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Parenteral nutrition: a life-saving intervention for 4 months in short bowel syndrome-a case report and review of the literature

Publication Year: 2024 Source: J Med Case Rep PMID: 38509559

No Abstract

scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases

Publication Year: 2024 Source: Genome Med PMID: 38509600

No Abstract

Role of PAR1 -506 deletion/insertion polymorphism in primary sclerosing cholangitis

Publication Year: 2024 Source: Hepatol Res PMID: 38509789 DOI: 10.1111/hepr.14035

AIM: Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by inflammation of the intra- and extrahepatic bile ducts. Pathogenesis of PSC is still enigmatic but is likely to be multifactorial. Recently, we identified an interleukin-6 (IL-6)-dependent signal transducer and activator of transcription 3 (STAT3) activation in CD4(+) …

Histologic assessments in ulcerative colitis: the evidence behind a new endpoint in clinical trials

Publication Year: 2024 Source: Expert Rev Gastroenterol Hepatol PMID: 38509826

No Abstract

A protective effect of inflammatory bowel disease on the severity of sclerosing cholangitis

Publication Year: 2024 Source: Front Immunol PMID: 38510236 DOI: 10.3389/fimmu.2024.1307297

BACKGROUND: Primary sclerosing cholangitis (PSC) is a chronic liver disease marked by inflammation of the bile ducts and results in the development of strictures and fibrosis. A robust clinical correlation exists between PSC and inflammatory bowel disease (IBD). At present, published data are controversial, and it is yet unclear whether …

Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach

Publication Year: 2024 Source: Front Immunol PMID: 38510241 DOI: 10.3389/fimmu.2024.1353402

BACKGROUND: Understanding the molecular pathogenesis of inflammatory bowel disease (IBD) has led to the discovery of new therapeutic targets that are more specific and effective. Our aim was to explore the molecular pathways and genes involved in IBD pathogenesis and to identify new therapeutic targets and novel biomarkers that can …

Elucidating the role of TWIST1 in ulcerative colitis: a comprehensive bioinformatics and machine learning approach

Publication Year: 2024 Source: Front Genet PMID: 38510272

No Abstract

Incidence of Low Seroimmunity to Hepatitis B Virus in Children with Inflammatory Bowel Disease: A Single Center Experience

Publication Year: 2024 Source: Pediatr Gastroenterol Hepatol Nutr PMID: 38510586 DOI: 10.5223/pghn.2024.27.2.104

No Abstract

Bioinspired and biomimetic strategies for inflammatory bowel disease therapy

Publication Year: 2024 Source: J Mater Chem B PMID: 38511264 DOI: 10.1039/d3tb02995f

Inflammatory bowel disease (IBD) is an idiopathic chronic inflammatory bowel disease with high morbidity and an increased risk of cancer or death, resulting in a heavy societal medical burden. While current treatment modalities have been successful in achieving long-term remission and reducing the risk of complications, IBD remains incurable. Nanomedicine …

RATE OF INFECTION (TUBERCULOSIS) IN BRAZILIANS IBD PRIVATE PATIENTS: FOLLOW-UP 15 YEARS

Publication Year: 2024 Source: Arq Gastroenterol PMID: 38511796 DOI: 10.1590/S0004-2803.24612023-148

BACKGROUND: Latent tuberculosis (LTB) is a condition where the patient is infected with Mycobacterium tuberculosis but does not develop active TB. There's a possibility of tuberculosis (TB) activation following the introduction of anti-TNFs. OBJECTIVE: To assess the risk of biological therapy inducing LTB during inflammatory bowel diseases (IBD) treatment over …

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