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A likelihood-based approach to estimating and testing for isolation by distance
Publication Year: 2004 Source: Evolution PMID: 15446435 DOI: 10.1111/j.0014-3820.2004.tb00466.x
BACKGROUND AND PURPOSE: The SNP R30Q (rs1248696) within the discs large homolog 5 (DLG5) gene has been associated with inflammatory bowel disease (IBD). In this study, we examined the genetic association of another DLG5 SNP P1371Q (rs2289310) with IBD and its interaction with R30Q in disease susceptibility. METHODS: A total …
Assessment of thrombin-activatable fibrinolysis inhibitor (TAFI) plasma levels in inflammatory bowel diseases
Publication Year: 2004 Source: Am J Gastroenterol PMID: 15447757 DOI: 10.1111/j.1572-0241.2004.30203.x
BACKGROUND: Environmental factors, including socioeconomic status, may affect inflammatory bowel disease (IBD). There is a paucity of data on the epidemiology of IBD among patients of low socioeconomic status. AIM: To examine the epidemiologic features of IBD among African-American, Hispanic, and Caucasian patients from a county hospital, where the majority …
Thromboembolism--an important manifestation of inflammatory bowel disease
Publication Year: 2004 Source: Am J Gastroenterol PMID: 15447758 DOI: 10.1111/j.1572-0241.2004.40923.x
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Depressive symptoms and inflammatory bowel disease in children and adolescents: a cross-sectional study
Publication Year: 2004 Source: J Pediatr Gastroenterol Nutr PMID: 15448431 DOI: 10.1097/00005176-200410000-00017
BACKGROUND: A child- and adolescent-generated IBD quality-of-life index was designed to be descriptive (to be used to assess the overall impact of IBD on individual patients), and evaluative (to be used as an outcome measure in clinical trials). METHODS: Item-generation and item-reduction interviews with 82 patients with IBD aged 8 …
Gastrin releasing peptide receptor expression is decreased in patients with Crohn's disease but not in ulcerative colitis
Publication Year: 2004 Source: J Clin Pathol PMID: 15452158 DOI: 10.1136/jcp.2003.014993
BACKGROUND: Infliximab appears to be efficacious in the treatment of pediatric Crohn disease (CD). There are few large-scale pediatric studies on the complications of infliximab therapy. METHODS: A retrospective review of all infliximab infusions administered to IBD patients at a tertiary children's hospital was undertaken. Data was obtained from an …
[Immunosuppressive therapy for inflammatory bowel disease: consensus by the Austrian working group on IBD]
Publication Year: 2004 Source: Z Gastroenterol PMID: 15455280 DOI: 10.1055/s-2004-813500
The breakdown of tolerance to autologous bacterial flora has been implicated as a major factor contributing to the initiation and perpetuation of chronic inflammation in inflammatory bowel diseases (IBD). To test whether bacterial DNA is at the origin of inflammation in IBD, we have examined the response of lamina propria …
Inflammatory bowel diseases as an intermediate stage between normal and cancer: a FTIR-microspectroscopy approach
Publication Year: 2004 Source: Biopolymers PMID: 15457432 DOI: 10.1002/bip.20154
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Patients' experiences of an open access follow up arrangement in managing inflammatory bowel disease
Publication Year: 2004 Source: Qual Saf Health Care PMID: 15465941 DOI: 10.1136/qhc.13.5.374
In human food allergy, with or without concurrent atopy, there may be significant increases in serum allergen-specific IgE. Serological methods have been tried but are not currently recommended for diagnosis of suspected food allergy in dogs. The aim of this study was to investigate humoral immune responses to food antigens …
Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1a gene
Publication Year: 2004 Source: Br J Pharmacol PMID: 15466445 DOI: 10.1038/sj.bjp.0705982
BACKGROUND: 6-Thioguanine (6-TG) has been used as an alternative thiopurine for inflammatory bowel disease (IBD) patients not responsive to or intolerant of azathioprine (AZA) and 6-mercaptopurine (6-MP). 6-TG-related hepatotoxicity, including liver biochemistry value elevations, sinusoidal collagen deposition on electron microscopy, and veno-occlusive disease, have been described related to its use …
Pharmacological properties of traditional medicine (XXIX): effect of Hange-shashin-to and the combinations of its herbal constituents on rat experimental colitis
Publication Year: 2004 Source: Biol Pharm Bull PMID: 15467203 DOI: 10.1248/bpb.27.1599
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