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Possible causal association of idiopathic inflammatory bowel disease with thrombocytopenia in the dog

Publication Year: 2001 Source: J Am Anim Hosp Assoc PMID: 11204479 DOI: 10.5326/15473317-37-1-65

In order to model the effect of PTPN22 on rheumatoid arthritis (RA), we determined the combination of single-nucleotide-polymorphisms (SNPs) showing the strongest association with RA. Three SNPs (rs2476601-rs12730735-rs11102685) were selected for which we estimated the genotypic relative risks (GRRs) of the corresponding genotypes. On the basis of these GRRs we …

123Iodine-labelled anti-VCAM-1 antibody scintigraphy in the assessment of experimental colitis

Publication Year: 2001 Source: Eur J Gastroenterol Hepatol PMID: 11204806 DOI: 10.1097/00042737-200101000-00006

OBJECTIVE: Little is known about the clinical features and natural history of segmental colitis associated with diverticula. Our aim was to evaluate the incidence of segmental colitis associated with diverticula in patients undergoing colonoscopy, its clinical picture, and its outcome. METHODS: This was a multicenter, prospective study. Patients with inflammatory …

The polymorphism at position -174 of the IL-6 gene is not associated with inflammatory bowel disease

Publication Year: 2001 Source: Eur J Gastroenterol Hepatol PMID: 11204808 DOI: 10.1097/00042737-200101000-00008

Not found

Quantitative assessment of mast cells and expression of IgE protein and mRNA for IgE and interleukin 4 in the gastrointestinal tract of healthy dogs and dogs with inflammatory bowel disease

Publication Year: 2001 Source: Am J Vet Res PMID: 11212030 DOI: 10.2460/ajvr.2001.62.211

OBJECTIVES: Elevated platelet count is a well recognized marker of inflammatory bowel disease (IBD) activity. Thrombopoietin (TPO) is a critical cytokine in the physiological regulation of thrombopoiesis. The aim of this study was to investigate the serum levels of endogenous TPO in patients with IBD, the relationship between platelet counts …

Partial characterization of retroviruses from boid snakes with inclusion body disease

Publication Year: 2001 Source: Am J Vet Res PMID: 11212031 DOI: 10.2460/ajvr.2001.62.217

BACKGROUND: We wanted to estimate the incidence of irritable bowel syndrome (IBS) and functional dyspepsia (FD) in the general population, and the detection of colorectal tumor (CRT) and inflammatory bowel disease (IBD) after the diagnosis of IBS and FD. METHODS: Patients aged 20-79 years newly diagnosed with IBS (N = …

Colorectal cancer rates among first-degree relatives of patients with inflammatory bowel disease: a population-based cohort study

Publication Year: 2001 Source: Lancet PMID: 11214128 DOI: 10.1016/S0140-6736(00)03612-6

Not found

Immune cell populations within the duodenal mucosa of dogs with enteropathies

Publication Year: 2001 Source: J Vet Intern Med PMID: 11215906 DOI: 10.1892/0891-6640(2001)015<0014:icpwtd>2.3.co;2

BACKGROUND: Granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin (IL)-3 transmit a same signal needed for growth and activation in granulocytes and macrophages, because these receptors utilize a common beta chain. Little is known about growth factors for intestinal myeloid cells in lesions of inflammatory bowel disease (IBD). AIM: To find out …

Subnormal concentrations of serum cobalamin (vitamin B12) in cats with gastrointestinal disease

Publication Year: 2001 Source: J Vet Intern Med PMID: 11215907 DOI: 10.1892/0891-6640(2001)015<0026:scoscv>2.3.co;2

Not found

A critical review of epidemiological studies in inflammatory bowel disease

Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11218235 DOI: 10.1080/00365520150218002

BACKGROUND: Previous studies have shown an increased risk of inflammatory bowel disease (IBD) among relatives of patients with Crohn disease and ulcerative colitis. In the present study the probandwise concordance rates for ulcerative colitis and Crohn disease among mono- and dizygotic twins were estimated. Further we aimed to evaluate whether …

Validation of the inflammatory bowel disease questionnaire in Swedish patients with ulcerative colitis

Publication Year: 2001 Source: Scand J Gastroenterol PMID: 11218243 DOI: 10.1080/00365520150218093

OBJECTIVE: Acute lower gastrointestinal bleeding is a rare complication of Crohn's disease, which represents a diagnostic and therapeutic challenge. The aim of this study was to define epidemiological characteristics and therapeutic options of hemorrhagic forms of Crohn's disease. METHODS: Thirty-four cases of hemorrhagic forms of Crohn's disease were studied retrospectively. …

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