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Upadacitinib Achieves Clinical and Endoscopic Outcomes in Crohn's Disease Regardless of Prior Biologic Exposure

Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 38492904

No Abstract

Predictive biomarkers for anti-TNF alpha therapy in IBD patients

Publication Year: 2024 Source: J Transl Med PMID: 38493113 DOI: 10.1186/s12967-024-05058-1

Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition characterized by severe gut inflammation, commonly presenting as Crohn's disease, ulcerative colitis or categorized as IBD- unclassified. While various treatments have demonstrated efficacy in adult IBD patients, the advent of anti-TNF therapies has significantly revolutionized treatment outcomes and clinical management. These …

Effect of Suboptimal Disease Control on Patient Quality of Life: Real-World Data from the Observational IBD-PODCAST Canada Trial

Publication Year: 2024 Source: Dig Dis Sci PMID: 38493273 DOI: 10.1007/s10620-024-08313-z

BACKGROUND: The real-world application of STRIDE-II treatment targets to identify whether disease control is optimal in Crohn's disease (CD) and ulcerative colitis (UC) is not well known. AIMS: This study aimed to estimate proportions of patients with suboptimally controlled CD and UC in real-world Canadian healthcare settings and the impact …

Low-Dose Aspirin Use Does Not Increase Disease Activity in Pregnant Patients with Inflammatory Bowel Disease

Publication Year: 2024 Source: Dig Dis Sci PMID: 38493274 DOI: 10.1007/s10620-024-08364-2

BACKGROUND: The adverse effects of non-steroidal anti-inflammatory (NSAID) drugs on the gastrointestinal system are well recognized, but the effect of NSAID use on disease activity patients with inflammatory bowel disease (IBD) remains unresolved. Low-dose aspirin (LDA) is recommended for all pregnant patients with risk factors for developing preeclampsia, including autoimmune …

Prognosis of Patients with Crohn's Disease and Ulcerative Colitis Following Percutaneous Coronary Intervention Procedures

Publication Year: 2024 Source: Isr Med Assoc J PMID: 38493327

BACKGROUND: Patients with inflammatory bowel disease (IBD) are at increased risk after percutaneous coronary intervention (PCI). OBJECTIVES: To compare the clinical outcomes within 30 days, one year, and five years of undergoing PCI. METHODS: We conducted a retrospective cohort study of adult patients with IBD who underwent PCI in a …

Takotsubo Syndrome and Colitis Due to Clostridium difficile: Is There a Relationship?

Publication Year: 2024 Source: Isr Med Assoc J PMID: 38493333

No Abstract

Single measurement of bowel wall thickness using intestinal ultrasonography in children with ulcerative colitis

Publication Year: 2024 Source: Pediatr Int PMID: 38493448

No Abstract

Sophoricoside improved Crohn's disease-like colitis by inhibiting intestinal epithelial cell apoptosis through PI3K/AKT signaling

Publication Year: 2024 Source: Int Immunopharmacol PMID: 38493691

No Abstract

Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity

Publication Year: 2024 Source: Cell Mol Gastroenterol Hepatol PMID: 38494056

No Abstract

Use of dual biologic therapy targeting the Th2 and Th17 axes simultaneously to treat patients with atopic dermatitis and concomitant psoriasis, psoriatic arthritis, or inflammatory bowel disease

Publication Year: 2024 Source: J Am Acad Dermatol PMID: 38494153

No Abstract

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