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Pathology of inflammatory bowel diseases (IBD): variability with time and treatment

Publication Year: 2001 Source: Colorectal Dis PMID: 12791013 DOI: 10.1046/j.1463-1318.2001.00187.x

Laparoscopic colectomy is one of the most difficult laparoscopic procedures. Surgeons attempting to perform laparoscopic surgery for inflammatory bowel disease (IBD) must have significant experience with IBD and advanced laparoscopic skills. Surgical management for IBD may be treated with a range of laparoscopic procedures that vary in complexity. After 10 …

Lactococcus lactis, a tool for the delivery of therapeutic proteins treatment of IBD

Publication Year: 2001 Source: ScientificWorldJournal PMID: 12805677 DOI: 10.1100/tsw.2001.37

Because causes of inflammatory bowel disease (IBD) remain obscure and a curative therapy is still lacking, the influence of stem-cell transplantation (SCT) on IBD is of major interest. We retrospectively analyzed the course of seven patients with Crohn's disease and four patients with idiopathic ulcerative colitis who underwent allogeneic SCT …

Altered glycosylation in inflammatory bowel disease: a possible role in cancer development

Publication Year: 2001 Source: Glycoconj J PMID: 12820718 DOI: 10.1023/a:1022240107040

BACKGROUND AND AIMS: Angiogenesis is an important component of tissue regeneration. As Inflammatory bowel disease (IBD) involves inflammation, ulceration, and regeneration of the intestinal mucosa, angiogenesis may be an integral part of IBD pathology. This study investigated the role of vascular endothelial growth factor in IBD. PATIENTS AND METHODS: The …

Progress toward discovery of susceptibility genes for bipolar manic-depressive illness and schizophrenia

Publication Year: 2001 Source: CNS Spectr PMID: 15311192 DOI: 10.1017/s1092852900001073

This review summarizes the complex role of heat-shock proteins (Hsp) in immune reactions, especially the cellular effects of heat-shock proteins during the recognition processes by innate immunity. The role of heat-shock proteins in the pathogenesis of two multifactorial diseases, i.e. inflammatory bowel disease (IBD) and atherosclerosis is highlighted. A new …

Coordinate upregulation of interleukin-8 and growth-related gene product-alpha is present in the colonic mucosa of inflammatory bowel

Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11495082 DOI: 10.1080/003655201750313397

BACKGROUND AND AIMS: Patient-reported outcome measures (PROMs) make it possible to assess health-status problems from the perspective of persons suffering from a disease. The objective of the paper is to examine and compare the contents of PROMs related to IBD based on the World Health Organization's International Classification of Functioning, …

Small-area variations and sociodemographic correlates for the incidence of Crohn's disease and ulcerative colitis

Publication Year: 2001 Source: Am J Epidemiol PMID: 11495856 DOI: 10.1093/aje/154.4.328

OBJECTIVE: Crohn's disease (CD) and ulcerative colitis (UC) may both affect the colon. However, in approximately 10-20% of these cases, it is impossible to distinguish between these two entities either clinically or histologically, and a diagnosis of indeterminate colitis (IC) is made. Correct diagnosis is important because surgical treatment and …

[A consecutive study of patients with irritable bowel disease in two tertiary referral centers]

Publication Year: 2001 Source: Psychother Psychosom Med Psychol PMID: 11496445 DOI: 10.1055/s-2001-15625

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PBSC autotransplant for inflammatory bowel disease (IBD): a case of ulcerative colitis

Publication Year: 2001 Source: Bone Marrow Transplant PMID: 11498755 DOI: 10.1038/sj.bmt.1703103

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The mucosal immune system: from specialized immune defense to inflammation and allergy

Publication Year: 2001 Source: Acta Odontol Scand PMID: 11501883 DOI: 10.1080/000163501750266738

Transforming growth factor-alpha (TGF-alpha) is overexpressed in colonic carcinomas and promotes mucosal wound healing. It may be implicated in chronic inflammatory bowel disease (IBD). We analyzed the expression of TGF-alpha and its receptor, epidermal growth factor receptor (EGF-r), in the colonic mucosa of patients with Crohn's disease (CD) or ulcerative …

Multipoint analysis using affected sib pairs: incorporating linkage evidence from unlinked regions

Publication Year: 2001 Source: Genet Epidemiol PMID: 11507720 DOI: 10.1002/gepi.1021

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