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Predictive Model for Outcomes in Inflammatory Bowel Disease Patients Receiving Maintenance Infliximab Therapy
Publication Year: 2024 Source: Crohns Colitis 360 PMID: 39679163 DOI: 10.1093/crocol/otae052
BACKGROUND: No models predict future outcomes in inflammatory bowel disease (IBD) patients receiving maintenance infliximab therapy. We created a predictive model for unfavorable outcomes. METHODS: Adult patients with IBD receiving maintenance infliximab therapy at 2 centers with matched serum infliximab concentrations and blinded histologic scores (Robarts Histopathologic Index [RHI]) were …
Oral Targeted Delivery of Codonopsis Radix Polysaccharide via Succinyl -DHA Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
Publication Year: 2024 Source: Int J Nanomedicine PMID: 39679251
No Abstract
Lipocalin-2 and intestinal diseases
Publication Year: 2024 Source: World J Gastroenterol PMID: 39679305
No Abstract
Gut microbiota and mesenteric adipose tissue interactions in shaping phenotypes and treatment strategies for Crohn's disease
Publication Year: 2024 Source: World J Gastroenterol PMID: 39679306
No Abstract
Real-world experience and long-term outcomes of a mandatory non-medical switch of adalimumab originator to biosimilars in inflammatory bowel disease
Publication Year: 2024 Source: World J Gastroenterol PMID: 39679312 DOI: 10.3748/wjg.v30.i46.4904
BACKGROUND: Over the last decade, the treatment options for inflammatory bowel disease (IBD) have significantly progressed with the emergence of new medications designed to target various immune pathways and mitigate inflammation. Adalimumab (ADA) is a tumor necrosis factor alpha antagonist and stands as an effective treatment for IBD. In April …
Nanomedicine: The new trend and future of precision medicine for inflammatory bowel disease
Publication Year: 2024 Source: Chin Med J (Engl) PMID: 39679456
No Abstract
Combined Bulk and Single-Cell Transcriptomic Analysis to Reveal the Potential Influences of Intestinal Inflammatory Disease on Multiple Sclerosis
Publication Year: 2024 Source: Inflammation PMID: 39680254 DOI: 10.1007/s10753-024-02195-z
Multiple sclerosis (MS) and inflammatory bowel disease (IBD) are both autoimmune disorders caused by dysregulated immune responses. Still, there is a growing awareness of the comorbidity between MS and IBD. However, the shared pathophysiological mechanisms between these two diseases are still lacking. RNA sequencing datasets (GSE126124, GSE9686, GSE36807, GSE21942) were …
Diagnosing endometriosis: Endometriosis: diagnosis and management: Evidence review B
Publication Year: 2024 Source: Diagnosing endometriosis: Endometriosis: diagnosis and management: Evidence review B PMID: 39680692
No Abstract
Cyanobacteria-probiotics symbionts for modulation of intestinal inflammation and microbiome dysregulation in colitis
Publication Year: 2024 Source: Proc Natl Acad Sci U S A PMID: 39680761 DOI: 10.1073/pnas.2403417121
Inflammatory bowel disease (IBD) is often associated with excessive inflammatory response and highly dysregulated gut microbiota. Traditional treatments utilize drugs to manage inflammation, potentially with probiotic therapy as an adjuvant. However, current standard practices often suffer from detrimental side effects, low bioavailability, and unsatisfactory therapeutic outcomes. Microbial complexes characterized by …
Mucin Promotes Bacterial Swarming by Making the Agar Surface More Slippery
Publication Year: 2024 Source: Langmuir PMID: 39680870 DOI: 10.1021/acs.langmuir.4c03395
When inoculated on the surface of soft agar containing nutrients, many species of motile bacteria can grow into a dense population and spread across the surface by a form of motility called swarming. We study the swarming behavior of Enterobacter sp. SM3, a species of bacteria that exhibits a swarm-dependent …
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