Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Association of PTPN22 single nucleotide polymorphisms (-1123G/C, +788G/A and +1858C/T) with inflammatory bowel disease
Publication Year: 2025 Source: Egypt J Immunol PMID: 40684363
Inflammatory bowel disease (IBD) is a class of chronic inflammatory disorders including, Crohn's disease (CD) and ulcerative colitis (UC). The PTPN22 gene is thought to be a T-cell negative regulator, regulates immune cell activation, and an important risk factor for human autoimmunity. This study aimed to investigate the potential association …
Serum miRNA 146b-5p a pharmacodynamic biomarker in adult inflammatory bowel disease
Publication Year: 2025 Source: Egypt J Immunol PMID: 40684351
Inflammatory bowel disease (IBD) impacts the gastrointestinal tract, resulting in multiple hospitalizations, complications, and diminished quality of life. IBD has two subtypes: Crohn's Disease (CD) and Ulcerative Colitis (UC). Evidence suggested that immune response dysregulation and genetic susceptibility are the main disease pathogenesis. IBD diagnosis is established by clinical, laboratory, …
Long-term impact of computer-aided adenoma detection: a prospective observational study
Publication Year: 2025 Source: Endoscopy PMID: 40683257
BACKGROUND AND AIMS: Computer-aided detection (CADe) systems have improved the adenoma detection rate (ADR). However, concerns about its long-term effect on endoscopists' performance without CADe and potential deskilling remain unknown. This study evaluated the impact of CADe on the learning curve of endoscopists for ADR. METHODS: This propensity score matching, …
Collagen-Anchoring Polymer Dots Enable Rapid and Precise Detection of Microlesions in Inflammatory Bowel Disease through Perivascular Matrix Accumulation
Publication Year: 2025 Source: Adv Healthc Mater PMID: 40685960
Inflammatory bowel disease (IBD) poses substantial challenges in early diagnosis and the detection of small lesions due to clinical heterogeneity and limitations of existing imaging techniques. In this study, functional polymer dots (Pdots) are developed to rapidly and precisely image microlesions by extravasating from IBD-associated vasculature and anchoring within the …
Efficacy of tirzepatide for weight loss and it's comparative effectiveness to weight loss surgery in inflammatory bowel disease
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 40682732
BACKGROUND AND AIMS: There is limited data about tirzepatide's (TZP) efficacy for weight loss in patients with inflammatory bowel disease (IBD). METHODS: A retrospective cohort study was conducted using the US Collaborative Network in patients with IBD on TZP between January 5, 2022 and December 31, 2023. The objective was …
Magnetic resonance imaging to differentiate between Crohn's disease-associated and cryptoglandular perianal fistula
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 40682731
BACKGROUND: The radiological features of Crohn's disease (CD)-associated and cryptoglandular perianal fistulae (PAF) are similar, but distinguishing them is crucial for treatment decisions. Delayed CD diagnosis in PAF can worsen long-term outcomes and accurate radiological differentiation may help identify CD-associated PAF. METHODS: In a retrospective single-center study, we analyzed the …
Clinical utility of thiopurine metabolite levels in monitoring patients with inflammatory bowel disease: A single-centre retrospective study
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 40682730
BACKGROUND: Therapeutic drug monitoring (TDM) of thiopurines is crucial for optimizing inflammatory bowel disease (IBD) treatment. Despite its benefits, data on thiopurine levels in Indian IBD patients is limited. Thus, we assessed 6-thioguanine nucleotide (6-TGN) and 6-methyl mercaptopurine (6-MMP) levels in patients on thiopurine therapy and evaluated their correlation with …
Economic burden borne by patients due to diagnostic delays in inflammatory bowel disease: Insights from a survey of newly diagnosed patients
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 40682729
BACKGROUND AND OBJECTIVE: Patients with inflammatory bowel disease (IBD) often experience diagnostic delays owing to the absence of a definitive test. In our country, it is compounded by difficulty in differentiating it from tuberculosis, in certain situations. Hence, we decided to specifically estimate the economic burden that patients with IBD …
Critique on "Risk profile of promoters and inhibitors of kidney stone formation in paediatric inflammatory bowel disease"
Publication Year: 2025 Source: Pediatr Nephrol PMID: 40682659
No Abstract
Mucosal Responses to Type II Interferon in IBD
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 40682561
No Abstract
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide