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Medication-related burden among Iraqi patients with ulcerative colitis: a cross-sectional study

Publication Year: 2024 Source: J Med Life PMID: 39539436 DOI: 10.25122/jml-2023-0342

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by recurring periods of inflammation and remission, primarily affecting the colon. The concept of medication-related burden, which refers to the adverse effects experienced by patients due to conventional medical treatments, is relatively new in the field. This study aimed to …

Appropriateness of small molecule agents for patients with IBD of childbearing age - a RAND/UCLA appropriateness panel

Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 39539488 DOI: 10.1177/17562848241299737

BACKGROUND: Many women of childbearing age with inflammatory bowel disease (IBD) require advanced therapies. While biologics are largely low risk during pregnancy, the novel small molecules tofacitinib, filgotinib, upadacitinib and ozanimod (TFUO) have shown concerning teratogenic effects, and decreased fertility in animal studies. Therefore, their use in women of childbearing …

Aphthous lesions turned out to be neonatal very early-onset inflammatory bowel disease: a case report

Publication Year: 2024 Source: Front Pediatr PMID: 39539768 DOI: 10.3389/fped.2024.1433852

Neonatal diagnosis of inflammatory bowel disease (IBD) proves challenging due to its non-specific symptoms. A term-born neonate showing states of inflammation and aphthae was treated for sepsis and candidiasis before being diagnosed with interleukin-10 receptor deficiency and consecutive IBD. The patient was finally successfully treated by stem cell transplantation. The …

The Risk of Venous Thromboembolism in Children With Inflammatory Bowel Disease

Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 39540429 DOI: 10.1093/ibd/izae249

BACKGROUND: Recent studies of children with inflammatory bowel disease (IBD) demonstrate an increased venous thromboembolism (VTE) risk. However, estimates of risk are variable and case numbers are limited. The aim of this study was to provide national estimates of the risk of VTE in children with IBD. METHODS: Hospital Episode …

Familial Mediterranean Fever in Childhood

Publication Year: 2024 Source: Turk Arch Pediatr PMID: 39540697

No Abstract

Heterogeneity of definition of upper gastrointestinal tract in different guidelines of Crohn's disease: A scoping review

Publication Year: 2024 Source: United European Gastroenterol J PMID: 39541219 DOI: 10.1002/ueg2.12697

Crohn's Disease (CD) can affect any part of the gastrointestinal (GI) tract, including the upper GI tract (UGIT). However, the definitions and classifications of upper GI CD (UGICD) vary. We conducted a scoping review to explore how UGIT and UGICD are defined and to assess the heterogeneity of these definitions …

Methods for corticosteroid withdrawal: Adrenal insufficiency: identification and management: Evidence review E

Publication Year: 2024 Source: Methods for corticosteroid withdrawal: Adrenal insufficiency: identification and management: Evidence review E PMID: 39541482

No Abstract

When to refer for specialist investigation when withdrawing corticosteroids: Adrenal insufficiency: identification and management: Evidence review C

Publication Year: 2024 Source: When to refer for specialist investigation when withdrawing corticosteroids: Adrenal insufficiency: identification and management: Evidence review C PMID: 39541483

No Abstract

Microbiota-induced alteration of kynurenine metabolism in macrophages drives formation of creeping fat in Crohn's disease

Publication Year: 2024 Source: Cell Host Microbe PMID: 39541945

No Abstract

Impact of musculoskeletal joint complaints on quality of life in patients with inflammatory bowel disease: a cross-sectional study

Publication Year: 2024 Source: BMJ Open PMID: 39542476 DOI: 10.1136/bmjopen-2024-088350

BACKGROUND: Musculoskeletal joint complaints (MSCs) are the most common extraintestinal manifestation of inflammatory bowel disease (IBD). We aimed to investigate the effect of MSC on the health-related quality of life (QoL) in patients with IBD. DESIGN: A survey-based cross-sectional study among adult Dutch IBD patients. SETTING: Primary care, secondary care …

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