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Severe multiple therapy refractory colitis in a 46-year-old man

Publication Year: 2024 Source: Gut PMID: 38316541

No Abstract

Normal Infant Immunologic Assessment and Uneventful Live Rotavirus Vaccination Despite Continuous Tofacitinib Exposure In Utero and During Breastfeeding

Publication Year: 2024 Source: Crohns Colitis 360 PMID: 38317692 DOI: 10.1093/crocol/otae006

BACKGROUND: Janus kinase (JAK) inhibitors are effective for the treatment of inflammatory bowel disease (IBD). However, this class of medications is not recommended during pregnancy or breastfeeding based on animal data suggesting teratogenesis and recent reports of transmammary transfer after maternal ingestion, raising concerns for immune system development in babies …

Longitudinal monitoring of IL-6 and CRP in inflammatory bowel disease using IBD-AWARE

Publication Year: 2024 Source: Biosens Bioelectron X PMID: 38317723 DOI: 10.1016/j.biosx.2023.100435

There are limitations to monitoring modalities for chronic inflammatory conditions, including inflammatory bowel disease (IBD). Wearable devices are scalable mobile health technology that present an opportunity to monitor markers that have been linked to worsening, chronic inflammatory conditions and enable remote monitoring. In this research article, we evaluate and demonstrate …

Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease

Publication Year: 2024 Source: Bioact Mater PMID: 38318229 DOI: 10.1016/j.bioactmat.2024.01.016

Reactive oxygen species (ROS), immune dysregulation-induced inflammatory outbreaks and microbial imbalance play critical roles in the development of inflammatory bowel disease (IBD). Herein, a novel enzyme-like biomimetic oral-agent ZnPBA@YCW has been developed, using yeast cell wall (YCW) as the outer shell and zinc-doped Prussian blue analogue (ZnPBA) nanozyme inside. When …

Plants with Anti-Ulcer Activity and Mechanism: A Review of Preclinical and Clinical Studies

Publication Year: 2024 Source: Drug Des Devel Ther PMID: 38318501

No Abstract

Home-based fecal calprotectin utilization in a general pediatric gastroenterology clinic

Publication Year: 2024 Source: J Pediatr Gastroenterol Nutr PMID: 38318970 DOI: 10.1002/jpn3.12150

OBJECTIVE: Remote investigation and monitoring have gained importance in ambulatory practice. A home-based fecal calprotectin (FC) test has been developed where the sample is processed and analyzed at home through a smartphone application. We aimed to assess the use of standard ELISA (sFC) versus home-based (hFC) FC testing in a …

Patients With Inflammatory Bowel Disease Are at Increased Risk of Hospitalization Due to Respiratory Syncytial Virus

Publication Year: 2024 Source: Am J Gastroenterol PMID: 38318981 DOI: 10.14309/ajg.0000000000002682

INTRODUCTION: Patients with inflammatory bowel disease (IBD) are at increased risk of developing respiratory infections. Respiratory syncytial virus (RSV) is a common respiratory virus with adverse outcomes in older adults. This study aimed to determine whether patients with IBD are at increased risk of a serious infection due to RSV. …

Association between inflammatory bowel disease and frailty: a two-sample Mendelian randomization study

Publication Year: 2024 Source: Aging Clin Exp Res PMID: 38319411 DOI: 10.1007/s40520-023-02688-1

BACKGROUND: An association has been identified between inflammatory bowel disease (IBD) and frailty; however, the causal nature of this connection remains uncertain. We consequently conducted a two-sample Mendelian randomization (MR) analysis to explore this particular association. METHODS: We acquired distinct datasets for inflammatory bowel disease (IBD), Crohn's disease (CD), ulcerative …

Innate Immunity Activation in Newly Diagnosed Ileocolonic Crohn's Disease: A Cohort Study

Publication Year: 2024 Source: Dis Colon Rectum PMID: 38319717

No Abstract

Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis

Publication Year: 2024 Source: Aging (Albany NY) PMID: 38319729

No Abstract

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