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Addressing Inflammaging and Disease-Related Malnutrition: Adequacy of Oral Nutritional Supplements in Clinical Care
Publication Year: 2024 Source: Nutrients PMID: 39683535
No Abstract
Nutritional Management in Stricturing Crohn's Disease: A Pilot Study
Publication Year: 2024 Source: Nutrients PMID: 39683547 DOI: 10.3390/nu16234153
BACKGROUND: More than half of patients with Crohn's disease develop intestinal fibrosis induced intestinal obstruction with debilitating symptoms throughout their disease course. The incidence of stricture formation in CD has remained unchanged over the last several decades. Factors promoting intestinal fibrosis are currently unclear, but diet may represent an underestimated …
Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative Colitis: A Randomized Controlled Trial
Publication Year: 2024 Source: Nutrients PMID: 39683589 DOI: 10.3390/nu16234197
Background: Bilberries are effective in inducing clinical, endoscopic, and biochemical improvement in ulcerative colitis (UC) patients. The aim of this study was to investigate the efficacy of anthocyanin-rich extract (ACRE), the bioactive ingredient of bilberries, in a controlled clinical trial in moderate-to-severe UC. Methods: A multi-center, randomized, placebo-controlled, double-blind study …
The Key Nutrients in the Mediterranean Diet and Their Effects in Inflammatory Bowel Disease: A Narrative Review
Publication Year: 2024 Source: Nutrients PMID: 39683595 DOI: 10.3390/nu16234201
The gut microbiome, a collection of gut microorganisms, is crucial in the development and progression of inflammatory bowel diseases (IBD). Therefore, diet and dietary interventions are promising strategies to shape the gut microbiota for IBD management. Of all the diets studied in the IBD field, the Mediterranean diet has the …
Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection
Publication Year: 2024 Source: Int J Mol Sci PMID: 39684365 DOI: 10.3390/ijms252312653
Clostridioides difficile (C. difficile) is a global threat and has significant implications for individuals and health care systems. Little is known about host molecular mechanisms and transcriptional changes in peripheral immune cells. This is the first gene expression study in whole blood from patients with C. difficile infection. We took …
Anorectal Remodeling in the Transitional Zone with Increased Expression of LGR5, SOX9, SOX2, and Keratin 13 and 5 in a Dextran Sodium Sulfate-Induced Mouse Model of Ulcerative Colitis
Publication Year: 2024 Source: Int J Mol Sci PMID: 39684417
No Abstract
Drosophila: An Important Model for Exploring the Pathways of Inflammatory Bowel Disease (IBD) in the Intestinal Tract
Publication Year: 2024 Source: Int J Mol Sci PMID: 39684456 DOI: 10.3390/ijms252312742
Inflammatory bowel disease (IBD) is a chronic and recurring lifelong condition, the exact etiology of which remains obscure. However, an increasing corpus of research underscores the pivotal role of cellular signaling pathways in both the instigation and management of intestinal inflammation. Drosophila, owing to its prodigious offspring, abbreviated life cycle, …
Pancreastatin Inhibition Alters the Colonic Epithelial Cells Profile in a Sex-Dependent Manner
Publication Year: 2024 Source: Int J Mol Sci PMID: 39684467
No Abstract
Understanding Quorum-Sensing and Biofilm Forming in Anaerobic Bacterial Communities
Publication Year: 2024 Source: Int J Mol Sci PMID: 39684519
No Abstract
Association of Gut Microbiome and Dipeptidyl Peptidase 4 in Immune-Mediated Inflammatory Bowel Disease: A Rapid Literature Review
Publication Year: 2024 Source: Int J Mol Sci PMID: 39684563 DOI: 10.3390/ijms252312852
Immune-mediated inflammatory diseases (IMIDs) are characterized by dysregulated immune responses and chronic tissue inflammation. In the setting of inflammatory bowel disease (IBD), dipeptidyl peptidase 4 (DPP4) and gut microorganisms have been proved to interplay, potentially influenced by dietary factors. This rapid review aimed to study the DPP4-gut microbiome link in …
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