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Tobacco consumption and disease duration are associated with fistulizing and stricturing behaviors in the first 8 years of Crohn's disease
Publication Year: 2003 Source: Am J Gastroenterol PMID: 12591056 DOI: 10.1111/j.1572-0241.2003.07240.x
Metallothionein (MT) expression in intestinal resection specimens from 41 patients with ulcerative colitis (UC) and 10 patients with Crohn's disease (CD ) was immunohistochemically studied by the avidin-biotin (ABC) method. In addition, the possible relationship of its expression with HLA-DR antigen expression, lymphocyte subpopulations and proliferation-associated indices was studied in …
Dual and selective antagonism of neurokinin NK(1) and NK(2) receptor-mediated responses in human colon mucosa
Publication Year: 2003 Source: Naunyn Schmiedebergs Arch Pharmacol PMID: 12595950 DOI: 10.1007/s00210-002-0671-6
Both celiac disease and inflammatory bowel disease (IBD) are characterized by chronic diarrhea and the presence of distinct (auto)antibodies. In the present study we wanted to determine the prevalence of serological markers for inflammatory bowel disease, i.e., perinuclear antineutrophil cytoplasmic antibodies (pANCA) and/or anti-Saccharomyces cerevisiae antibodies (ASCA), in 37 patients …
The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat
Publication Year: 2003 Source: Br J Pharmacol PMID: 12598422 DOI: 10.1038/sj.bjp.0705077
OBJECTIVE: To evaluate risk factors - notably drugs - for developing acute pancreatitis. METHODS: A population-based, case-control study, encompassing 1.4 million inhabitants aged 20-85 years from four regions in Sweden between 1 January 1995 and 31 May 1998. A total of 462 cases were hospitalised in surgical departments with their …
Differentiation of infectious bursal disease viruses by restriction enzyme analysis of RT-PCR amplified VP1 gene sequence
Publication Year: 2003 Source: Comp Immunol Microbiol Infect Dis PMID: 12602686 DOI: 10.1016/s0147-9571(02)00017-6
Inflammatory bowel diseases (IBDs; Crohn's disease (CD) and ulcerative colitis) are chronic inflammatory diseases leading to destruction of gastrointestinal tissue. They are characterized by an exaggerated immune response. In CD, an increased expression of T-helper-1 (Th1) cytokines was observed in which interleukin-12 (IL-12) seems to play a pivotal role. Different …
Recurrent myopericarditis in association with Crohn's disease
Publication Year: 2003 Source: J Intern Med PMID: 12603508 DOI: 10.1046/j.1365-2796.2003.01082.x
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The establishment of a national tissue bank for inflammatory bowel disease research in Canada
Publication Year: 2003 Source: Can J Gastroenterol PMID: 12605247 DOI: 10.1155/2003/589245
Between April 1998 and June 1999, 8 palm vipers (Bothriechis marchi) were diagnosed with a disease similar to inclusion body disease (IBD) of boids. Six palm vipers were captive bred, and 2 were wild caught. All of the vipers were adults at the time of death. Three palm vipers were …
Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease
Publication Year: 2003 Source: Clin Exp Immunol PMID: 12605697 DOI: 10.1046/j.1365-2249.2003.02079.x
Adhesion molecules regulate the influx of leukocytes in normal and inflamed gut. Some of these molecules such as MadCAM-1 are specific for the gastrointestinal endothelium, but in inflammatory bowel diseases most of the adhesion factors are up-regulated. Adhesion molecules also are involved in local lymphocyte stimulation and antigen presentation within …
Managing the refractory case of feline IBD
Publication Year: 2003 Source: J Feline Med Surg PMID: 12613493 DOI: 10.1053/jfms.2002.0196
Survival and Cause-Specific Mortality in Inflammatory Bowel Disease: A Population-Based Cohort Study. Persson PG, Bernell O, Leijonmarck CE, Farahmand BY, Hellers G, Ahlbom A. Gastroenterology 1996;110:1339-45.
Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease
Publication Year: 2003 Source: Oral Dis PMID: 12617256 DOI: 10.1034/j.1601-0825.2003.00879.x
BACKGROUND: alpha(1)-Acid glycoprotein (alpha(1)-AGP) is an acute phase protein in most mammalian species whose concentration rises 2-5-fold during an acute phase reaction. Its serum concentration has often been used as a marker of disease, including inflammatory bowel disease (IBD). High alpha(1)-AGP levels were found to have a prognostic value for …
Serological markers in inflammatory bowel diseases
Publication Year: 2003 Source: Best Pract Res Clin Gastroenterol PMID: 12617880 DOI: 10.1053/bega.2002.0347
Comment on Eur J Gastroenterol Hepatol. 2002 Oct;14(10):1061-6. Prophylactic colectomy is an established method of bowel cancer prevention in high-risk patients such as familial adenomatosis polyposis coli (FAP) and hereditary non-polyposis colorectal cancer (HNPCC) kindreds, as well as in patients with longstanding ulcerative colitis or Crohn's disease. The decision to …
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