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Use of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Inflammatory Bowel Disease
Publication Year: 2025 Source: Gastroenterol Hepatol (N Y) PMID: 39897342
No Abstract
Mesalazine-Induced Acute Pancreatitis in Inflammatory Bowel Disease Patients: A Systematic Review
Publication Year: 2025 Source: Ther Clin Risk Manag PMID: 39897345 DOI: 10.2147/TCRM.S493371
OBJECTIVE: Mesalazine is a widely used medication for treating mild to moderate inflammatory bowel disease (IBD). First identified as a potential cause of acute pancreatitis (AP) in 1989, the link between mesalazine and AP has primarily been established through case reports and a limited number of retrospective studies. This study …
Serum salusin levels in diarrhea- and constipation-predominant irritable bowel syndrome
Publication Year: 2025 Source: PeerJ PMID: 39897500
OBJECTIVE: Inflammation and immunity play major roles in the etiopathogenesis of functional intestinal disorders. The salusins that were identified in this study are important because of their ease of collection, sensitivity and reliability. For that reason, the aim of this study was to analyze the importance of the levels of …
Intermittent Fasting Reduces Intestinal Inflammation in Dextran Sulfate Sodium-Induced Colitis of Mice
Publication Year: 2025 Source: Food Sci Nutr PMID: 39898122 DOI: 10.1002/fsn3.70014
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a chronic condition impacting both the gastrointestinal tract and the immune system. Intestinal inflammation and epithelial injury are the pathological features of IBD. Recent studies have reported that some strategies of dietary restriction (DR) can regulate immune …
Association between large vessel vasculitis and inflammatory bowel disease: a case-control study
Publication Year: 2025 Source: Rheumatology (Oxford) PMID: 39898825 DOI: 10.1093/rheumatology/keaf030
OBJECTIVES: To describe the characteristics and outcome of patients with the association of large vessel vasculitis (LVV, Takayasu arteritis [TA] or GCA) and IBD. METHODS: An observational, multicentre, retrospective case-control study. Cases were LVV-IBD patients from European countries, whereas controls had isolated LVV (iLVV). RESULTS: A total of 39 TA-IBD …
MR enterography in Crohns disease and beyond: a pictorial review : Beyond Crohn's: a pictorial guide to MR enterography in small bowel disease
Publication Year: 2025 Source: Abdom Radiol (NY) PMID: 39899083
Magnetic resonance enterography (MRE) has become an essential imaging modality for evaluating small bowel disorders, particularly Crohn's disease (CD), due to its superior soft-tissue contrast, multiplanar capabilities, and lack of ionizing radiation. While radiologists are generally familiar with the MRE findings of CD, several other small bowel entities can present …
The Consequences of Preterm Birth in the Children of Mothers with Inflammatory Bowel Disease: A Nationwide Cohort Study
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39899387 DOI: 10.1093/ibd/izaf010
INTRODUCTION: Mothers with inflammatory bowel disease (IBD) are at increased risk of delivering their infants preterm. In the general population, chronic diseases in adulthood as well as increased morbidity and mortality are associated with being born preterm. We aimed to examine whether this was true for preterm versus full-term infants …
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy
Publication Year: 2025 Source: PLoS Biol PMID: 39899477 DOI: 10.1371/journal.pbio.3002961
Inflammatory bowel disease (IBD) is a chronic and potentially life-threatening inflammatory disease of gastroenteric tissue characterized by episodes of intestinal inflammation, but the underlying mechanisms remain elusive. Here, we explore the role and precise mechanism of Van-Gogh-like 2 (VANGL2) during the pathogenesis of IBD. VANGL2 decreases in IBD patients and …
Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface
Publication Year: 2025 Source: Blood PMID: 39899882 DOI: 10.1182/blood.2024025240
The controlled development of cellular intestinal immunity in the face of dynamic microbiota emergence constitutes a major challenge in very early life and is a bottleneck for sustained growth and well-being. Early-onset inflammatory bowel disease (IBD) represents an extreme disturbance of intestinal immunity. It is a hallmark and often the …
Efficacy of Dose Escalation of Ustekinumab in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Publication Year: 2025 Source: Med Princ Pract PMID: 39900017 DOI: 10.1159/000543831
BACKGROUND: Ustekinumab is an effective drug in the treatment of inflammatory bowel disease (IBD), but inadequate response or loss of response is reported in several patients. Dose escalation by intravenous reinduction or interval shortening may be a suitable option to recapture response. We undertook a systematic review and meta-analysis to …
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