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Coping strategies and quality of life of adolescents with inflammatory bowel disease
Publication Year: 2004 Source: Qual Life Res PMID: 15233514 DOI: 10.1023/B:QURE.0000025598.89003.0c
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Proteomics and chronic inflammatory bowel diseases
Publication Year: 2004 Source: Pathol Res Pract PMID: 15237921 DOI: 10.1016/j.prp.2004.02.002
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon whose etiology is unknown. Small bowel involvement in UC is extraordinarily rare, and should make the clinician question the diagnosis. However, we present a case of a 38-year-old man with voluminous diarrhea following colectomy for well-documented UC; he was …
Mucosal T cells bearing TCRgammadelta play a protective role in intestinal inflammation
Publication Year: 2004 Source: J Immunol PMID: 15240735 DOI: 10.4049/jimmunol.173.2.1390
Comment in Inflamm Bowel Dis. 2005 Jan;11(1):79-80. BACKGROUND: Recent advances in gadolinium-enhanced magnetic resonance imaging (G-MRI) have been developed to enhance the resolution of the intestinal mucosa and facilitate the differentiation of ulcerative colitis (UC) from Crohn's disease (CD). The objective of this study is to apply this technology in …
CD4+ T cells from IL-10-deficient mice transfer susceptibility to NSAID-induced Rag colitis
Publication Year: 2004 Source: Am J Physiol Gastrointest Liver Physiol PMID: 15246967 DOI: 10.1152/ajpgi.00527.2003
OBJECTIVES: Budesonide is a corticosteroid with low systemic bioavailability because of its high first-pass metabolism in the liver. In this paediatric, randomized, double-blind, double-dummy, controlled, multicentre trial, the safety and efficacy of budesonide versus prednisolone were evaluated in children with active Crohn's disease. METHODS: Forty-eight children, aged 6-16 years, with …
Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease
Publication Year: 2004 Source: Gut PMID: 15247179 DOI: 10.1136/gut.2003.032896
OBJECTIVES: To assess the prevalence and determinants of alternative medicine (AM) use in gastroenterology outpatients and those with inflammatory bowel disease (IBD). METHODS: An 80-item questionnaire, addressing symptoms, general health, quality of life, and AM use, was administered and analyzed using logistic regression. RESULTS: 52.5% of 341 participants used AM …
Iron, anaemia, and inflammatory bowel diseases
Publication Year: 2004 Source: Gut PMID: 15247190 DOI: 10.1136/gut.2003.035758
Ulcerative colitis and Crohn's disease are chronic gastrointestinal diseases that affect patients in the prime of their lives. Because inflammatory bowel disease (IBD) patients generally live a normal lifespan, chronic medical therapy for IBD must be tolerable, simple to adhere to, and have as few side effects as possible. This …
Digital radiogrammetry of the hand in a pediatric and adolescent Dutch Caucasian population: normative data and measurements in children with inflammatory bowel disease and juvenile chronic arthritis
Publication Year: 2004 Source: Calcif Tissue Int PMID: 15255071 DOI: 10.1007/s00223-003-0020-x
Crohn's disease, ulcerative colitis, and pouchitis are caused by overly aggressive immune responses to a subset of commensal (nonpathogenic) enteric bacteria in genetically predisposed individuals. Clinical and experimental studies suggest that the relative balance of aggressive and protective bacterial species is altered in these disorders. Antibiotics can selectively decrease tissue …
Differential expression of connective tissue growth factor in inflammatory bowel disease
Publication Year: 2004 Source: Digestion PMID: 15256831 DOI: 10.1159/000079845
Comment in Gastroenterology. 2003 Apr;124(4):1145-9. BACKGROUND & AIMS: NOD2, a member of the NOD1/Apaf-1 family, was recently identified as the first susceptibility gene for Crohn's disease. The aim of this report was to describe the regulation and functional significance of NOD2 expression in intestinal epithelial cells. METHODS: Expression of NOD2 …
Enteric infection in relapse of inflammatory bowel disease: importance of microbiological examination of stool
Publication Year: 2004 Source: Eur J Gastroenterol Hepatol PMID: 15256979 DOI: 10.1097/01.meg.0000131040.38607.09
BACKGROUND AND AIM: Simple mucosal biopsy criteria proposed by authors reliably differentiate idiopathic inflammatory bowel disease (IBD) from other forms of colitis (non-IBD) and Crohn's disease involving the colon (CD) from ulcerative colitis (UC). The aim of this study is to investigate the reproducibility of these criteria. METHODS: Three established …
Canine inflammatory bowel disease: retrospective analysis of diagnosis and outcome in 80 cases (1995-2002)
Publication Year: 2004 Source: J Small Anim Pract PMID: 15266855 DOI: 10.1111/j.1748-5827.2004.tb00245.x
Long-chain n-3 PUFA in fish oil have modulating effects on inflammatory responses. The aim of this open pilot study was to investigate whether duodenal seal oil administration would benefit patients with inflammatory bowel disease (IBD). Seal oil (10 mL) was administered three times a day directly into the distal part …
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