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Prevalence and management of inflammatory bowel disease: a cross-sectional study from central England
Publication Year: 2003 Source: Eur J Gastroenterol Hepatol PMID: 14624149 DOI: 10.1097/00042737-200312000-00004
Comment in Gastroenterology. 2004 Mar;126(3):940-1; author reply 941-2. BACKGROUND & AIMS: Thioguanine (6-TG) has been studied as an alternative thiopurine in inflammatory bowel disease (IBD). Short-term safety and efficacy data were favorable. Experience with 6-TG in patients with acute lymphoblastic leukemia raised long-term safety concerns when implicated in nodular regenerative …
Strong telomerase activity of B lymphocyte from mesenteric lymph nodes of patients with inflammatory bowel disease
Publication Year: 2003 Source: Dig Dis Sci PMID: 14627360 DOI: 10.1023/a:1026107429546
The bewildering array of medications in the therapy of inflammatory bowel disease (IBD) often confounds the clinician in the choice of specific agents regarding the balance between safety and efficacy. This review surveys and evaluates currently available IBD therapies as well as those used in clinical trials of ulcerative colitis. …
Summary of Group 8: Development and extension of linkage methods
Publication Year: 2003 Source: Genet Epidemiol PMID: 14635171 DOI: 10.1002/gepi.10286
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Research on infectious bursal disease--the past, the present and the future
Publication Year: 2003 Source: Vet Microbiol PMID: 14637046 DOI: 10.1016/j.vetmic.2003.08.005
Geographic patterns of genetic diversity depend on a species' demographic properties in a given habitat, which may change over time. The rates at which patterns of diversity respond to changes in demographic properties and approach equilibrium are therefore pivotal in our understanding of spatial patterns of diversity. The brook charr …
A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management
Publication Year: 2003 Source: Am J Gastroenterol PMID: 14638335 DOI: 10.1111/j.1572-0241.2003.07696.x
Induction of colitis by acetic acid (AA) in the rat is widely used experimental model of inflammatory bowel disease (IBD) and ulcerations. AA as an irritant induces colitis involving infiltration of colonic mucosa with neutrophils and increased production of inflammatory mediators, such as hydrogen peroxide (H2O2), nitric oxide (NO), myeloperoxidase …
Lack of relationship of calcium and vitamin D intake to bone mineral density in premenopausal women with inflammatory bowel disease
Publication Year: 2003 Source: Am J Gastroenterol PMID: 14638350 DOI: 10.1111/j.1572-0241.2003.07676.x
OBJECTIVE: Little is known of the psychological well-being of youths diagnosed as having inflammatory bowel diseases (IBDs). Much of the literature available focuses on adults with IBD and those that focus on youths tend to use generic measures of health-related quality of life (QOL). The primary aim of this research …
A note on including phenotypic information from monozygotic twins in variance components QTL linkage analysis
Publication Year: 2003 Source: Ann Hum Genet PMID: 14641249 DOI: 10.1046/j.1529-8817.2003.00069.x
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The interleukin-25 gene located in the inflammatory bowel disease (IBD) 4 region: no association with inflammatory bowel disease
Publication Year: 2003 Source: Eur J Immunogenet PMID: 14641539 DOI: 10.1046/j.1365-2370.2003.00411.x
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD) of unknown pathogenesis, for which no curative treatment is currently available. Although the recent introduction of agents designed to neutralise tumour necrosis factor has been an important achievement towards the control of Crohn's disease, further development of more fundamental and …
Serum human cartilage glycoprotein 39 as a marker of arthritis associated with inflammatory bowel disease
Publication Year: 2003 Source: Ann Rheum Dis PMID: 14644865 DOI: 10.1136/ard.2002.004408
Comment in Am J Gastroenterol. 2006 Feb;101(2):403; author reply 403-4. BACKGROUND: Inflammatory bowel diseases (IBD) are characterized by an increased risk for venous and arterial thrombosis. Although the pathogenetic mechanisms of this predisposition are unclear, a possible role of inherited risk factors for thrombosis in determining this predisposition has been …
[Osteoporosis in inflammatory bowel disease - results of a survey among members of the German Crohn's and Ulcerative Colitis Association]
Publication Year: 2003 Source: Z Gastroenterol PMID: 14661123 DOI: 10.1055/s-2003-45280
1. Inflammatory bowel disease (IBD) is a condition that involves proinflammatory cytokines such as interleukins 1beta and 6 (ILs). In this disease, it has been shown that an abnormal microcirculatory system is implicated. 2. Therefore, the effects of in vivo treatment for three days with interleukins 1beta and 6 were …
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