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Lower gastrointestinal bleeding and ischemic colitis

Publication Year: 2002 Source: Can J Gastroenterol PMID: 12362211 DOI: 10.1155/2002/374682

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) is a polygenic disorder, as demonstrated by epidemiological evidence, genetic linkage, and the identification of the first susceptibility gene, NOD2. Genetic linkage analysis has identified and replicated several genomic regions as locations for susceptibility genes, including chromosome 6p (termed IBD3). The HLA-DP genes …

Fundamental mechanisms of growth failure in inflammatory bowel disease

Publication Year: 2002 Source: Horm Res PMID: 12373006 DOI: 10.1159/000064756

A non-invasive diagnostic modality for differential diagnosis and detection of complications in inflammatory bowel disease (IBD) is desirable as alternative to invasive and troublesome endoscopy and conventional radiological methods. METHODS: 51 patients suspicious of inflammatory bowel disease (bloody diarrhoea, symptoms of stenosis, abdominal pain) were investigated consecutively according to a …

Granulocyte colony-stimulating factor in glycogen storage disease type 1b. Results of the European Study on Glycogen Storage Disease Type 1

Publication Year: 2002 Source: Eur J Pediatr PMID: 12373578 DOI: 10.1007/s00431-002-1010-0

Hepatocyte growth factor/scatter factor (HGF/SF) can stimulate growth of gastrointestinal epithelial cells in vitro; however, the physiological role of HGF/SF in the digestive tract is poorly understood. To elucidate this in vivo function, mice were analyzed in which an HGF/SF transgene was overexpressed throughout the digestive tract. Nearly a third …

Association of glycogen storage disease 1b and Crohn disease: results of a North American survey

Publication Year: 2002 Source: Eur J Pediatr PMID: 12373579 DOI: 10.1007/s00431-002-1011-z

Not found

Mucosal and invading bacteria in patients with inflammatory bowel disease compared with controls

Publication Year: 2002 Source: Scand J Gastroenterol PMID: 12374228 DOI: 10.1080/003655202320378220

OBJECTIVE: To characterize retroviruses isolated from boid snakes with inclusion body disease (IBD). ANIMALS: 2 boa constrictors with IBD and 1 boa exposed to an affected snake. PROCEDURE: Snakes were euthanatized, and tissue specimens and blood samples were submitted for virus isolation. Tissue specimens were cultured with or without commercially …

The value of tissue imprint hybridization for rapid detection of infectious bursal disease virus from field outbreaks

Publication Year: 2002 Source: Trop Anim Health Prod PMID: 12379057 DOI: 10.1023/a:1020040125341

A simple method of estimating IBD sharing (pi) of sibling pairs from multipoint genotype data based on linear regression is presented. The new method is an extension of that developed by Fulker, Cherny, and Cardon (1995) and involves a measure of sib-pair specific information, W, defined as the difference between …

Intestinal nematode infection ameliorates experimental colitis in mice

Publication Year: 2002 Source: Infect Immun PMID: 12379667 DOI: 10.1128/IAI.70.11.5931-5937.2002

Not found

Lamina propria and circulating interleukin-6 in newly diagnosed pediatric inflammatory bowel disease patients

Publication Year: 2002 Source: Am J Gastroenterol PMID: 12385446 DOI: 10.1111/j.1572-0241.2002.06030.x

The objectives of this paper are to review the rational, the present results and future of laparoscopic-assisted bowel surgery in patients with inflammatory bowel disease (IBD). Only a few centres in the world report on laparoscopic bowel resection in IBD that include stoma surgery, ileocolic resection, left, right and (sub)total …

Antitumour necrosis factor therapy in Crohn's disease

Publication Year: 2002 Source: Expert Opin Biol Ther PMID: 12387670 DOI: 10.1517/14712598.2.7.715

The use of a peroxidase labelled PCR generated probe followed by enhanced chemiluminescence hybridization assay detected infectious bursal disease virus directly from bursal imprints on a nylon membrane. Tissue imprint hybridization proved to be a simple, rapid and safe means of detecting IBD virus for screening large numbers of field …

Asthma and multiple sclerosis: an inverse association in a case-control general practice population

Publication Year: 2002 Source: QJM PMID: 12391388 DOI: 10.1093/qjmed/95.11.753

We propose a new splitting rule for recursively partitioning sibpair data into relatively more homogeneous subgroups. This strategy is designed to identify subgroups of sibpairs such that within-subgroup analyses result in increased power to detect linkage using Haseman-Elston regression. We assume that the subgroups can be defined by patterns of …

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