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Malignancies in inflammatory bowel disease: fact or fiction?
Publication Year: 2002 Source: Scand J Gastroenterol Suppl PMID: 12408504 DOI: 10.1080/003655202320621454
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Laparoscopic surgery for inflammatory bowel disease: current concepts
Publication Year: 2002 Source: Scand J Gastroenterol Suppl PMID: 12408505 DOI: 10.1080/003655202320621463
AIM: To report on the preliminary development of a short scale, the Edinburgh inflammatory bowel disease questionnaire (EIBDQ) to measure disease specific aspects of inflammatory bowel disease (IBD) in terms of both physical impact and health related quality of life (HRQoL) consequences. METHODS: A survey of individuals with Crohn's disease …
Prevalence and significance of inflammatory bowel disease-like morphologic features in collagenous and lymphocytic colitis
Publication Year: 2002 Source: Am J Surg Pathol PMID: 12409717 DOI: 10.1097/00000478-200211000-00003
Inflammatory bowel diseases (IBD)--Crohn's disease and ulcerative colitis--are relapsing chronic inflammatory disorders which involve genetic, immunological, and environmental factors. The regulation of TNF-alpha, a key mediator in the inflammatory process in IBD, is interconnected with mitogen-activated protein kinase pathways. The aim of this study was to characterize the activity and …
Pharmacogenomics of response to anti-tumor necrosis factor therapy in patients with Crohn's disease
Publication Year: 2002 Source: Am J Pharmacogenomics PMID: 12421092 DOI: 10.2165/00129785-200202040-00001
Erratum in Inflamm Bowel Dis. 2009 Sep;15(9):1438-47.
Interleukin-1 receptor antagonist VNTR-polymorphism in inflammatory bowel disease
Publication Year: 2002 Source: Genes Immun PMID: 12424621 DOI: 10.1038/sj.gene.6363888
Patients with inflammatory bowel disease (IBD) often question their doctors about diet. The objectives of this article are to provide clinicians with existing dietary advice by presenting the dietary information proposed by medical societies in the form of clinical practice guidelines as it relates to IBD; listing dietary guidelines from …
Examination, prevention and treatment of osteoporosis in patients with inflammatory bowel disease: recommendations and reality
Publication Year: 2002 Source: Acta Med Austriaca PMID: 12424936 DOI: 10.1046/j.1563-2571.2002.02018.x
BACKGROUND/AIMS: The normal intestinal epithelium is increasingly being recognised as an important component of the mucosal innate protection against microorganisms. Human neutrophil defensins 1-3 (HNP 1-3) and lysozyme are components of the systemic innate immunity. The aim of this study was to investigate the expression of HNP 1-3 and lysozyme …
Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity
Publication Year: 2002 Source: J Investig Med PMID: 12425429 DOI: 10.1136/jim-50-06-02
OBJECTIVE: Previous reports suggest an association between inflammatory bowel disease (IBD) and immune thrombocytopenic purpura (ITP) in adults. To date, only five children with both diseases have been described. The aim of the study was to describe the characteristics of children with IBD and ITP. METHODS: Cases were obtained from …
Risk factors associated with the introduction of acute clinical infectious bursal disease among Danish broiler chickens in 1998
Publication Year: 2002 Source: Avian Pathol PMID: 12425789 DOI: 10.1080/03079450120106000a
OBJECTIVE: Household members of patients with inflammatory bowel disease (IBD) are impacted in their daily lives by close interaction with chronic illness. However, the effect of IBD on the quality of life of household members has not been evaluated because appropriate instruments to measure it are lacking. The aim of …
Precision of methods for calculating identity-by-descent matrices using multiple markers
Publication Year: 2002 Source: Genet Sel Evol PMID: 12427386 DOI: 10.1186/1297-9686-34-5-557
The peroxisome proliferator-activated receptor gamma (PPAR gamma) has recently been implicated in the pathogenesis of inflammatory bowel disease (IBD) and colon cancer. The observation that PPAR gamma agonists, through immune modulation, protect against inflammatory processes in the intestine justified their expedient evaluation in the clinical management of IBD. PPAR gamma …
Impact of parental relationships in maximum lod score affected sib-pair method
Publication Year: 2002 Source: Genet Epidemiol PMID: 12432507 DOI: 10.1002/gepi.10190
As a result of extensive clinical and basic research, the pivotal role of tumour necrosis factor (TNF) in the pathogenesis of chronic inflammatory diseases such as inflammatory bowel disease (IBD) has now generally been acknowledged. This has led to promising clinically effective anti-TNF-strategies. Of note, there is more and more …
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