Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Genome sharing in large pedigrees: multiple imputation of ibd for linkage detection
Publication Year: 2003 Source: Hum Hered PMID: 14614245 DOI: 10.1159/000073739
Within the past decade, knowledge of the molecular basis of inflammatory bowel disease (IBD), including Crohn disease (CD) and ulcerative colitis, has advanced owing to the explosive growth of research involving the human genome. Furthermore, a shared interest between molecular biologists and clinical researchers has contributed to an emerging understanding …
The identity by descent process along the chromosome
Publication Year: 2003 Source: Hum Hered PMID: 14614246 DOI: 10.1159/000073740
Inflammatory bowel disease (IBD), while a popular diagnosis, may not occur as commonly as it is diagnosed. It is a diagnosis of exclusion, meaning that it is important to eliminate diseases that mimick it. Dietary intolerance or allergy in particular, can have the same clinical and histologic appearance as IBD. …
Targeting of costimulatory molecules as a therapeutic approach in inflammatory bowel disease
Publication Year: 2003 Source: BioDrugs PMID: 14614763 DOI: 10.2165/00063030-200317060-00003
Not found
Histologic features of mycophenolate mofetil-related colitis: a graft-versus-host disease-like pattern
Publication Year: 2003 Source: Int J Surg Pathol PMID: 14615824 DOI: 10.1177/106689690301100406
OBJECTIVE: To validate bio-electric impedance spectroscopy (BIS) by comparison with other methods for determination of body water compartments in stable subjects with an ileostomy and no or minor small bowel resection for inflammatory bowel disease (IBD). SUBJECTS: Twenty-one subjects were included, age range 36-65 y (female/male=12/9), Crohn's disease (CD), n=14, …
Contrasting activity of cytosin-guanosin dinucleotide oligonucleotides in mice with experimental colitis
Publication Year: 2003 Source: Clin Exp Immunol PMID: 14616780 DOI: 10.1046/j.1365-2249.2003.02288.x
The use of biologics has promising potential in the treatment of inflammation. Studies with cultured cells and mouse models of disease have ascribed proinflammatory and anti-inflammatory functions to oncostatin M (OSM) and the related cytokine, interleukin-6 (IL-6). Here, we examined the effect of systemic administration of adenoviral (Ad) vectors encoding …
Inflammatory bowel disease versus irritable bowel syndrome: a hospital-based, case-control study of disease impact on quality of life
Publication Year: 2003 Source: Scand J Gastroenterol PMID: 14621276 DOI: 10.1080/00365520310004524
OBJECTIVE: We sought to identify central loci that activate in response to visceral stimuli (stool and pain). We had a particular interest in observing the anterior cingulate gyrus and frontal cortex in normals and in patients with intestinal disease, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). METHODS: …
Colorectal cancer detection by colonoscopy in a Swedish county, 1979-95
Publication Year: 2003 Source: Scand J Gastroenterol PMID: 14621281 DOI: 10.1080/00365520310004911
OBJECTIVE AND DESIGN: This study aimed to determine if mucosal expression of the chemokines IL-8, RANTES and MCP-1 and the pro-inflammatory cytokines TNFalpha and IL-6 are elevated in patients with inflammatory bowel disease. MATERIALS AND SUBJECTS: Intestinal mucosa samples were obtained at the time of surgical resection, n = 16 …
Structural basis of core promoter recognition in a primitive eukaryote
Publication Year: 2003 Source: Cell PMID: 14622596 DOI: 10.1016/s0092-8674(03)00887-0
BACKGROUND: Identification of the genes causing inflammatory bowel disease (IBD) would enhance the understanding of and the treatment options for this disease. A hyperreactive immune response toward the intestinal flora has been implicated in the pathology of IBD. The natural resistance-associated macrophage protein (NRAMP) gene is believed to regulate macrophage …
Coagulation and fibrinolysis in inflammatory bowel disease and in giant cell arteritis
Publication Year: 2003 Source: Pathophysiol Haemost Thromb PMID: 14624048 DOI: 10.1159/000073850
Using the sample of 107 families with at least two asthmatic siblings, as part of the EGEA study, we have investigated linkage to asthma (or atopy) and genetic heterogeneity according to the presence/absence of atopy (or asthma) using two approaches: (1) the triangle test statistic (TTS), which considers the identical …
Bone density improves with disease remission in patients with inflammatory bowel disease
Publication Year: 2003 Source: Eur J Gastroenterol Hepatol PMID: 14624148 DOI: 10.1097/00042737-200312000-00003
Interleukin-1beta (IL-1beta) is a proinflammatory cytokine that plays a central role in inflammatory bowel disease (IBD). In order to elucidate the mechanism of motility disorders frequently observed in IBD, we investigated the long term effects of IL-1beta on rat ileal smooth muscle contractility by using an organ culture system. When …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide