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The role of COX-2 and its use as a therapeutic target in IBD and related colorectal cancer
Publication Year: 2025 Source: Arch Biochem Biophys PMID: 40550348 DOI: 10.1016/j.abb.2025.110516
Inflammatory bowel disease (IBD) is a persistent inflammation of the gastrointestinal tract with a significant risk of progression to colorectal cancer (CRC). IBD and CRC have increased cyclooxygenase-2 (COX-2) levels, which is important in these conditions. In IBD, COX-2 contributes to intestinal inflammation, mucosal injury, and immune response dysregulation, while …
Risk of tuberculosis disease among patients with inflammatory bowel disease and inflammatory rheumatic disease treated with biologics in Denmark: a nationwide cohort study
Publication Year: 2025 Source: Clin Microbiol Infect PMID: 40550359 DOI: 10.1016/j.cmi.2025.06.017
OBJECTIVES: This nationwide retrospective cohort study estimates TB disease risk in adults and children with inflammatory bowel disease (IBD) and inflammatory rheumatic disease (IRD) treated with immunosuppressive biologics in Denmark, including temporal trends and risk stratification by TB infection status and country of birth. METHODS: Patients diagnosed with IBD or …
Erratum to "Is stapled Kono-S anastomosis a protective factor against postoperative endoscopic recurrence in Crohn disease? A single-center, retrospective cohort study" [J Gastrointest Surg 29 (2025) 101941]
Publication Year: 2025 Source: J Gastrointest Surg PMID: 40550461
No Abstract
British Society of Gastroenterology guidelines on inflammatory bowel disease in adults: 2025
Publication Year: 2025 Source: Gut PMID: 40550582 DOI: 10.1136/gutjnl-2024-334395
No Abstract
Beyond the guideline: lessons in leadership, limits and legacy from the BSG IBD process
Publication Year: 2025 Source: Gut PMID: 40550584 DOI: 10.1136/gutjnl-2025-336129
No Abstract
Association rule mining of the human gut microbiome
Publication Year: 2025 Source: Sci China Life Sci PMID: 40550997 DOI: 10.1007/s11427-024-2865-1
The human gut carries a vast and diverse microbial community that is essential for human health. Understanding the structure of this complex community is a crucial step toward comprehending human-microbiome interactions. Traditional co-occurrence and correlation analyses typically focus on pairwise relationships and ignore higher-order relationships. Association rule mining (ARM) is …
Comment on "Switching to Subcutaneous Infliximab Maintenance Therapy is Effective in Patients with Inflammatory Bowel Disease"
Publication Year: 2025 Source: Dig Dis Sci PMID: 40551056
No Abstract
Telecare enhances the retention of patients with inflammatory bowel disease within a tertiary care inflammatory bowel disease center
Publication Year: 2025 Source: J Telemed Telecare PMID: 40551537 DOI: 10.1177/1357633X251349383
BackgroundTelecare is increasingly important in managing patients with chronic diseases, including patients with inflammatory bowel disease (IBD). This study evaluates the impact of telecare on patient retention and access to tertiary care for patients with IBD.MethodsWe analyzed patient data from a tertiary care IBD center, comparing patterns pre-COVID (January 2018 …
The Vitamin D and IBD Nexus: Immune Links and Therapeutic Prospects
Publication Year: 2025 Source: J Am Nutr Assoc PMID: 40551677 DOI: 10.1080/27697061.2025.2518117
No Abstract
Cholecalciferol (vitamin D3): efficacy, safety, and implications in public health
Publication Year: 2025 Source: Front Nutr PMID: 40551736
Vitamin D(3) (cholecalciferol) is a fat-soluble secosteroid with essential roles in calcium-phosphorus metabolism, bone health, and an expanding range of extraskeletal processes. Upon synthesis in the skin via ultraviolet B exposure or ingestion from dietary sources, cholecalciferol is hydroxylated in the liver and kidneys to form its active metabolite, calcitriol …
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