Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease
Publication Year: 2003 Source: J Immunol PMID: 14568967 DOI: 10.4049/jimmunol.171.9.4868
INTRODUCTION: Several new derivatives of sulphasalazine that make use of its active moiety, 5-aminosalicylic acid (5-ASA), have been introduced for the treatment of inflammatory bowel disease (IBD). In rats short term intravenous administration of 5-ASA has been associated with nephrotoxicity. A number of cases of nephrotoxicity have been reported recently …
White cell scanning for inflammatory bowel disease: are biochemical markers useful referral criteria?
Publication Year: 2003 Source: Nucl Med Commun PMID: 14569168 DOI: 10.1097/00006231-200311000-00004
The neurokinin (NK) receptors, NK(1) and NK(2), which are activated by substance P (SP) and NKA, have been identified as potential therapeutic targets in irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Here we have investigated the effects of a novel dual NK(1) and NK(2) receptor antagonist, namely DNK333 …
Genetics of inflammatory bowel diseases--past, present, and future
Publication Year: 2003 Source: Dig Dis PMID: 14571107 DOI: 10.1159/000073241
The role of nutritional intervention in inflammatory bowel disease (IBD) is twofold: first, as primary therapy for patients with acute Crohn's disease; second, as an invaluable adjunctive therapy for the correction and maintenance of nutritional status for both patients with Crohn's disease and those with ulcerative colitis. Careful nutritional monitoring …
Rationale for probiotic and antibiotic treatment strategies in inflammatory bowel diseases
Publication Year: 2003 Source: Dig Dis PMID: 14571109 DOI: 10.1159/000073243
BACKGROUND & AIMS: Recently, a number of animal models for different aspects of inflammatory bowel disease (IBD) have been developed. The aim of this study was to use one of these to determine whether particular, ostensibly innocuous, intestinal bacteria could provoke or exacerbate IBD. METHODS: Conventionally reared C.B17 SCID mice …
New diagnostic avenues in inflammatory bowel diseases. Capsule endoscopy, magnetic resonance imaging and virtual enteroscopy
Publication Year: 2003 Source: Dig Dis PMID: 14571110 DOI: 10.1159/000073244
Several aspects of IBD overlap between pediatric and adult population. Those include nutritional issues, bone density, and medical and surgical therapies. Some aspects like natural course of the disease, and epidemiology and genetics are more easily examined and researched in the pediatric population. Others like pubertal and growth delay, and …
Biological therapy in IBD. Anti-tumor necrosis factor-alpha and others
Publication Year: 2003 Source: Dig Dis PMID: 14571115 DOI: 10.1159/000073249
The evolving medical armamentarium holds promise for more precise and effective therapies for IBD. The experience with anti-TNF therapy, particularly infliximab, illustrates the potential efficacy of therapies targeted at specific mediators or pathways involved in the pathogenesis. Advances in molecular technology have enabled the development of novel and potentially effective …
Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study
Publication Year: 2003 Source: J Pediatr PMID: 14571234 DOI: 10.1067/s0022-3476(03)00444-x
BACKGROUND: Linkage data have now identified several inflammatory bowel disease (IBD) susceptibility loci but these data have not been consistently replicated in independent studies. One potential explanation for this is the possibility that patients enrolled in such studies may have been erroneously classified with respect to their diagnosis. AIMS: To …
No evidence for involvement of IL-4R and CD11B from the IBD1 region and STAT6 in the IBD2 region in Crohn's disease
Publication Year: 2003 Source: Eur J Hum Genet PMID: 14571275 DOI: 10.1038/sj.ejhg.5201058
Not found
Hyperhomocystinemia in children with inflammatory bowel disease
Publication Year: 2003 Source: J Pediatr Gastroenterol Nutr PMID: 14581802 DOI: 10.1097/00005176-200311000-00016
To determine the genetic etiology of complex diseases, a common study design is to recruit affected sib/relative pairs (ASP/ARP) and evaluate their genome-wide distribution of identical by descent (IBD) sharing using a set of highly polymorphic markers. Other attributes or environmental exposures of the ASP/ARP, which are thought to affect …
Age and family history at presentation of pediatric inflammatory bowel disease
Publication Year: 2003 Source: J Pediatr Gastroenterol Nutr PMID: 14581806 DOI: 10.1097/00005176-200311000-00020
Not found
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide