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Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1
Publication Year: 2004 Source: J Hepatol PMID: 15123348 DOI: 10.1016/j.jhep.2003.11.009
BACKGROUND: an item to consider in analyzing a healthcare model for a population group suffering from chronic disease is necessary health-care resources, their use, and their rating by end-users. Regarding inflammatory bowel disease (IBD), healthcare resources used by patients are numerous and varied, and yet they have been never assessed. …
Bacterial flagellin is a dominant antigen in Crohn disease
Publication Year: 2004 Source: J Clin Invest PMID: 15124021 DOI: 10.1172/JCI20295
Comment in Cell. 2003 Nov 14;115(4):370-2. Transcription start site selection in eukaryotes is mediated through combinations of the TATA, initiator (Inr), and downstream promoter elements (DPE). In Trichomonas vaginalis, a parabasalian flagellate thought to represent an ancient eukaryote lineage, the Inr appears to be solely responsible for start site selection …
Health-related quality of life in patients with inflammatory bowel disease five years after the initial diagnosis
Publication Year: 2004 Source: Scand J Gastroenterol PMID: 15125469 DOI: 10.1080/00365520310008386
BACKGROUND: Environmental exposures in early life have been implicated in the aetiology of inflammatory bowel disease (IBD). Siblings are used as proxy markers to characterize patterns of exposure relevant to the risk of IBD. METHODS: Some 15,823 patients with ulcerative colitis and 12,668 with Crohn disease from the Swedish In-patient …
Detection of specific IgE antibodies to nafamostat mesilate as an indication of possible adverse effects of leukocytapheresis using nafamostat mesilate as anticoagulant
Publication Year: 2004 Source: Ther Apher Dial PMID: 15128019 DOI: 10.1111/j.1526-0968.2004.00086.x
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Predictors of alternative and complementary medicine use in inflammatory bowel disease: do measures of conventional health care utilization relate to use?
Publication Year: 2004 Source: Am J Gastroenterol PMID: 15128356 DOI: 10.1111/j.1572-0241.2004.30033.x
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Platelets in inflammatory bowel disease: clinical, pathogenic, and therapeutic implications
Publication Year: 2004 Source: Am J Gastroenterol PMID: 15128364 DOI: 10.1111/j.1572-0241.2004.04129.x
OBJECTIVES: Venous thromboembolism has been associated with inflammatory bowel disease (IBD). We sought to describe the clinical features, acquired and congenital risk factors, and outcomes of venous thromboembolism in IBD. METHODS: All patients with confirmed IBD and deep venous thrombosis (DVT) or pulmonary embolism (PE) at our institution between 1991 …
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells
Publication Year: 2004 Source: Gastroenterology PMID: 15131796 DOI: 10.1053/j.gastro.2004.02.004
INTRODUCTION: Pediatric studies on immunogenicity of infliximab have not been published. The aim of the study was to evaluate the prevalence of human antichimeric antibody (HACA), relationship to infusion reactions (IR), and the role of concomitant immunomodulatory therapies. METHODS: An inflammatory bowel disease (IBD) database was queried, and a retrospective …
Powerful allele sharing statistics for nonparametric linkage analysis
Publication Year: 2004 Source: Hum Hered PMID: 15133312 DOI: 10.1159/000077389
Not found
Opposite evolution in incidence of Crohn's disease and ulcerative colitis in Northern France (1988-1999)
Publication Year: 2004 Source: Gut PMID: 15138211 DOI: 10.1136/gut.2003.025346
OBJECTIVE: An assessment of oral symptoms and signs in patients with inflammatory bowel disease (IBD). METHODS: Fifty-four patients with IBD, 34 with Crohn's disease (CD) and 20 with ulcerative colitis (UC) participated in the study. Forty-two patients without gastrointestinal disease or complaints attending the orthopedic clinic served as controls. Each …
Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County
Publication Year: 2004 Source: Gut PMID: 15138212 DOI: 10.1136/gut.2003.018515
BACKGROUND: Cytokines are essential mediators of the intestinal inflammation during active episodes of inflammatory bowel disease (IBD). Interleukin (IL)-12 and IL-17 are potent immunoregulatory cytokines whose roles in the pathogenesis of IBD are unknown. The aim of this study was to evaluate the colonic expression of IL-12 and IL-17 genes …
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