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Histopathological outcome predictors of quiescence/remission in inflammatory bowel diseases: A need being addressed

Publication Year: 2024 Source: United European Gastroenterol J PMID: 39446653

No Abstract

Safety and Potential Efficacy of Expanded Umbilical Cord-Derived Mesenchymal Stromal Cells in Luminal Ulcerative Colitis Patients

Publication Year: 2024 Source: Stem Cells Dev PMID: 39446772 DOI: 10.1089/scd.2024.0102

Inflammatory bowel disease (IBD) is characterized by periods of flare-ups and remission. It is likely to be an autoimmune in origin, presenting persistent therapeutic challenges despite current therapies. This study aims to investigate the potential of umbilical cord mesenchymal stromal cells (UCMSCs) in treating ulcerative colitis (UC). This study is …

Agenda-setting in the clinical encounter: A systematic review protocol

Publication Year: 2024 Source: PLoS One PMID: 39446854

No Abstract

International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement

Publication Year: 2024 Source: Lancet Gastroenterol Hepatol PMID: 39447590

No Abstract

Real-world effectiveness and safety of CT-P13, an infliximab biosimilar, for inflammatory bowel diseases: A prospective national observational cohort study (ReFLECT study)

Publication Year: 2024 Source: Clin Res Hepatol Gastroenterol PMID: 39448029 DOI: 10.1016/j.clinre.2024.102483

BACKGROUND: ReFLECT was a French, prospective, multicenter, observational cohort study evaluating the effectiveness and safety of the infliximab (IFX) biosimilar CT-P13 in a real-world setting. Here, we describe the results for adults with inflammatory bowel disease (IBD). METHODS: Eligible patients with IBD were recruited and received intravenous CT-P13 induction and/or …

Identification of spontaneous patient-reported complaints related to perianal fistula in patients with Crohn's disease

Publication Year: 2024 Source: Colorectal Dis PMID: 39448386

No Abstract

Association of oral manifestations with severity of the disease in ulcerative colitis patients

Publication Year: 2024 Source: BMC Gastroenterol PMID: 39448908 DOI: 10.1186/s12876-024-03472-9

OBJECTIVE: Inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC), are chronic conditions primarily affecting the intestines. This study aims to identify the nature and frequency of oral symptoms and signs in patients with ulcerative colitis and to explore the connection between these complications and the …

Risk of Clostridioides difficile infection in inflammatory bowel disease patients undergoing vedolizumab treatment: a systematic review and meta-analysis

Publication Year: 2024 Source: BMC Gastroenterol PMID: 39448963 DOI: 10.1186/s12876-024-03460-z

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic, relapsing condition wherein biologics have improved disease prognosis but introduced elevated infection susceptibility. Vedolizumab (VDZ) demonstrates unique safety advantages; however, a comprehensive systematic comparison regarding the risk of Clostridioides difficile infection (CDI) between vedolizumab and alternative medications remains absent. METHOD: Medline, Embase, …

Berberine-loaded PLGA nanoparticles alleviate ulcerative colitis by targeting IL-6/IL-6R axis

Publication Year: 2024 Source: J Transl Med PMID: 39448992

No Abstract

Metabolic and lifestyle factors accelerate disease onset and alter gut microbiome in inflammatory non-communicable diseases

Publication Year: 2024 Source: BMC Med PMID: 39449123 DOI: 10.1186/s12916-024-03709-0

BACKGROUND: Biomedical and lifestyle factors in Western populations have significantly shifted in recent decades, influencing public health and contributing to the increasing prevalence of non-communicable diseases (NCDs) that share inflammation as common pathology. METHODS: We investigated the relationship between these factors and 11 NCDs in the cross-sectional FoCus cohort (n …

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