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CT and 99mTc-WBC vs colonoscopy in the evaluation of inflammation and complications of inflammatory bowel diseases
Publication Year: 2002 Source: J Gastroenterol PMID: 11824796 DOI: 10.1007/s535-002-8128-5
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Effect of liver transplantation on inflammatory bowel disease in patients with primary sclerosing cholangitis
Publication Year: 2002 Source: Hepatology PMID: 11826412 DOI: 10.1053/jhep.2002.30695
The importance of health-related quality of life (HRQOL) assessment in patients with chronic disorders such as inflammatory bowel disease (IBD) is now acknowledged by researchers. Of the many factors that may influence HRQOL, patient knowledge of the condition and disease-related information provision have hitherto not been studied. In all, 250 …
Biological and novel therapies for inflammatory bowel disease in children
Publication Year: 2002 Source: Pediatr Clin North Am PMID: 11826800 DOI: 10.1016/s0031-3955(03)00106-8
Leukocytapheresis (LCAP) is widely used for the treatment of immunological diseases. We studied a new treatment of LCAP using a nonwoven polyester fiber filter. In a basic study, 30-70% of leukocytes were removed. Also, 30-68% of the leukocyte subsets were removed. Sixteen inflammatory bowel disease (IBD) patients, mainly with ulcerative …
Value of rectosigmoidoscopy with biopsies for diagnosis of inflammatory bowel disease in children
Publication Year: 2002 Source: Inflamm Bowel Dis PMID: 11837934 DOI: 10.1097/00054725-200201000-00003
In IBD, the target antigens of anti-neutrophil cytoplasmic autoantibodies (ANCA) have not been fully identified, which limits the analysis of the diagnostic significance as well as of the possible pathophysiological role of these antibodies. In this study, we identify the target antigens of ANCA in large groups of patients with …
Laparoscopic surgery for inflammatory bowel disease: results of the past decade
Publication Year: 2002 Source: Inflamm Bowel Dis PMID: 11837938 DOI: 10.1097/00054725-200201000-00007
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Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice
Publication Year: 2002 Source: Am J Pathol PMID: 11839595 DOI: 10.1016/S0002-9440(10)64894-8
Accurate knowledge of haplotypes, the combination of alleles co-residing on a single copy of a chromosome, enables powerful gene mapping and sequence imputation methods. Since humans are diploid, haplotypes must be derived from genotypes by a phasing process. In this study, we present a new computational model for haplotype phasing …
Hyperhomocysteinaemia, coagulation pathway activation and thrombophilia in patients with inflammatory bowel disease
Publication Year: 2002 Source: Scand J Gastroenterol PMID: 11843038 DOI: 10.1080/003655202753387374
BACKGROUND: The American Gastroenterology Association (AGA) published guidelines to assist clinicians in the evaluation and management of osteoporosis in inflammatory bowel disease (IBD) patients. Two studies suggest that when clinicians utilized the guidelines, the majority of their IBD patients were appropriately screened and treated for metabolic bone disease. The aim …
A polymorphism in the CD14 gene is associated with Crohn disease
Publication Year: 2002 Source: Scand J Gastroenterol PMID: 11843056 DOI: 10.1080/003655202753416867
OBJECTIVE: Inflammatory bowel diseases (IBD) are multifactorial disorders, characterized by failure to limit the inflammatory response to luminal antigens. Genetic factors play an important role in the pathogenesis, but little is known about the accountable genes. Increased secretion of pro-inflammatory cytokines appears crucial in the initiation of the inflammatory response. …
Vitamin D status, parathyroid hormone and bone mineral density in patients with inflammatory bowel disease
Publication Year: 2002 Source: Scand J Gastroenterol PMID: 11843057 DOI: 10.1080/003655202753416876
Comment on Eur J Gastroenterol Hepatol. 2001 Feb;13(2):101-6. The aetiology and pathogenesis of Crohn's disease (CD) remain to be elucidated. In addition to genetic influences and immune mediated cytokine gene activation, various specific and non-specific environmental factors are considered to be associated with the induction and/or exacerbation of inflammatory bowel …
Antineutrophil cytoplasmic antibodies, anti-Saccharomyces cerevisiae antibodies, and specific IgE to food allergens in children with inflammatory bowel diseases
Publication Year: 2002 Source: Clin Immunol PMID: 11846458 DOI: 10.1006/clim.2001.5145
Comment in J Vet Intern Med. 2001 Jul-Aug;15(4):327-8. The present study sought to determine the spectrum of diseases associated with subnormal concentrations of serum cobalamin in cats undergoing investigation of suspected gastrointestinal problems. The solid-phase boil radioassay (RA) for cobalamin employed in the present study was immunologically specific, precise, and …
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