults with vascular risk factors. Diagnosis is supported by elevated levels of white blood cells, lactate, and C-reactive protein (CRP). Computed tomography (CT) imaging typically reveals wall …
Diagnosis and management of de novo inflammatory bowel disease after solid organ transplantation in the era of biologic therapy: a case series
Publication Year: 2025 Source: Front Transplant PMID: 39846032 DOI: 10.3389/frtra.2024.1483943
INTRODUCTION: The clinical characteristics of de novo inflammatory bowel disease (dnIBD) diagnosed after solid organ transplant (SOT) are not well-described, particularly since the advent of biologic therapy for treatment of IBD. METHODS: We conducted a single-center, retrospective review of SOT recipients between 2010 and 2022 at the University of Minnesota …
[Gastroenterology and hepatology : what's new in 2024]
Publication Year: 2025 Source: Rev Med Suisse PMID: 39846097
The year 2024 was rich in developments in the field of hepatology, gastroenterology, and interventional endoscopy. New molecules have been developed for the treatment of metabolic steatohepatitis, primary biliary cirrhosis, and inflammatory bowel diseases. Technological progress now makes it possible to perform screening measurements for portal hypertension directly under echo-endoscopic …
Outcomes after surgical repair of primary parastomal hernia
Publication Year: 2025 Source: Hernia PMID: 39847107 DOI: 10.1007/s10029-025-03267-1
PURPOSE: Parastomal hernia is a frequent complication after stoma construction, with increasing incidence over time. Surgical repair is reported with a high recurrence rate and the evidence on the topic is limited. We conducted a retrospective study to evaluate the incidence of recurrence after parastomal hernia repair and assessed the …
Clinical and Imaging Characteristics of Posterior Scleritis in Children
Publication Year: 2025 Source: Ocul Immunol Inflamm PMID: 39847430
BACKGROUND: Posterior scleritis (PS) is a rare phenotype of scleritis. Comprehensive epidemiological studies on PS in children are limited. We aimed to report on its clinical and imaging features in one of the largest pediatric series to date. METHODS: Retrospective review of medical files. RESULTS: Included were 12 children (7 …
The impact of advanced medical therapies on time to resection and colorectal cancer outcomes in ulcerative colitis patients undergoing colectomy
Publication Year: 2025 Source: J Crohns Colitis PMID: 39847462
BACKGROUND: We aimed to evaluate the impact of advanced medical therapies (biologicals and small molecules) on time to colectomy and oncological outcomes in ulcerative colitis (UC). METHODS: This cohort study included UC patients who underwent colectomy between 2003 and 2022 at 2 referral centers in Belgium and the Netherlands. Exposure …
Pharmacology of Intestinal Inflammation and Repair
Publication Year: 2025 Source: Annu Rev Pharmacol Toxicol PMID: 39847467
Chronic inflammation is a common trait in the pathogenesis of several diseases of the gut, including inflammatory bowel disease and celiac disease. Control of the inflammatory response is crucial in these pathologies to avoid tissue destruction and loss of intestinal function. Over the last 50 years, the identification of the …
Incidence and Risk Factors for Nonreversal of Stoma in Patients With Crohn's Disease: A Single-Center Study
Publication Year: 2025 Source: Dis Colon Rectum PMID: 39847799
No Abstract
Biologic Therapy Is Associated With Improved Oncologic Outcomes in Crohn's Disease-Associated Colorectal Cancer
Publication Year: 2025 Source: Dis Colon Rectum PMID: 39847800
No Abstract
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