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Mucoadhesive Mesalamine Prodrug Nanoassemblies to Target Intestinal Macrophages for the Treatment of Inflammatory Bowel Disease

Publication Year: 2024 Source: ACS Nano PMID: 38867457 DOI: 10.1021/acsnano.4c05544

While mesalamine, a 5-aminosalicylic acid (5-ASA), is pivotal in the management of inflammatory bowel disease (IBD) through both step-up and top-down approaches in clinical settings, its widespread utilization is limited by low bioavailability at the desired site of action due to rapid and extensive absorption in the upper gastrointestinal (GI) …

'Food doesn't control me anymore!' psychosocial experiences during dietary management in adults with inflammatory bowel disease: A qualitative study

Publication Year: 2024 Source: J Clin Nurs PMID: 38867610

No Abstract

A review on current advancement in zebrafish models to study chronic inflammatory diseases and their therapeutic targets

Publication Year: 2024 Source: Heliyon PMID: 38867970 DOI: 10.1016/j.heliyon.2024.e31862

Chronic inflammatory diseases are caused due to prolonged inflammation at a specific site of the body. Among other inflammatory diseases, bacterial meningitis, chronic obstructive pulmonary disease (COPD), atherosclerosis and inflammatory bowel diseases (IBD) are primarily focused on because of their adverse effects and fatality rates around the globe in recent …

Full title: "Hopes, worries and expectations" experiences of pregnancy with inflammatory bowel disease: An interpretative phenomenological analysis study

Publication Year: 2024 Source: Heliyon PMID: 38868041 DOI: 10.1016/j.heliyon.2024.e31954

BACKGROUND AND AIMS: Inflammatory Bowel Disease (IBD) affects many women of childbearing age. High levels of voluntary childlessness and high levels of pregnancy-related fears have been reported amongst these patients in several quantitative studies. We investigated the lived experiences of pregnant patients to better understand decision-making processes around family planning. …

CORRECTING MODEL MISSPECIFICATION IN RELATIONSHIP ESTIMATES

Publication Year: 2024 Source: bioRxiv PMID: 38868169 DOI: 10.1101/2024.05.13.594005

The datasets of large genotyping biobanks and direct-to-consumer genetic testing companies contain many related individuals. Until now, it has been widely accepted that the most distant relationships that can be detected are around fifteen degrees (approximately 8 (th) cousins) and that practical relationship estimates have a ceiling around ten degrees …

Acute Abdominal Pain and Rapidly Accumulating Ascites as an Unusual Presentation of Salmonella Typhi: A Case Report

Publication Year: 2024 Source: Cureus PMID: 38868285

No Abstract

Summary of the best evidence on self-management support schemes for patients with inflammatory bowel disease based on mobile health systems

Publication Year: 2024 Source: Digit Health PMID: 38868366

No Abstract

Rare presentations of small bowel endometriosis

Publication Year: 2024 Source: DEN Open PMID: 38868705

No Abstract

Early and Sustained Symptom Control with Mirikizumab in Patients with Ulcerative Colitis in the Phase 3 LUCENT Programme

Publication Year: 2024 Source: J Crohns Colitis PMID: 38869019

No Abstract

Risk Factors for Persistent Postoperative Opioid Use After Surgery for IBD: An Observational Cohort Study

Publication Year: 2024 Source: Dis Colon Rectum PMID: 38869466 DOI: 10.1097/DCR.0000000000003258

BACKGROUND: Patients with IBD are at increased risk of persistent opioid use, wherein surgery plays an important role. OBJECTIVE: Identify risk factors for persistent postoperative opioid use in patients with IBD undergoing GI surgery and describe in-hospital postoperative opioid treatment. DESIGN: This was a retrospective observational cohort study. ORs for …

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