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Treatment of inflammatory bowel disease in the adolescent
Publication Year: 2001 Source: J Infus Nurs PMID: 11507789 DOI: 10.1097/00129804-200107000-00010
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Prediction of response to iron sucrose in inflammatory bowel disease-associated anemia
Publication Year: 2001 Source: Am J Gastroenterol PMID: 11513178 DOI: 10.1111/j.1572-0241.2001.04094.x
OBJECTIVE: To identify the frequency of use and appropriate monitoring guidelines for the adverse effects of azathioprine and 6-mercaptopurine (6-MP) in the therapy of patients with inflammatory bowel disease (IBD). METHODS: Surveys were sent to all physician members of the Canadian Association of Gastroenterology. Physicians were asked to describe their …
A prospective cohort study of practice guidelines in inflammatory bowel disease
Publication Year: 2001 Source: Am J Gastroenterol PMID: 11513181 DOI: 10.1111/j.1572-0241.2001.04042.x
Inflammatory bowel disease (IBD) is a chronic relapsing disorder affecting the gastro-intestinal tract and is subdivided into two main subtypes: Crohn's disease (CD) and ulcerative colitis (UC). Although the aetiology of IBD is unknown, a strong genetic susceptibility is suggested and different candidate regions have been identified for both CD …
An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11515842 DOI: 10.1097/00054725-200108000-00001
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Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11515844 DOI: 10.1097/00054725-200108000-00003
The mucosal immune system is a first line of defense against foreign antigens, including microbial and dietary antigens. Under normal circumstances, the mucosal immune system employs tightly regulated dynamic mucosal intra- and internets consisting of inductive and effector sites for the induction of an appropriate immunological homeostasis between the host …
Epithelial expression of caveolin-2, but not caveolin-1, is enhanced in the inflamed mucosa of patients with ulcerative colitis
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11515846 DOI: 10.1097/00054725-200108000-00005
Identification of genes involved in complex traits by traditional (lod score) linkage analysis is difficult due to many complicating factors. An unfortunate drawback of non-parametric procedures in general, though, is their low power to detect genetic effects. Recently, Dudoit and Speed [2000] proposed using a (likelihood-based) score test for detecting …
The expression of IL-12 p40 and its homologue, Epstein-Barr virus-induced gene 3, in inflammatory bowel disease
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11515847 DOI: 10.1097/00054725-200108000-00006
Comment in Eur J Gastroenterol Hepatol. 2004 Oct;16(10):1071-2; author reply 1072. BACKGROUND: As treatment of steroid-dependent patients with inflammatory bowel disease (IBD) is controversial, we analysed the efficacy and tolerance of 6-mercaptopurine (6-MP) and methotrexate (MTX) added to prednisone in increasing and maintaining the disease remission rate. METHODS: Seventy-two steroid-dependent …
Altered response of intestinal mucosal fibroblasts to profibrogenic cytokines in inflammatory bowel disease
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11515849 DOI: 10.1097/00054725-200108000-00008
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Application of Eudragit P-4135F for the delivery of ellagic acid to the rat lower small intestine
Publication Year: 2001 Source: J Pharm Pharmacol PMID: 11518017 DOI: 10.1211/0022357011776469
OBJECTIVES: The ileal pouch anal anastomosis is a safe and effective procedure but is also associated with pouchitis, small bowel obstruction, and incontinence. We prospectively evaluated the health-related quality of life using generic and disease-specific measures in a cohort of patients with ulcerative colitis undergoing ileal pouch anal anastomosis. METHODS: …
Helicobacter-induced inflammatory bowel disease in IL-10- and T cell-deficient mice
Publication Year: 2001 Source: Am J Physiol Gastrointest Liver Physiol PMID: 11518689 DOI: 10.1152/ajpgi.2001.281.3.G764
It has been well established that children with a chronic disease, including those with inflammatory bowel disease (IBD) and juvenile idiopathic arthritis (JIA), report lower health-related quality of life (HRQOL) as compared to their healthy peers. Over the past 20 years there has been a significant emphasis on the development …
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