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Understanding inflammatory bowel disease--the clinician's perspective
Publication Year: 2001 Source: Eur J Surg Suppl PMID: 11718529 DOI: 10.1080/110241501317076281
The gastrointestinal immune system is a major component of the mucosal barrier to foreign antigens including microbial and dietary antigens. Under normal circumstances, the mucosal immune system employs tightly regulated dynamic mucosal intra- and internets for the maintenance of an appropriate immunological balance between the host and gut environments. For …
Chemokine receptor CXCR3 expression in inflammatory bowel disease
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11720316 DOI: 10.1097/00054725-200111000-00001
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Secondary amyloidosis in inflammatory bowel disease: a study of 18 patients admitted to Rikshospitalet University Hospital, Oslo, from 1962 to 1998
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11720318 DOI: 10.1097/00054725-200111000-00003
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Anti-TNF therapies have eliminated the need for steroids in pediatric Crohn's disease: con. Why use a drug with an unknown long-term safety profile if more established therapies will be effective?
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11720327 DOI: 10.1097/00054725-200111000-00012
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MMR and IBD: the only thing we have to fear is...fear itself
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11720330 DOI: 10.1097/00054725-200111000-00016
BACKGROUND: Osteopenia and osteoporosis are commonly seen in inflammatory bowel disease (IBD). Vitamin D deficiency potentially contributes to diminished bone acquisition in childhood. OBJECTIVES: The objectives of this study were to assess vitamin D in a group of Australian children with IBD and to ascertain associations between vitamin D status …
Cyclosporine, or cyclosporine not, for severe ulcerative colitis
Publication Year: 2001 Source: Inflamm Bowel Dis PMID: 11720331 DOI: 10.1097/00054725-200111000-00017
Sustained damage to the mucosal lining in patients with inflammatory bowel disease (IBD) facilitates translocation of intestinal microbes to submucosal immune cells leading to chronic inflammation. Previously, we demonstrated the role of Jak3 in IL-2-induced intestinal epithelial cell (IEC) migration, one of the early events during intestinal wound repair. In …
Costs of care for irritable bowel syndrome patients in a health maintenance organization
Publication Year: 2001 Source: Am J Gastroenterol PMID: 11721759 DOI: 10.1111/j.1572-0241.2001.05258.x
Increased expression of CD40 and CD40 ligand (CD40L or CD154) has been found in inflamed mucosa of human inflammatory bowel disease (IBD), and interactions between these molecules seem to be involved in local cytokine production by macrophages. However, the precise role of CD40 signaling in the pathogenesis of IBD is …
Current topics on cytapheresis technologies
Publication Year: 2001 Source: Ther Apher PMID: 11724514 DOI: 10.1046/j.1526-0968.2001.00358.x
Longitudinal surveys of commercial Pekin ducks from four farms with a history of poor flock performance and high mortality rate showed that there was lymphoid depletion of the bursa of Fabricius in most ducks selected from 7 days of age onward. Such lesions were not present in Pekin ducks from …
Immunotherapeutic approaches to inflammatory bowel diseases
Publication Year: 2001 Source: Expert Opin Biol Ther PMID: 11727518 DOI: 10.1517/14712598.1.3.455
OBJECTIVES: To describe, implement, and test an efficient algorithm to obtain multipoint identity-by-descent (IBD) probabilities at arbitrary positions among marker loci for general pedigrees. Unlike existing programs, our algorithm can analyze data sets with large numbers of people and markers. The algorithm has been implemented in the SimWalk2 computer package. …
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice
Publication Year: 2001 Source: Gastroenterology PMID: 11729116 DOI: 10.1053/gast.2001.29579
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