Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Microvascular Damage in the Deep Mucosal Lamina Propria Triggers the Onset of Colitis in Dextran Sulfate Sodium-induced Colitis in Mice
Publication Year: 2025 Source: In Vivo PMID: 40578998
BACKGROUND/AIM: Dextran sulfate sodium (DSS) is employed to induce colitis in mice for studying ulcerative colitis (UC), an inflammatory bowel disease. However, the precise mechanism underlying its action remains unclear. Microcirculatory issues in the colonic mucosa contribute to DSS-induced colitis; however, early structural changes in the local vascular system have …
Insights on regional and demographic patterns of IBD among young women: A comment
Publication Year: 2025 Source: Dig Liver Dis PMID: 40579069 DOI: 10.1016/j.dld.2025.04.034
No Abstract
[Ecliptasaponin A ameliorates DSS-induced colitis in mice by suppressing M1 macrophage polarization via inhibiting the JAK2/STAT3 pathway]
Publication Year: 2025 Source: Nan Fang Yi Ke Da Xue Xue Bao PMID: 40579143 DOI: 10.12122/j.issn.1673-4254.2025.06.19
OBJECTIVES: To investigate the effect of ecliptasaponin A (ESA) for alleviating dextran sulfate sodium (DSS)-induced inflammatory bowel disease (IBD) in mice and the underlying mechanism. METHODS: Twenty-four male C57BL/6 mice (8-10 weeks old) were equally randomized into control group, DSS-induced IBD model group, and DSS+ESA (50 mg/kg) treatment group. Disease …
Caregiving Experiences of Caregivers of Adolescents With Inflammatory Bowel Disease: A Qualitative Meta-Synthesis
Publication Year: 2025 Source: Nurs Open PMID: 40579751 DOI: 10.1002/nop2.70267
BACKGROUND: Inflammatory Bowel Disease (IBD) is a chronic condition that significantly affects the physical and mental health of adolescents. Caregivers are crucial in the treatment process, offering both physical care and emotional support. Caring for adolescents with IBD can significantly affect caregivers' physical, psychological and daily lives, presenting a range …
Sexual and Reproductive Health for Women Who Live With Inflammatory Bowel Disease: An Integrative Review
Publication Year: 2025 Source: Nurs Open PMID: 40579754
AIMS: To provide an understanding of the sexual and reproductive health issues for women who live with inflammatory bowel disease. DESIGN: Whittemore and Knaffle's integrative review. METHODS: Databases searched in this integrative review included: CINAHL Plus, Google Scholar, SCOPUS and Web of Science databases. A defined research aim guided the …
Dual-Signal Electrochemical Aptasensor Based on High-Entropy Alloy Nanosheets for Calprotectin Detection in Inflammatory Bowel Disease
Publication Year: 2025 Source: ACS Appl Mater Interfaces PMID: 40580097 DOI: 10.1021/acsami.5c08094
The development of biofunctional electrochemical aptasensors represents an emerging frontier in diagnostic technology, yet achieving precise and ultrasensitive detection of inflammatory bowel disease (IBD) biomarkers for early stage diagnosis remains a critical challenge. To overcome this, we engineered a novel material-based electrochemical aptasensor by using amino acid-functionalized high-entropy alloy nanosheets …
Structural Characterization and Protective Effects of Camellia oleifera Fruit Shell Polysaccharides against DSS-Induced Ulcerative Colitis in Mice
Publication Year: 2025 Source: J Agric Food Chem PMID: 40580131
Plant polysaccharides have been reported to possess multiple pharmacological effects that can inhibit the progression of inflammatory diseases. The shell of Camellia oleifera fruits is a byproduct of the C. oleifera industry that is insufficiently utilized. Herein, a novel polysaccharide (CFP-A) was purified from C. oleifera fruit shells, and its …
Targeting the double-edged sword: cytokines in the pathogenesis and treatment of autoimmune diseases
Publication Year: 2025 Source: Inflammopharmacology PMID: 40580299 DOI: 10.1007/s10787-025-01817-8
Autoimmune diseases are often idiopathic, with complex immune cell interactions that remain poorly understood. Cytokines, signaling molecules with a dual nature, play a pivotal role in these conditions. While they are essential for regulating immune responses and have therapeutic applications, they can also contribute to inflammation and the development of …
Gene behaviors-based network enrichment analysis and its application to reveal immune disease pathways enriched with COVID-19 severity-specific gene networks
Publication Year: 2025 Source: Bioinformatics PMID: 40580453
MOTIVATION: Gene network analysis is essential for understanding the complex mechanisms underlying diseases, which often involve disruptions in molecular networks rather than individual genes. Despite the availability of large-scale omics datasets and computational tools for gene network analysis, interpretation of the biological relevance of these extensive networks remains challenging. RESULTS: …
IBDAIM:Artificial intelligence for analyzing intestinal biopsies pathological images for assisted integrated diagnostic of inflammatory bowel disease
Publication Year: 2025 Source: Int J Med Inform PMID: 40580688 DOI: 10.1016/j.ijmedinf.2025.106024
BACKGROUND: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is challenging to diagnose accurately from pathological images due to its complex histological features. This study aims to develop an artificial intelligence (AI) model, IBDAIM, to assist pathologists in quickly and accurately diagnosing IBD by analyzing whole-slide …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide