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Efficacy of the inflammatory cell infiltration inhibitor IS-741 on colitis induced by dextran sulfate sodium in the rat
Publication Year: 2001 Source: Jpn J Pharmacol PMID: 11700014 DOI: 10.1254/jjp.87.151
Corticosteroids and 5-amino salicylic acid (5-ASA) are established therapies in the induction of remission and in maintenance of remission in patients with ulcerative colitis. 5-ASA exists in different delivery systems, however, clinical studies directly comparing these preparations exist only in very limited numbers. When analyzing placebo-controlled or comparative studies it …
Diagnostic misclassification reduces the ability to detect linkage in inflammatory bowel disease genetic studies
Publication Year: 2001 Source: Gut PMID: 11709510 DOI: 10.1136/gut.49.6.773
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The prevalence and incidence of peripheral arthritis in patients with inflammatory bowel disease, a prospective population-based study (the IBSEN study)
Publication Year: 2001 Source: Rheumatology (Oxford) PMID: 11709609 DOI: 10.1093/rheumatology/40.11.1256
Thromboembolic disease is a significant cause of morbidity and mortality in patients with inflammatory bowel disease (IBD). It is recognized that a hypercoagulable state exists in IBD which involves all components of the clotting system. It has been suggested that this hypercoagulable state is closely linked to the disease pathogenesis. …
A simple and rapid method for calculating identity-by-descent matrices using multiple markers
Publication Year: 2001 Source: Genet Sel Evol PMID: 11712969 DOI: 10.1186/1297-9686-33-5-453
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A novel approach to search for identity by descent in small samples of patients and controls from the same mendelian breeding unit: a pilot study on myopia
Publication Year: 2001 Source: Hum Hered PMID: 11713414 DOI: 10.1159/000053375
BACKGROUND: The significance of early membrane exposure on the regenerative outcome in guided tissue regeneration (GTR) and guided bone regeneration (GBR) procedures is somewhat controversial. Several clinical trials have shown better response when the membranes remained submerged (S) compared to those that have become exposed (E) during healing. Other studies …
Tissue cytokine and chemokine expression in inflammatory bowel disease
Publication Year: 2001 Source: Inflamm Res PMID: 11713901 DOI: 10.1007/PL00000223
The RT-PCR technique was adopted to amplify variable region of VP2 gene of infectious bursal disease virus using three different sets of primers. These primers could generate products of 643, 474 and 552 bp sizes. The authenticity of the amplicons was confirmed by their size in agarose gel, restriction enzyme …
Genetic determinants of IL-6 expression levels do not influence bone loss in inflammatory bowel disease
Publication Year: 2001 Source: Dig Dis Sci PMID: 11713964 DOI: 10.1023/a:1012300609279
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High prevalence of Mycoplasma pneumoniae in intestinal mucosal biopsies from patients with inflammatory bowel disease and controls
Publication Year: 2001 Source: Dig Dis Sci PMID: 11713965 DOI: 10.1023/a:1012352626117
Comment in Gastroenterology. 1999 Mar;116(3):778-9. Gastroenterology. 1999 Jul;117(1):280. Gastroenterology. 1999 Jul;117(1):280-1. BACKGROUND & AIMS: Thromboembolic disease is a significant cause of morbidity and mortality in patients with inflammatory bowel disease (IBD). The aim of this study was to determine the incidence and possible association of the factor V Leiden mutation …
CD4 T cells monospecific to ovalbumin produced by Escherichia coli can induce colitis upon transfer to BALB/c and SCID mice
Publication Year: 2001 Source: Int Immunol PMID: 11717197 DOI: 10.1093/intimm/13.12.1561
ETHNOPHARMACOLOGICAL RELEVANCE: Pulvis Fellis Suis is used in folk medicines to treat intestinal diseases, acute pharyngitis, whooping cough and asthma in China. Although several reports indicate that Pulvis Fellis Suis display diverse biological activities, such as antibacterial, anti-inflammatory and anti-infusorian effects, its effects on ulcerative colitis have not been previously …
New therapeutic possibilities in inflammatory bowel disease
Publication Year: 2001 Source: Eur J Surg Suppl PMID: 11718522 DOI: 10.1080/110241501317076227
This paper summarizes the results of searching for evidence of loci contributing to simulated quantitative traits which are associated with a common genetic disease using two multipoint identity by descent (IBD) sharing methods: MIM and MAPMAKER/SIBS. In brief, by varying the lod-score threshold from 1 to 3, we found that …
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