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HLA disparity determines disease activity through pregnancy in women with inflammatory bowel disease
Publication Year: 2004 Source: Am J Gastroenterol PMID: 15307871 DOI: 10.1111/j.1572-0241.2004.30472.x
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Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: increased prevalence of ASCA and pANCA
Publication Year: 2004 Source: Digestion PMID: 15308872 DOI: 10.1159/000080081
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[The prevalence of radiographic sacroiliitis in patients affected by inflammatory bowel disease with inflammatory low back pain]
Publication Year: 2004 Source: Reumatismo PMID: 15309219 DOI: 10.4081/reumatismo.2004.110
Inflammatory bowel diseases (IBD), commonly referred to as Crohn's disease and ulcerative colitis are chronic aggressive disorders which share many similarities concerning pathomechanism and clinical course, but have very distinct features. Both entities are mainly located in areas with high bacterial concentrations, such as the terminal ileum and cecum in …
Improved diagnostic accuracy of inflammatory bowel disease: a clinicopathological collaborative approach
Publication Year: 2004 Source: Tech Coloproctol PMID: 15309652 DOI: 10.1007/s10151-004-0070-8
The treatment of children and families affected by pediatric IBD requires an awareness of the diverse psychobiologic effects of the disorder over the course of child, adolescent [53], and adult development [52]. Optimal treatment requires careful coordination of various medical, educational, and rehabilitative services and concerned, empathetic, continuity of care …
Fecal lactoferrin: a new parameter to monitor infliximab therapy
Publication Year: 2004 Source: Dig Dis Sci PMID: 15309897 DOI: 10.1023/b:ddas.0000034568.69407.47
Random Forest is a prediction technique based on growing trees on bootstrap samples of data, in conjunction with a random selection of explanatory variables to define the best split at each node. In the case of a quantitative outcome, the tree predictor takes on a numerical value. We applied Random …
Guidelines for treatment of ulcerative colitis in children
Publication Year: 2004 Source: Pediatr Int PMID: 15310325 DOI: 10.1111/j.1442-200x.2004.01924.x
Two polymorphisms of the CTLA-4 gene were genotyped in 232 sibling pairs affected with multiple sclerosis (MS) from 185 families. The CTLA-4 polymorphisms genotyped were a 3' untranslated (AT)(n) microsatellite and an alanine/threonine RFLP of exon 1. There was no evidence observed for linkage by either identity-by-descent (ibd) or identity-by-state …
Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease
Publication Year: 2004 Source: Am J Surg Pathol PMID: 15316320 DOI: 10.1097/01.pas.0000128665.12063.97
Comment in Am J Gastroenterol. 2004 Feb;99(2):316-8. OBJECTIVES: Three single nucleotide polymorphisms (SNPs) in CARD15 have been independently associated with Crohn's disease (CD). Since nothing is known about the transmission of these variants within families, this was the subject of our study in Flemish patients with inflammatory bowel disease (IBD) …
Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease
Publication Year: 2004 Source: Pharmacoepidemiol Drug Saf PMID: 15317038 DOI: 10.1002/pds.926
The case records of 80 dogs in which idiopathic inflammatory bowel disease (IBD) had been diagnosed were reviewed, and owners were contacted for follow-up information using a telephone questionnaire. The types of IBD encountered were lymphocytic (n=6), lymphocytic-plasmacytic (n=38), eosinophilic (n=6) and mixed inflammation (n=30). Prednisolone, sulphasalazine, metronidazole and tylosin …
Lumbar spine bone mineral density at diagnosis and during follow-up in children with IBD
Publication Year: 2004 Source: J Clin Densitom PMID: 15319499 DOI: 10.1385/jcd:7:3:290
OBJECTIVE: To investigate the consequences of having a chronic digestive disorder on the social position of adolescents. METHODS: Five diagnostic groups, including inflammatory bowel disease (IBD), chronic liver diseases, congenital digestive disorders, coeliac disease and food allergy (total n = 758, ages 12-25 years), were each compared with a population-based …
Diagnostic role of upper gastrointestinal endoscopy in pediatric inflammatory bowel disease
Publication Year: 2004 Source: J Pediatr Gastroenterol Nutr PMID: 15319625 DOI: 10.1097/00005176-200409000-00006
Crohn disease and ulcerative colitis are two subphenotypes of inflammatory bowel disease (IBD), a complex disorder resulting from gene-environment interaction. We refined our previously defined linkage region for IBD on chromosome 10q23 and used positional cloning to identify genetic variants in DLG5 associated with IBD. DLG5 encodes a scaffolding protein …
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