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Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis
Publication Year: 2024 Source: Nat Commun PMID: 38531883
No Abstract
Lacidophilin tablets alleviate constipation through regulation of intestinal microflora by promoting the colonization of Akkermansia sps
Publication Year: 2024 Source: Sci Rep PMID: 38531966
No Abstract
A Gastroenterologist's guide to drug interactions of small molecules for inflammatory bowel disease
Publication Year: 2024 Source: United European Gastroenterol J PMID: 38532266 DOI: 10.1002/ueg2.12559
Small molecule drugs are becoming increasingly used in the treatment of inflammatory bowel diseases (IBD). However, unlike monoclonal antibody drugs, which have few interactions with other medications, the pharmacokinetics of small molecule drugs are complex and may be influenced by a myriad of drug-drug interactions (DDI) as well as by …
Clinical statistical analysis plan for the ACCURE trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicentre trial
Publication Year: 2024 Source: Trials PMID: 38532488
No Abstract
Proton pump inhibitors enhance macropinocytosis-mediated extracellular vesicle endocytosis by inducing membrane v-ATPase assembly
Publication Year: 2024 Source: J Extracell Vesicles PMID: 38532609
No Abstract
Transplant of microbiota from Crohn's disease patients to germ-free mice results in colitis
Publication Year: 2024 Source: Gut Microbes PMID: 38532703 DOI: 10.1080/19490976.2024.2333483
Although the role of the intestinal microbiota in the pathogenesis of inflammatory bowel disease (IBD) is beyond debate, attempts to verify the causative role of IBD-associated dysbiosis have been limited to reports of promoting the disease in genetically susceptible mice or in chemically induced colitis. We aimed to further test …
Inter-brain desynchronization in social interaction: a consequence of subjective involvement?
Publication Year: 2024 Source: Front Hum Neurosci PMID: 38532790 DOI: 10.3389/fnhum.2024.1359841
Hyperscanning approaches to human neuroscience aim to uncover the neural mechanisms of social interaction. They have been largely guided by the expectation that increased levels of engagement between two persons will be supported by higher levels of inter-brain synchrony (IBS). A common approach to measuring IBS is phase synchrony in …
pH-responsive interface conversion efficient oral drug delivery platform for alleviating inflammatory bowel disease
Publication Year: 2024 Source: Front Chem PMID: 38532806 DOI: 10.3389/fchem.2024.1365880
A key challenge for the effective treatment of intestinal diseases, including inflammatory bowel disease (IBD), is to develop an oral drug delivery system that can resist gastric acid erosion and efficiently release drugs after rapid entry into the intestine. In the present work, we developed oral composite nanoparticles (MSZ@PRHS) consisting …
Efficacy of Pistacia lentiscus Plant (Rumi Mastagi) in Comparison to Levosulpiride in Patients with Diabetic Gastroparesis: A Double-Blind Non-Inferior Randomised Control Trial Study
Publication Year: 2024 Source: Indian J Endocrinol Metab PMID: 38533281 DOI: 10.4103/ijem.ijem_84_23
INTRODUCTION: Gastrointestinal neuropathies are frequently found in diabetic patients. The pathogenesis of diabetic gastroparesis (DG) is multifactorial. The usual treatment for DG includes dietary modifications, prokinetic and antiemetic agents. There is increasing demand for more effective medicines to treat DG. The current study was conducted on the Pistacia lentiscus stem …
C-reactive protein-to-albumin ratio and neutrophil-to-albumin ratio for predicting response and prognosis to infliximab in ulcerative colitis
Publication Year: 2024 Source: Front Med (Lausanne) PMID: 38533316
No Abstract
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