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High normal serum levels of C3 and C1 inhibitor, two acute-phase proteins belonging to the complement system, occur more frequently in patients with Crohn's disease than ulcerative colitis

Publication Year: 2003 Source: Dig Dis Sci PMID: 12822883 DOI: 10.1023/a:1023793502456

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Modulation of cytokine release from colonic explants by bacterial antigens in inflammatory bowel disease

Publication Year: 2003 Source: Clin Exp Immunol PMID: 12823284 DOI: 10.1046/j.1365-2249.2003.02191.x

BACKGROUND: Platelet-derived endothelial cell growth factor (PD-ECGF) is reported to be highly expressed in tumors and inflammatory tissues, but its expression and role in inflammatory bowel disease (IBD) are still unclear. In this study we examined the location and tissue density of cells immunoreactive for PD-ECGF in the colonic mucosa …

Regulation of epithelial syndecan-1 expression by inflammatory cytokines

Publication Year: 2003 Source: Cytokine PMID: 12824007 DOI: 10.1016/s1043-4666(03)00091-7

Not found

Serum YKL-40, a potential new marker of disease activity in patients with inflammatory bowel disease

Publication Year: 2003 Source: Scand J Gastroenterol PMID: 12825867 DOI: 10.1080/00365520310000537

Not found

Colorectal cancer in patients with inflammatory bowel disease after liver transplantation for primary sclerosing cholangitis

Publication Year: 2003 Source: Transplantation PMID: 12829898 DOI: 10.1097/01.TP.0000058744.34965.38

Not found

Primary sclerosing cholangitis in children: a long-term follow-up study

Publication Year: 2003 Source: Hepatology PMID: 12830004 DOI: 10.1053/jhep.2003.50289

Commensal bacteria have emerged as an important disease factor in human Crohn's disease (CD) and murine inflammatory bowel disease (IBD) models. We recently isolated I2, a novel gene segment of microbial origin that is associated with human CD and that encodes a T-cell superantigen. To identify the I2 microorganism, BLAST …

Severe inflammatory bowel disease: medical management

Publication Year: 2003 Source: Dig Dis PMID: 12838000 DOI: 10.1159/000071339

Technetium-99m HMPAO labelled white cell scanning is now an accepted method for assessing the activity of inflammatory bowel disease. However, false positive results have been demonstrated. This study was conducted to assess the significance of low grade uptake on 99Tcm-HMPAO labelled white cell scans in the right iliac fossa (RIF) …

Is nutrition an aetiological factor for inflammatory bowel disease?

Publication Year: 2003 Source: Eur J Gastroenterol Hepatol PMID: 12840670 DOI: 10.1097/00042737-200306000-00005

Ulcerative colitis and colonic Crohn's disease (together known as inflammatory bowel disease or IBD) are both associated with increased risk for colorectal cancer. Although it is customary to emphasize differences in the biology of IBD-associated and sporadic colon cancer, we believe these are far outweighed by the similarities. These similarities …

Inflammatory bowel disease and liver transplantation for primary sclerosing cholangitis

Publication Year: 2003 Source: Eur J Gastroenterol Hepatol PMID: 12840678 DOI: 10.1097/00042737-200306000-00013

OBJECTIVE: Inflammatory bowel disease (IBD) is associated with an increased risk of colorectal cancer (CRC), but more knowledge is needed about the possible relationship between clinical parameters and the time to development of cancer in IBD. The aim of the study was to determine the variability of the colitis-CRC interval …

Immunohistochemical expression of FHIT gene product in inflammatory bowel disease: significance and correlation with clinicopathological data

Publication Year: 2003 Source: Eur J Gastroenterol Hepatol PMID: 12840679 DOI: 10.1097/00042737-200306000-00014

To define mediator profiles in inflamed and noninflamed areas in inflammatory bowel disease (IBD) we analyzed the expression of 35 messenger-RNAs (mRNAs) encoding cytokines, chemokines, and some related molecules in transmural gut tissues (n=138) from patients with ulcerative colitis (UC), Crohn's disease (CD), and inflammatory and normal controls by real-time …

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