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Isobutyryl-CoA dehydrogenase deficiency: isobutyrylglycinuria and ACAD8 gene mutations in two infants
Publication Year: 2004 Source: J Inherit Metab Dis PMID: 15505379 DOI: 10.1023/B:BOLI.0000045798.12425.1b
Not found
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
Publication Year: 2004 Source: Genes Immun PMID: 15505619 DOI: 10.1038/sj.gene.6364123
Not found
Fatigue in patients with primary sclerosing cholangitis
Publication Year: 2004 Source: Scand J Gastroenterol PMID: 15513335 DOI: 10.1080/00365520410003434
BACKGROUND: Patients with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) may have an increased risk of developing colorectal cancer (CRC) after liver transplantation (LT). We evaluated our patients with PSC after LT to identify risk factors for CRC and its impact on survival. PATIENTS AND METHODS: A total …
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
Publication Year: 2004 Source: Proc Natl Acad Sci U S A PMID: 15514019 DOI: 10.1073/pnas.0407180101
OBJECTIVE: We measured the mucosal levels of interleukin 1beta (IL-1beta), IL-2, IL-6, and IL-8 in affected segments of radiation-induced proctosigmoiditis and compared these with the levels in normal controls and inflammatory bowel disease (IBD) patients. METHODS: Thirteen patients with histologically proven radiation proctosigmoiditis, 32 patients with active ulcerative colitis (UC), …
Inflammatory bowel disease in Ashkenazi Jews: implications for familial colorectal cancer
Publication Year: 2004 Source: Fam Cancer PMID: 15516846 DOI: 10.1007/s10689-004-9548-9
Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) that are characterized by chronic intestinal inflammation and a constant influx of leukocytes mediated by pro-inflammatory cytokines and chemokines. The intestinal expression of the CXCR1-binding chemokines IL-8/CXCL8 and GCP-2/CXCL6 and the participation of immunocompetent cells in IBD were …
Inflammatory bowel disease reveals the kinase activity of KSR1
Publication Year: 2004 Source: J Clin Invest PMID: 15520853 DOI: 10.1172/JCI23441
BACKGROUND: This study was designed to develop and validate the ADAPT (Assessment of the Demand for Additional Psychological Treatment), a questionnaire assessing the demand for disease-oriented counseling (DOC), integrated psychosomatic care (IPC), and psychotherapy (PT) in chronically ill patients on the example of inflammatory bowel diseases (IBDs). METHODS: After its …
hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells
Publication Year: 2004 Source: Gastroenterology PMID: 15521010 DOI: 10.1053/j.gastro.2004.07.024
Not found
Stat6(null phenotype) human lymphocytes exhibit increased apoptosis
Publication Year: 2004 Source: J Surg Res PMID: 15522309 DOI: 10.1016/j.jss.2004.05.004
Comment in J Clin Microbiol. 2004 Nov;42(11):5432; author reply 5432-3. There is renewed enthusiasm for exploring the possibility that Mycobacterium paratuberculosis may be causative in Crohn's disease (CD). We aimed to determine whether CD subjects are more likely to be M. paratuberculosis seropositive than controls. Using our population-based University of …
Intraoperative continuous external bile drainage during pancreaticoduodenectomy
Publication Year: 2004 Source: Surg Today PMID: 15526126 DOI: 10.1007/s00595-004-2854-x
GOALS: We sought to determine the yield of stool analysis for bacterial culture, ova and parasites, and Clostridium difficile toxin in suspected relapses of inflammatory bowel disease (IBD). BACKGROUND: The diagnostic yield of such stool studies has not been examined recently in the United States. STUDY: The medical records of …
Effects of dermatan sulfate derivatives on platelet surface P-selectin expression and protein C activity in blood of inflammatory bowel disease patients
Publication Year: 2004 Source: World J Gastroenterol PMID: 15526370 DOI: 10.3748/wjg.v10.i23.3485
Biologic therapies, namely antibodies against tumor necrosis factor-alpha (TNF- alpha) or its receptors, have been recently introduced for the treatment of patients with inflammatory bowel disease (IBD). In the present study the effects of cloricromene, an agent with known antithrombotic actions and with demonstrated anti-TNF- alpha activity were investigated in …
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