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Oral administration of Sophora Flavescens-derived exosomes-like nanovesicles carrying CX5461 ameliorates DSS-induced colitis in mice
Publication Year: 2024 Source: J Nanobiotechnology PMID: 39379937
No Abstract
Enhancing radiologist's detection: an imaging-based grading system for differentiating Crohn's disease from ulcerative colitis
Publication Year: 2024 Source: BMC Med PMID: 39379964 DOI: 10.1186/s12916-024-03669-5
BACKGROUND: Delayed diagnosis of inflammatory bowel disease (IBD) is common, there is still no effective imaging system to distinguish Crohn's Disease (CD) and Ulcerative Colitis (UC) patients. METHODS: This multicenter retrospective study included IBD patients at three centers between January 2012 and May 2022. The intestinal and perianal imaging signs …
Regulatory effects of the p38 mitogen-activated protein kinase-myosin light chain kinase pathway on the intestinal epithelial mechanical barrier and the mechanism of modified Pulsatilla decoction in the treatment of ulcerative colitis
Publication Year: 2024 Source: J Tradit Chin Med PMID: 39380219
No Abstract
Huaiyu pill alleviates inflammatory bowel disease in mice blocking toll like receptor 4/ myeloid differentiation primary response gene 88/ nuclear factor kappa B subunit 1 pathway
Publication Year: 2024 Source: J Tradit Chin Med PMID: 39380222 DOI: 10.19852/j.cnki.jtcm.20240719.001
OBJECTIVE: To investigate the therapeutic effects of Huaiyu pill (, HYP) on inflammatory bowel disease (IBD) and the underlying mechanisms have not been elucidated. METHODS: To establish the IBD model, mice were administered with dextran sulfate sodium (DSS). Mice were intragastrically pre-treated with sulfasalazine (SASP) and HYP. Disease activity index …
Opportunistic infections changed before and after SARS-CoV-2 infection in inflammatory bowel disease patients: a retrospective single-center study in China
Publication Year: 2024 Source: Front Med (Lausanne) PMID: 39380736 DOI: 10.3389/fmed.2024.1461801
OBJECTIVE: SARS-CoV-2 transmission has become a serious worldwide public health concern. However, there is currently insufficient data to determine whether SARS-CoV-2 infection would affect opportunistic infections in inflammatory bowel disease (IBD) patients. METHODS: A retrospective study included 451 IBD patients (294 UC and 157 CD). The IBD patients were divided …
Fecal microbiota and metabolites in the pathogenesis and precision medicine for inflammatory bowel disease
Publication Year: 2024 Source: Precis Clin Med PMID: 39381014 DOI: 10.1093/pcmedi/pbae023
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract, and its pathogenesis is believed to be associated with an imbalance between commensal organisms and the intestinal immune system. This imbalance is significantly influenced by the intestinal microbiota and metabolites and plays a critical role in maintaining …
Intestinal flora and inflammatory bowel disease: Causal relationships and predictive models
Publication Year: 2024 Source: Heliyon PMID: 39381207 DOI: 10.1016/j.heliyon.2024.e38101
BACKGROUND: Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is significantly influenced by intestinal flora. Understanding the genetic and microbiotic interplay is crucial for IBD prediction and treatment. METHODS: We used Mendelian randomization (MR), transcriptomic analysis, and machine learning techniques, integrating data from the MiBioGen Consortium and various …
The Potential Benefits of Exercise in Managing Inflammatory Bowel Disease: A Systematic Review
Publication Year: 2024 Source: Cureus PMID: 39381484 DOI: 10.7759/cureus.68948
Adults with inflammatory bowel disease (IBD) experience a significant decline in quality of life due to various symptoms. Exercise has emerged as a potential therapeutic approach to improve IBD management, but its effectiveness requires further investigation. This systematic review, adhering to PRISMA 2020 guidelines, explored the effects of exercise on …
Hospital admissions for pyoderma gangrenosum in Spain (1999-2021): Epidemiological and clinical characteristics, temporal trends, and factors associated with poor prognosis and higher cost
Publication Year: 2024 Source: Health Sci Rep PMID: 39381532
No Abstract
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing
Publication Year: 2024 Source: Allergol Select PMID: 39381601
No Abstract
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