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Anti-Interleukin-23 Treatment Linked to Improved Clostridioides difficile Infection Survival
Publication Year: 2024 Source: medRxiv PMID: 39677433
No Abstract
Cystic fibrosis risk variants confer protection against inflammatory bowel disease
Publication Year: 2024 Source: medRxiv PMID: 39677473 DOI: 10.1101/2024.12.02.24318364
Genetic mutations that yield defective cystic fibrosis transmembrane regulator (CFTR) protein cause cystic fibrosis, a life-limiting autosomal recessive Mendelian disorder. A protective role of CFTR loss-of-function mutations in inflammatory bowel disease (IBD) has been suggested, but its evidence has been inconclusive and contradictory. Here, leveraging the largest IBD exome sequencing …
Shared Genetics of Migraine and Gastrointestinal Disorders Implicates Underlying Neurologic Mechanisms Yet Heterogeneous Etiologies
Publication Year: 2024 Source: Neurol Genet PMID: 39677849 DOI: 10.1212/NXG.0000000000200201
BACKGROUND AND OBJECTIVES: Migraine is strongly comorbid with irritable bowel syndrome (IBS), one of several gastrointestinal (GI) conditions that are distinguished by symptomatic profiles that are partly overlapping. Potential shared mechanisms of migraine and the GI conditions were investigated by assessing shared genetics on a genome-wide basis. METHODS: Analyses leveraged …
The Association Between Atopic Dermatitis and Inflammatory Bowel Disease Risk: A Meta-Analysis of Longitudinal Studies
Publication Year: 2024 Source: JGH Open PMID: 39678631 DOI: 10.1002/jgh3.70077
AIMS: This review aimed to investigate whether atopic dermatitis (AD) increases the risk of inflammatory bowel disease (IBD) by analyzing data from longitudinal studies. METHODS: Cohort and case-control studies evaluating the association between AD and the risk of IBD, Crohn's disease (CD), or ulcerative colitis (UC) were included. Literature searches …
Clinical Characteristics and Treatment of Middle-Aged and Elderly Patients with IBD in Shanghai, China
Publication Year: 2024 Source: Int J Gen Med PMID: 39678677 DOI: 10.2147/IJGM.S485079
AIM: In order to better understand the incidence of IBD in China, we conducted a retrospective study to analyze the clinical information of IBD patients in Shanghai, China. METHODS: From January 2014 to December 2021, patients diagnosed with IBD and hospitalized were enrolled. The demographic, clinical features, symptoms, laboratory tests …
Ex Vivo Evaluation of a Soft Optical Blood Sensor for Colonoscopy
Publication Year: 2024 Source: Device PMID: 39678941
No Abstract
Response from the Canadian Children Inflammatory Bowel Disease Network to the US Food and Drug Administration Draft Guidance for Industry on pediatric inflammatory bowel disease: developing drugs for treatment
Publication Year: 2024 Source: J Can Assoc Gastroenterol PMID: 39679099 DOI: 10.1093/jcag/gwae034
No Abstract
Acceptability, feasibility, and impact of the MyGut digital health platform in the monitoring and management of inflammatory bowel disease
Publication Year: 2024 Source: J Can Assoc Gastroenterol PMID: 39679104 DOI: 10.1093/jcag/gwae029
BACKGROUND: Digital health monitoring may help facilitate self-management strategies when caring for patients with inflammatory bowel disease (IBD). AIMS: This study investigated the feasibility of implementing the MyGut health application when caring for patients with IBD and evaluated whether its use improved health outcomes. METHODS: We conducted a prospective trial …
Portulaca Oleracea L. as a Potential Therapeutic Drug Intervention in Ulcerative Colitis: Mechanisms of Action and Clinical Studies
Publication Year: 2024 Source: Drug Des Devel Ther PMID: 39679131 DOI: 10.2147/DDDT.S486407
Portulaca oleracea L. (POL) has a long history of medicinal use worldwide, and numerous clinical and experimental studies demonstrated the therapeutic effects of POL and its active ingredients in the treatment of Ulcerative colitis (UC). In this review, we summarized the underlying mechanisms and roles of POL in UC treatment …
Clinical Course of Isolated Recurrent, Persistent Complex Perianal Fistulas Without Luminal Crohn's Disease: A Multicenter Case Series of 24 Patients
Publication Year: 2024 Source: Crohns Colitis 360 PMID: 39679162
No Abstract
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