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Disulfidptosis and Its Hub Gene Slc3a2 Involved in Ulcerative Colitis Pathogenesis, Disease Progression, and Patient Responses to Biologic Therapies

Publication Year: 2024 Source: Int J Mol Sci PMID: 39769269

No Abstract

The Effect of Milk-Derived Extracellular Vesicles on Intestinal Epithelial Cell Proliferation

Publication Year: 2024 Source: Int J Mol Sci PMID: 39769282 DOI: 10.3390/ijms252413519

Inflammatory bowel disease (IBD) is a chronic, relapsing inflammation disorder of the gastrointestinal tract characterized by disrupted intestinal epithelial barrier function. Despite advances in treatment, including biological agents, achieving sustained remission remains challenging for many patients with IBD. This highlights the urgent need for novel therapeutic strategies. Milk-derived extracellular vesicles …

Mucosal Bacterial Immunotherapy Attenuates the Development of Experimental Colitis by Reducing Inflammation Through the Regulation of Myeloid Cells

Publication Year: 2024 Source: Int J Mol Sci PMID: 39769391

No Abstract

The Multifaceted Impact of Bioactive Lipids on Gut Health and Disease

Publication Year: 2024 Source: Int J Mol Sci PMID: 39769399 DOI: 10.3390/ijms252413638

Bioactive lipids have a multifaceted role in health and disease and are recognized to play an important part in gut immunity and disease conditions such as inflammatory bowel disease and colon cancer. Advancements in lipidomics, enabled by mass spectrometry and chromatographic techniques, have enhanced our understanding of lipid diversity and …

FISH-Flow Cytometry Reveals Microbiome-Wide Changes in Post-Translational Modification and Altered Microbial Abundance Among Children with Inflammatory Bowel Disease

Publication Year: 2024 Source: Pathogens PMID: 39770361 DOI: 10.3390/pathogens13121102

Metaproteomic analysis of microbiome post-translation modifications (PTMm) is challenging, and little is known about the effects of inflammation on the bacterial PTM landscape in IBD. Here, we adapted and optimised fluorescence in situ hybridisation-flow cytometry (FISH-FC) to study microbiome-wide tyrosine phosphorylation (p-Tyr) in children with and without inflammatory bowel disease …

Pathology and VP2-Based Characterization of Infectious Bursal Disease Virus Associated with an Outbreak in Layer Chickens in Ghana

Publication Year: 2024 Source: Pathogens PMID: 39770374 DOI: 10.3390/pathogens13121115

Infectious bursal disease (IBD) continues to threaten poultry production globally, with highly virulent strains circulating in many parts of Africa. In this study, molecular characterization was performed on a circulating infectious bursal disease virus (IBDV) strain from an outbreak in a layer flock in Ghana. Layer chicks presented for necropsy …

The Dynamic Role of Curcumin in Mitigating Human Illnesses: Recent Advances in Therapeutic Applications

Publication Year: 2024 Source: Pharmaceuticals (Basel) PMID: 39770516

No Abstract

Bacillus clausii Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice

Publication Year: 2024 Source: Pharmaceuticals (Basel) PMID: 39770518

No Abstract

Separating Infectious Proctitis from Inflammatory Bowel Disease-A Common Clinical Conundrum

Publication Year: 2024 Source: Microorganisms PMID: 39770599

No Abstract

Fecal Microbiota Transplantation for Chronic Pouchitis: A Systematic Review and Meta-Analysis

Publication Year: 2024 Source: Microorganisms PMID: 39770634 DOI: 10.3390/microorganisms12122430

Pouchitis is a common complication after ileal-pouch anal anastomosis in patients with medically refractory ulcerative colitis. There has been a lack of high-level evidence focusing on the safety and efficacy outcomes of fecal microbiota transplantation (FMT). We aim to evaluate outcomes and complications of fecal microbiota transplantation (FMT) for chronic …

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