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Power of multipoint identity-by-descent methods to detect linkage using variance component models
Publication Year: 2001 Source: Genet Epidemiol PMID: 11754465 DOI: 10.1002/gepi.1035
Ulcerative colitis and Crohn's disease are chronic inflammatory bowel diseases (IBDs) with a chronic relapsing course. The aetiology of these diseases remains unknown, but in the last decade an increase in experimental models of IBD has led to expansion of our understanding in various aspects of the aetiology and pathogenic …
Probiotics in IBD
Publication Year: 2001 Source: Gut PMID: 11758502 DOI: 10.1136/gut.49.6.873a
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Reduced plasma antioxidant concentrations and increased oxidative DNA damage in inflammatory bowel disease
Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11761019 DOI: 10.1080/003655201317097146
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Seroprevalence of Helicobacter pylori infection in inflammatory bowel disease: is Helicobacter pylori infection a protective factor?
Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11761020 DOI: 10.1080/003655201317097155
A linkage disequilibrium-based method for fine mapping quantitative trait loci (QTL) has been described that uses similarity between individuals' marker haplotypes to determine if QTL alleles are identical by descent (IBD) to model covariances among individuals' QTL alleles for a mixed linear model. Mapping accuracy with this method was found …
Activated platelets in ulcerative colitis enhance the production of reactive oxygen species by polymorphonuclear leukocytes
Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11761021 DOI: 10.1080/003655201317097164
The objectives of this study were to describe variations in the incidence of inflammatory bowel disease (IBD) within the Canadian province of Manitoba and to analyze sociodemographic factors associated with these variations. The authors used the Manitoba Health insurance databases to measure incidence rates of Crohn's disease and ulcerative colitis …
Musculoskeletal manifestations in a population-based cohort of inflammatory bowel disease patients
Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11761022 DOI: 10.1080/003655201317097173
The diagnosis of inflammatory bowel disease (IBD) needs a complex diagnostic work-up. Beside verifying the disease itself, it is fundamental to assess disease extent and activity and to detect associated complications, to find the most effective treatment and for follow up. Scintigraphy with radiolabelled leukocytes is able to provide a …
Therapeutic effect of phenantroline in two rat models of inflammatory bowel disease
Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11761023 DOI: 10.1080/003655201317097182
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Self-care agency and quality of life among adults diagnosed with inflammatory bowel disease
Publication Year: 2001 Source: Qual Life Res PMID: 11763250 DOI: 10.1023/a:1012271520972
Studies have suggested that Tc-99m white blood cell (WBC) imaging is superior to contrast radiology for assessing the extent and activity of inflammatory bowel disease (IBD). The Tc-99m WBC scan seems ideally suited to obtain, in only one examination, a precise temporal snapshot of the distribution and intensity of inflammation, …
Prostaglandin biology in inflammatory bowel disease
Publication Year: 2001 Source: Gastroenterol Clin North Am PMID: 11764538 DOI: 10.1016/s0889-8553(05)70223-5
The aim of the study was to demonstrate the effects of dopaminergic drugs on 2,4-dinitrofluorbenzene (DNFB) induced experimental inflammatory bowel disease (IBD) in previously sensitized BALB/c mice. The number and extent of ulcerations and erosions, the intensity of haemorrhages, oedema, and accumulation of neutrophils and eosinophils within colonic lamina propria …
The bacterial flora in inflammatory bowel disease: current insights in pathogenesis and the influence of antibiotics and probiotics
Publication Year: 2001 Source: Scand J Gastroenterol Suppl PMID: 11768558 DOI: 10.1080/003655201753265082
CT colonography (CTC), or virtual colonoscopy, is a non-invasive imaging method that uses CT data sets combined with specialized imaging software to examine the colon. CTC is not used routinely in patients with inflammatory bowel disease (IBD). However, investigating contemporarily the colon, other abdominal organs and the peritoneum with CTC …
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