Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Assessment tools for transition readiness in adolescents with inflammatory bowel disease: A scoping review
Publication Year: 2025 Source: PLoS One PMID: 39774476
BACKGROUND: Assessing the level of transition readiness in adolescents with inflammatory bowel disease is crucial; however, standardized research tools are lacking. This study aimed to map transition readiness assessment tools for adolescents with inflammatory bowel disease and determine their suitability. METHODS: A literature review following the Arksey and O'Malley scoping …
What Gastroenterologists Should Know About Microplastics and Nanoplastics
Publication Year: 2025 Source: J Clin Gastroenterol PMID: 39774594
Global production and widespread use of plastics are increasing dramatically. With current limited recycling and recovery options, microplastics and nanoplastics (MNPs) persist in the natural environment. Due to their ubiquity, human exposure to MNPs is inevitable. In addition to their inherent toxic effects, MNPs can adsorb harmful contaminants and act …
Use of Artificial Intelligence in Lower Gastrointestinal and Small Bowel Disorders: An Update Beyond Polyp Detection
Publication Year: 2025 Source: J Clin Gastroenterol PMID: 39774596
Machine learning and its specialized forms, such as Artificial Neural Networks and Convolutional Neural Networks, are increasingly being used for detecting and managing gastrointestinal conditions. Recent advancements involve using Artificial Neural Network models to enhance predictive accuracy for severe lower gastrointestinal (LGI) bleeding outcomes, including the need for surgery. To …
Ramadan intermittent fasting for patients with gastrointestinal and hepatobiliary diseases: practical guidance for health-care professionals
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39805284
Ramadan intermittent fasting can pose challenges and risks for some groups of patients. Based on a narrative literature review and our clinical expertise, we provide practical guidance for clinicians managing patients with gastrointestinal and hepatobiliary conditions who wish to fast during Ramadan. Following the established International Diabetes Federation and Diabetes …
Peripheral blood immune cells from individuals with Parkinson's disease or inflammatory bowel disease share deficits in iron storage and transport that are modulated by non-steroidal anti-inflammatory drugs
Publication Year: 2025 Source: Neurobiol Dis PMID: 39805368 DOI: 10.1016/j.nbd.2025.106794
Parkinson's Disease (PD) is a multisystem disorder in which dysregulated neuroimmune crosstalk and inflammatory relay via the gut-blood-brain axis have been implicated in PD pathogenesis. Although alterations in circulating inflammatory cytokines and reactive oxygen species (ROS) have been associated with PD, no biomarkers have been identified that predict clinical progression …
[Crohn's disease complicated with squamous cell carcinoma originating from an enterocutaneous fistula:a case report]
Publication Year: 2025 Source: Nihon Shokakibyo Gakkai Zasshi PMID: 39805623
This case report describes Crohn's disease complicated by squamous cell carcinoma in an enterocutaneous fistula. A 48-year-old male patient was diagnosed with Crohn's disease 24 years ago and has undergone five surgical operations. An enterocutaneous fistula originated from the midline abdominal wound 11 years after the onset. Azathioprine was initiated …
SLC6A14 as a Key Diagnostic Biomarker for Ulcerative Colitis: An Integrative Bioinformatics and Machine Learning Approach
Publication Year: 2025 Source: Biochem Genet PMID: 39806040
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by intestinal inflammation and autoimmune responses. This study aimed to identify diagnostic biomarkers for UC through bioinformatics analysis and machine learning, and to validate these findings through immunofluorescence staining of clinical samples. Differential expression analysis was conducted on expression profile …
MAPK signaling mediated intestinal inflammation induced by endoplasmic reticulum stress and NOD2
Publication Year: 2025 Source: Mol Cell Biochem PMID: 39806198 DOI: 10.1007/s11010-025-05212-3
Endoplasmic reticulum (ER) stress is crucially involved in inflammatory bowel disease (IBD), but the mechanisms remain incompletely understood. This study aimed to elucidate how ER stress promotes inflammation in IBD. ER stress marker Grp78 and NOD2 in colon tissues of Crohn's disease (CD) patients and IBD model mice were detected …
Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation
Publication Year: 2025 Source: J Transl Med PMID: 39806416 DOI: 10.1186/s12967-024-05873-6
BACKGROUND: The conversion of primary bile acids to secondary bile acids by the gut microbiota has been implicated in colonic inflammation. This study investigated the role of gut microbiota related bile acid metabolism in colonic inflammation in both patients with inflammatory bowel disease (IBD) and a murine model of dextran …
hsa_circ_0015388 Reduces Macrophage Derived Reactive Oxygen Species in Crohn's Disease
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39807080
BACKGROUND: Crohn's disease (CD) is a refractory inflammatory bowel disease with an unclear etiology. CircularRNA (circRNA) has been highlighted as a novel class of functional noncoding RNAs associated with the pathogenesis of various diseases. However, the functions of circRNA in CD remain unclear. METHODS: Biopsies were obtained from noninflammatory sites …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide