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A clustering approach for localizing disease susceptibility loci
Publication Year: 2001 Source: Genet Epidemiol PMID: 11793732 DOI: 10.1002/gepi.2001.21.s1.s534
The appearance of the gallbladder in images of patients undergoing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) autologous white cell scans (AWCSs) was compared before and after the introduction of fasting in the white cell scan protocol in our department. Before February 1995, when fasting was not required as a condition of the …
Multipoint linkage analysis under heterogeneity: incorporation of parametric and nonparametric approaches
Publication Year: 2001 Source: Genet Epidemiol PMID: 11793735 DOI: 10.1002/gepi.2001.21.s1.s55
OBJECTIVES: We investigated the nature of illness behavior and the meaning of emotional deficiencies during childhood in patients with irritable bowel diseases (IBS). DATA: A consecutive study in two tertiary referral centers was conducted with 48 patients suffering from irritable bowel diseases (IBS) and 91 patients with inflammatory bowel disease …
Should we consider gene x environment interaction in the hunt for quantitative trait loci?
Publication Year: 2001 Source: Genet Epidemiol PMID: 11793788 DOI: 10.1002/gepi.2001.21.s1.s831
Erratum in Genet Med 1999 Sep-Oct;1(6):247. PURPOSE: The inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis (UC) are chronic intestinal disorder of unknown etiology. Genetic factors play an important role in the pathogenesis of these diseases, but with a complex pattern of inheritance. A number of genome-wide scans …
Historical origins of current IBD concepts
Publication Year: 2001 Source: World J Gastroenterol PMID: 11819757 DOI: 10.3748/wjg.v7.i2.175
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Non-invasive investigation of inflammatory bowel disease
Publication Year: 2001 Source: World J Gastroenterol PMID: 11819811 DOI: 10.3748/wjg.v7.i4.460
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Spatial distribution and histogenesis of colorectal Paneth cell metaplasia in idiopathic inflammatory bowel disease
Publication Year: 2001 Source: J Gastroenterol Hepatol PMID: 11851832 DOI: 10.1046/j.1440-1746.2001.02629.x
We had previously reported that the protective effect of taurine against indomethacin-induced gastric mucosal injury was due to its antioxidant effects, which inhibited lipid peroxidation and neutrophil activation. In this study, we examined the effect of taurine on reducing the inflammatory parameters of trinitrobenzene sulfonic acid (TNBS)-induced inflammatory bowel disease …
Observer variation of diagnoses based on simple biopsy criteria differentiating among Crohn's disease, ulcerative colitis, and other forms of colitis
Publication Year: 2001 Source: J Gastroenterol Hepatol PMID: 11851834 DOI: 10.1046/j.1440-1746.2001.02638.x
Splice variants of the glycoprotein CD44 are transiently expressed on lymphocytes during T cell activation. Increased expression of CD44v6 on peripheral blood lymphocytes (PBL) of patients with inflammatory bowel disease (IBD) was described recently. The aim of this study was therefore to characterize CD44v6 expression on CD4(+) lamina propria lymphocytes …
Sources of clinical referrals to an urban coloproctology unit in Italy
Publication Year: 2001 Source: Tech Coloproctol PMID: 11862560 DOI: 10.1007/s101510170001
OBJECTIVES: The combined measurement of perinuclear antineutrophil cytoplasmic autoantibodies (pANCA) and anti-Saccharomyces cerevisiae mannan antibodies (ASCA) has recently been suggested as a valuable diagnostic approach in inflammatory bowel disease (IBD). The aim of this study was to assess the value of detecting pANCA and ASCA in the differentiation between ulcerative …
Two-generation analysis of pollen flow across a landscape. III. Impact of adult population structure
Publication Year: 2001 Source: Genet Res PMID: 11865716 DOI: 10.1017/s0016672301005341
Most conventional forms of drug therapy suppress or modify the host immunoinflammatory response and neglect the other contributor to disease pathogenesis-the environmental microflora. Probiotics are live microbial food ingredients that alter the enteric microflora and have a beneficial effect on health. The rationale for using probiotics in IBD is mainly …
The relevance of gastrointestinal fistulae in clinical practice: a review
Publication Year: 2001 Source: Gut PMID: 11878790 DOI: 10.1136/gut.49.suppl_4.iv2
The rate and distance of instantaneous pollen flow in a population are parameters of considerable current interest for plant population geneticists and conservation biologists. We have recently developed an estimator (phi ft) of differentiation between the inferred pollen clouds that fertilize several females, sampled within a single population. We have …
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